964 resultados para Big Five
Resumo:
Background:
Aim:
To examine the consistency of policies and documentation for withholding in-hospital resuscitation across health services.
Method:
An observational, qualitative review of hospital policy and documentation was conducted in June 2013 in three public and two private sector hospitals in metropolitan Melbourne. Not for resuscitation (NFR) forms were evaluated for physical characteristics, content, authorisation and decision-making. Hospital policies were coded for alerts, definition of futility and burden of treatment and management of discussions and dissent.
Results:
There was a lack of standardisation, with each site using its own unique NFR form and accompanying site-specific policies. Differences were found in who could authorise the decision, what was included on the form, the role of patients and families, and how discussions were managed and dissent resolved. Futility and burden of treatment were not defined independently. These inconsistencies across sites contribute to a lack of clarity regarding the decision to withhold resuscitation, and have implications for staff employed across multiple hospitals.
Conclusions:
NFR forms should be reviewed and standardised so as to be clear, uniform and consistent with the legislative framework. We propose a two-stage process of documentation. Stage 1 facilitates discussion of patient-specific goals of care and consideration of limitations of treatment. Stage 2 serves to communicate a NFR order. Decisions to withhold resuscitation are inherently complex but could be aided by separating the decision-making process from the communication of the decision, resulting in improved end-of-life care.
Resumo:
This article examines some of the tensions implicit in performing in peace contexts. Drawing on the community-based performance form playback theatre, the article interrogates the (citizen) artist/performer within the demands of improvised performance. The article investigates the demands on the actor in a practice context that features refugee and asylum-seeker audience members/participants: the way in which performative risk, the risk of intimacy, the risk of getting it wrong and the risk of shaming self and other are considered in light of the challenges associated with the specificity of the ethnicity, cultural context/s, values and protocols of these audiences.
Resumo:
Review of the Australian Burlesque Festival's Gala Event, The Big Tease.
Resumo:
The Reasons for Gambling Questionnaire (RGQ) consist of 15 items forming five factors: enhancement, social, money, recreation and coping. The RGQ was developed for use in the 2010 British Gambling Prevalence Survey (BGPS) and has now been employed in the second Social and Economic Impact Study (SEIS) of Gambling in Tasmania study conducted in 2011 in Australia. Given differences between Britain and Australia in terms of socio-demographic profiles, gambling cultures and attitudes, gambling access and availability, gambling regulation, and rates and patterns of gambling participation, the aims of this study were to analyse the RGQ data from the SEIS to: (1) determine the most commonly endorsed gambling motives in an Australian jurisdiction, (2) explore the factor structure of the RGQ in an Australian sample, and (3) explore how motives for gambling vary among different Australian population sub-groups. A representative sample of the Tasmanian population who had gambled in the previous 12 months (n = 2,796) were administered the RGQ via computer-assisted telephone interviewing. The five most commonly endorsed reasons for gambling were for fun (62 %), followed by the chance of winning big money (52 %), it being something to do with friends and family (48 %), to be sociable (40 %), and excitement (38 %). A principal component analysis revealed a five-factor structure that is slightly different from that derived in the BGPS: money, regulate internal state, positive feelings, social, and challenge reasons. Finally, gambling motives varied according to socio-demographic factors, number of gambling activities, problem gambling severity, and participation on different gambling activities. Although some of these findings are consistent with those from the BGPS, there are also some slight differences, suggesting that there may be regional-specific variations in gambling motives.
Resumo:
This study investigated the relationship between the Big 5, measured at factor and facet levels, and dimensions of both psychological and subjective well-being. Three hundred and thirty-seven participants completed the 30 Facet International Personality Item Pool Scale, Satisfaction with Life Scale, Positive and Negative Affectivity Schedule, and Ryff’s Scales of Psychological Well-Being. Cross-correlation decomposition presented a parsimonious picture of how well-being is related to personality factors. Incremental facet prediction was examined using double-adjusted r2 confidence intervals and semi-partial correlations. Incremental prediction by facets over factors ranged from almost nothing to a third more variance explained, suggesting a more modest incremental prediction than presented in the literature previously. Examination of semi-partial correlations controlling for factors revealed a small number of important facet-well-being correlations. All data and R analysis scripts are made available in an online repository.
Resumo:
Purpose:
Experimental Design:
Genes characteristic of the Hh MB subgroup were identified through published bioinformatic analyses. Thirty-two genes shown to be differentially expressed in fresh frozen and formalin-fixed paraffin-embedded tumor samples and reproducibly analyzed by RT-PCR were measured in matched samples. These data formed the basis for building a multi-gene logistic regression model derived through elastic net methods from which the five-gene Hh signature emerged after multiple iterations. Based on signature gene expression levels, the model computed a propensity score to determine Hh activation using a threshold set a priori. The association between Hh activation status and tumor response to the Hh pathway inhibitor sonidegib (LDE225) was analyzed.
Results:
Five differentially expressed genes in MB (GLI1, SPHK1, SHROOM2, PDLIM3, and OTX2) were found to associate with Hh pathway activation status. In an independent validation study, Hh activation status of 25 MB samples showed 100% concordance between the five-gene signature and Affymetrix profiling. Further, in MB samples from 50 patients treated with sonidegib, all six patients who responded were found to have Hh-activated tumors. Three patients with Hh-activated tumors had stable or progressive disease. No patients with Hh-nonactivated tumors responded.
Conclusions:
This five-gene Hh signature can robustly identify Hh-activated MB and may be used to preselect patients who might benefit from sonidegib treatment.
Resumo:
This paper introduces and investigates large iterative multitier ensemble (LIME) classifiers specifically tailored for big data. These classifiers are very large, but are quite easy to generate and use. They can be so large that it makes sense to use them only for big data. They are generated automatically as a result of several iterations in applying ensemble meta classifiers. They incorporate diverse ensemble meta classifiers into several tiers simultaneously and combine them into one automatically generated iterative system so that many ensemble meta classifiers function as integral parts of other ensemble meta classifiers at higher tiers. In this paper, we carry out a comprehensive investigation of the performance of LIME classifiers for a problem concerning security of big data. Our experiments compare LIME classifiers with various base classifiers and standard ordinary ensemble meta classifiers. The results obtained demonstrate that LIME classifiers can significantly increase the accuracy of classifications. LIME classifiers performed better than the base classifiers and standard ensemble meta classifiers.
Resumo:
Big data presents a remarkable opportunity for organisations to obtain critical intelligence to drive decisions and obtain insights as never before. However, big data generates high network traffic. Moreover, the continuous growth in the variety of network traffic due to big data variety has rendered the network to be one of the key big data challenges. In this article, we present a comprehensive analysis of big data variety and its adverse effects on the network performance. We present taxonomy of big data variety and discuss various dimensions of the big data variety features. We also discuss how the features influence the interconnection network requirements. Finally, we discuss some of the challenges each big data variety dimension presents and possible approach to address them.
Resumo:
Many mental health surveys and clinical studies do not include a multi-attribute utility instrument (MAUI) that produces quality-adjusted life-years (QALYs). There is also some question about the sensitivity of the existing utility instruments to mental health.
Resumo:
The three-dimensional interfacial grain boundary network in a fully austenitic high-manganese steel was studied as a function of all five macroscopic crystallographic parameters (i.e. lattice misorientation and grain boundary plane normal) using electron backscattering diffraction mapping in conjunction with focused ion beam serial sectioning. The relative grain boundary area and energy distributions were strongly influenced by both the grain boundary plane orientation and the lattice misorientation. Grain boundaries terminated by (1 1 1) plane orientations revealed relatively higher populations and lower energies compared with other boundaries. The most frequently observed grain boundaries were {1 1 1} symmetric twist boundaries with the Σ3 misorientation, which also had the lowest energy. On average, the relative areas of different grain boundary types were inversely correlated to their energies. A comparison between the current result and previously reported observations (e.g. high-purity Ni) revealed that polycrystals with the same atomic structure (e.g. face-centered cubic) have very similar grain boundary character and energy distributions. © 2014 Acta Materialia Inc. Published by Elsevier Ltd. All rights reserved.
