Pieces of Iowa’s Past, February 9, 2011

Pieces of Iowa’s Past, published by the Iowa State Capitol Tour Guides weekly during the legislative session, features historical facts about Iowa, the Capitol, and the early workings of state government. All historical publications are reproduced here with the actual spelling, punctuation, and grammar retained. February 9, 2011 THIS WEEK: Forty-fourth Iowa General Assembly

Pieces of Iowa’s Past, March 9, 2011

Pieces of Iowa’s Past, published by the Iowa State Capitol Tour Guides weekly during the legislative session, features historical facts about Iowa, the Capitol, and the early workings of state government. All historical publications are reproduced here with the actual spelling, punctuation, and grammar retained. March 9, 2011 THIS WEEK: The Future of the State Law Library

Pieces of Iowa’s Past, March 9, 2012

Pieces of Iowa’s Past, published by the Iowa State Capitol Tour Guides weekly during the legislative session, features historical facts about Iowa, the Capitol, and the early workings of state government. All historical publications are reproduced here with the actual spelling, punctuation, and grammar retained. March 7, 2012 THIS WEEK: Orgin of the Historical Department of Iowa BACKGROUND: Charles Aldrich Charles Aldrich served as Iowa Chief Clerk of the House of Representatives for the eighth (1860) and ninth (1862) general assemblies. He volunteered for the Union Army in 1862 and served with the Thirty-second Iowa Infantry for 18 months. Aldrich came to Webster City, Iowa, in 1857. He started the Hamilton Freeman newspaper. He was also involved in the publishing and editing of the Dubuque Times and Marshall County Times. In 1882, at age 53, he represented Hamilton County in the House of Representatives during the 19th General Assembly. He was appointed as the Curator of the State Historical Department at its creation in 1890.

Secure and Prepared Newsletter, November 2013, Vol. 9, no. 11

A bi-weekly newsletter for those involved in the fields of homeland security and/or emergency management

Voyage autour du monde sur la frégate "la Vénus" pendant les années 1836-1839. Tome 9 / , publié... par Abel Du Petit-Thouars,...

Comprend : Botanique ; Zoologie... Oiseaux... ; Zoologie... Reptiles... ; Physique... ; Zoologie... Poissons ; Zoologie... Oiseaux... ; Zoologie. Mammifères

ABD Promos, September 2013, Vol. 13, no. 9

The ABD Promos Newsletter is produced monthly and details Division announcements, holiday schedules, broker promotions and a newly listed codes clipout section, which is formatted to be stapled into the Iowa Liquor Quarterly Spirits Price Book.

ABD Promos, September 2012, Vol. 12, no. 9

The ABD Promos Newsletter is produced monthly and details Division announcements, holiday schedules, broker promotions and a newly listed codes clipout section, which is formatted to be stapled into the Iowa Liquor Quarterly Spirits Price Book.

Polymorphisms in toll-like receptor 4 and toll-like receptor 9 influence viral load in a seroincident cohort of HIV-1-infected individuals.

OBJECTIVES: Toll-like receptors (TLRs) are innate immune sensors that are integral to resisting chronic and opportunistic infections. Mounting evidence implicates TLR polymorphisms in susceptibilities to various infectious diseases, including HIV-1. We investigated the impact of TLR single nucleotide polymorphisms (SNPs) on clinical outcome in a seroincident cohort of HIV-1-infected volunteers. DESIGN: We analyzed TLR SNPs in 201 antiretroviral treatment-naive HIV-1-infected volunteers from a longitudinal seroincident cohort with regular follow-up intervals (median follow-up 4.2 years, interquartile range 4.4). Participants were stratified into two groups according to either disease progression, defined as peripheral blood CD4(+) T-cell decline over time, or peak and setpoint viral load. METHODS: Haplotype tagging SNPs from TLR2, TLR3, TLR4, and TLR9 were detected by mass array genotyping, and CD4(+) T-cell counts and viral load measurements were determined prior to antiretroviral therapy initiation. The association of TLR haplotypes with viral load and rapid progression was assessed by multivariate regression models using age and sex as covariates. RESULTS: Two TLR4 SNPs in strong linkage disequilibrium [1063 A/G (D299G) and 1363 C/T (T399I)] were more frequent among individuals with high peak viral load compared with low/moderate peak viral load (odds ratio 6.65, 95% confidence interval 2.19-20.46, P < 0.001; adjusted P = 0.002 for 1063 A/G). In addition, a TLR9 SNP previously associated with slow progression was found less frequently among individuals with high viral setpoint compared with low/moderate setpoint (odds ratio 0.29, 95% confidence interval 0.13-0.65, P = 0.003, adjusted P = 0.04). CONCLUSION: This study suggests a potentially new role for TLR4 polymorphisms in HIV-1 peak viral load and confirms a role for TLR9 polymorphisms in disease progression.

Secure and Prepared Newsletter, December 2013, Vol. 9, no. 12

A bi-weekly newsletter for those involved in the fields of homeland security and/or emergency management

Farm Families Alive and Well, Vol. 9, issue 2, 2003

News from Iowa’s Center for Agricultural Safety and Health (I-CASH)

Farm Families Alive and Well, Vol. 9, issue 3, 2003

News from Iowa’s Center for Agricultural Safety and Health (I-CASH)

Farm Families Alive and Well, Vol. 9, issue 4, 2003

News from Iowa’s Center for Agricultural Safety and Health (I-CASH)

Quick Reads, December 9, 2013

IDPH Quick Reads is an electronic newsletter produced by the Director’s Office at the Iowa Department of Public Health. IDPH Quick Reads are published every three to four weeks.