Schistosomiasis mansoni in Bananal (State of São Paulo, Brazil): IV. Study on the public awareness of its risks in the Palha District

A rather high prevalence of mansoni schistosomiasis has been observed in some localities of Bananal, State of São Paulo, during the past decade. The highest prevalence of schistosomiasis was found in the Palha District; it was thus considered adequate for an evaluation of public awareness of the risks involved in acquiring schistosomiasis, a likely outcome of certain behavior patterns. We interviewed 542 district-dwellers. The 5-to-39 age-group constituted 65.5% of the whole sample. Concerning the infection, 69.2% had hearsay information; 46.1% know the infection; 69.6% know how it is acquired; 31.5% know about the symptoms and 57.1% know what can be done to avoid infection; 17.7% declared to have acquired the infection at least once in their lifetime; 62.3% reported total or partial immersion in collections of water of Bananal, once or twice a week, 53.9% of these for bathing or fishing. Although most (91.7%) households have treated running water, are connected to the sewage network or have septic tanks, 9% of the people interviewed use to defecate on the field. It became clear that the educational messages aimed at this population had not been adequate, having failed to fulfil any expectations. The local people received only piecemeal and subjective information about their problem. The control of schistosomiasis requires an integrated practice, which includes the analysis of macro-determinant factors, such as basic sanitation, habitation, education and health care. In short, we require a multidisciplinary vision of the mechanisms of transmission of the infection, which depends upon adequate planning and well trained personnel, intent on their educational work, to attain satisfactory results.

Characterization of new Schistosoma mansoni microsatellite loci in sequences obtained from public DNA databases and microsatellite enriched genomic libraries

In the last decade microsatellites have become one of the most useful genetic markers used in a large number of organisms due to their abundance and high level of polymorphism. Microsatellites have been used for individual identification, paternity tests, forensic studies and population genetics. Data on microsatellite abundance comes preferentially from microsatellite enriched libraries and DNA sequence databases. We have conducted a search in GenBank of more than 16,000 Schistosoma mansoni ESTs and 42,000 BAC sequences. In addition, we obtained 300 sequences from CA and AT microsatellite enriched genomic libraries. The sequences were searched for simple repeats using the RepeatMasker software. Of 16,022 ESTs, we detected 481 (3%) sequences that contained 622 microsatellites (434 perfect, 164 imperfect and 24 compounds). Of the 481 ESTs, 194 were grouped in 63 clusters containing 2 to 15 ESTs per cluster. Polymorphisms were observed in 16 clusters. The 287 remaining ESTs were orphan sequences. Of the 42,017 BAC end sequences, 1,598 (3.8%) contained microsatellites (2,335 perfect, 287 imperfect and 79 compounds). The 1,598 BAC end sequences 80 were grouped into 17 clusters containing 3 to 17 BAC end sequences per cluster. Microsatellites were present in 67 out of 300 sequences from microsatellite enriched libraries (55 perfect, 38 imperfect and 15 compounds). From all of the observed loci 55 were selected for having the longest perfect repeats and flanking regions that allowed the design of primers for PCR amplification. Additionally we describe two new polymorphic microsatellite loci.

Opening statement by Mr Michael Scanlan, Secretary General of the Department of Health & Children at the meeting of the DÃil Committee of Public Accounts on 7th May 2009

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Report On Public Consultation: Efficiency And Effectiveness Of Disability Services In Ireland

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Public Service Agreement 2010 - 2014 (Croke Park Agreement) - Departmental Progress Report September 2011

1. Summary of Main Progress Achieved in the Six Month Period April 2011 to September 2011 ICT services and Accounts/Finance services are being provided by the Department to the new Department of Children and Youth Affairs on an ongoing basis.A Special Delivery Unit, as provided for in the Programme for Government, is currently being established.A survey of all staff workloads is currently underway to verify that all staff are appropriately deployed and utilised.   Click here to download PDF 46KB

Public Service Agreement 2010-2014 (Croke Park Agreement) - Departmental Progress Report - May 2011

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Public Service Agreement 2010 - 2014 (Croke Park Agreement): Departmental Action Plan

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Public Service Agreement - Health Sector Progress Report and Savings - May 2011

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Public Service Agreement - Health Sector Progress Report - October 2011

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Non-Commercial State Agencies - Public Service Agreement Progress Report - October 2011

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Public Service Agreement 2010-2014 - Health Sector Action Plan 2012

This revised Action Plan is designed to support the delivery of the HSEâ?Ts 2012 National Service Plan by facilitating the fast-tracking of measures required to deliver essential health and personal social services across the country within the context of further reductions in funding and staff numbers. The implementation of the National Service Plan, approved by the Minister for Health on 13 January 2012, represents a major challenge to the health services and comes at a time of major reform of the public health system.   Click here to download PDF 161kb

Public Service Agreement 2010-2014 (Croke Park Agreement) Integrated Departmental and Agencies Action Plan 2012

Public Service Agreement 2010-2014 (Croke Park Agreement) Integrated Departmental and Agencies Action Plan 2012 Integrated Departmental and Agencies Action Plan (Jan 2012) PDF 54kb Integrated Departmental and Agencies Action Plan (Oct 2012) PDF 194kb  

Public Service Agreement 2010-2014 (Croke Park Agreement) - Second Annual Progress, Savings and Productivity Reports for the Department and its Agencies

Public Service Agreement 2010-2014 (Croke Park Agreement) – Second Annual Progress, Savings and Productivity Reports for the Department and its Agencies Integrated Annual Progress Report for the Department and its Agencies PDF 327kb Annual Savings Report for the Department’s Agencies PDF 205kb Productivity Report for the Department and its Agencies PDF 205kb

Public Service Agreement - Revised Health Sector Action Plan - December 2012

The health service has been at the forefront in delivering significant change under the PSA. The substantial contribution already made by health service staff, especially during the period of concentrated retirements up to February 2012, is acknowledged and much appreciated by management. These changes are being achieved in what is a complex working environment with increasing demands, (500,000 increase in medical card holders between 2007 and 2012) and a growing and ageing population, within a public health service which is undergoing unprecedented organisational change and reform, accompanied by a reducing workforce. Public Service Agreement – Revised Health Sector Action Plan- December 2012 savings report Click here to download PDF 51kb

Public Service Agreement - Health Sector second annual progress and savings report

Department cover letters PDF 839kb Main health sector progress report PDF 11.1mb Traffic light document PDF 39kb Savings template PDF 268kb