Método para controle da qualidade de medicamentos sólidos por difração de raios X

Pós-graduação em Química - IQ

Estudo das alterações genéticas da Interleucina 28B em Astrocitomas

Pós-graduação em Pesquisa e Desenvolvimento (Biotecnologia Médica) - FMB

Caracterização morfológica e divergência genética em acessos de meloeiro

Pós-graduação em Agronomia (Genética e Melhoramento de Plantas) - FCAV

Seleção genômica e estudo de associação em um rebanho experimental da raça Nelore

Pós-graduação em Genética e Melhoramento Animal - FCAV

Molecular analysis of the PROP1 and HESX1 genes in patients with septo-optic dysplasia and/ or pituitary hormone deficiency

Objective: The present study aimed at evaluating the PROP1 and HESX1 genes in a group of patients with septo-optic dysplasia (SOD) and pituitary hormone deficiency (combined – CPHD; isolated GH deficiency – GHD). Eleven patients with a clinical and biochemical presentation consistent with CPHD, GHD or SOD were evaluated. Subjects and methods: In all patients, the HESX1 gene was analyzed by direct sequence analysis and in cases of CPHD the PROP1 gene was also sequenced. Results: A polymorphism (1772 A > G; N125S) was identified in a patient with SOD. We found three patients carrying the allelic variants 27 T > C; A9A and 59 A > G; N20S in exon 1 of the PROP1 gene. Mutations in the PROP1 and HESX1 genes were not identified in these patients with sporadic GHD, CPHD and SOD. Conclusion: Genetic alterations in one or several other genes, or non-genetic mechanisms, must be implicated in the pathogenic process.

Seleção assistida por marcadores para o melhoramento do desempenho de equinos em corridas

Although equines have participated in the forming and development of several civilizations around the world since their domestication 6,000 years ago in comparison to other species that have zootechnical interest, few researches have been done related to animal breeding area, especially in Brazil. Some reasons for that are difficulties associated with the species as well as operational aspects. However, developments in genetics in the last decades contributed to a better understanding of the traits related to reproduction, heath, behavior and performance of domestic animals, including equines. Recent technologies as next generation sequencing methods and the high density chips of SNPs for genotyping allowed some advances in the researches already done. These researches used basically the candidate gene strategy, and identified genomic regions related to diseases and syndromes and, more recently, the performance in sport competition and specific abilities. Using these genomic analysis tools, some regions related to race performance have been identified and based on this information; genetic tests to select superior animals for racing performance have started to be available in the market.

Germinação de sementes de maracujazeiros: água, luz, temperatura e reguladores vegetais

The production of seedlings of passion fruit is done mainly with the use of seeds by most producers. It can also be propagated by cuttings, layering and in vitro tissue culture. However, even when grafting is used, it is necessary to use seeds to produce the rootstock. Nevertheless, most Passifloracea species have germination problems, making it difficult to obtain seedlings. Although several studies have been developed in an attempt to increase seed germination of passion fruit there are still difficulties in understanding the germination process and also disagreement about seed dormancy. Thus, the present study aimed to review papers related to seed germination of passion fruit emphasizing aspects such as mechanical resistance to water ingress, the need for adequate light and temperature and the use of plant growth regulators in overcoming seed dormancy. It was noticed that, in general, the passion fruit seeds are photoblastic negative and exhibit physiological dormancy, being no need of seed scarification to stimulate its germination.

Análise de parentesco e variabilidade genética de pacu (Piaractus mesopotamicus) por meio de marcadores SNPs: subsídios para o melhoramento genético

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Investigação da funcionalidade de haplótipos no gene Interleucina 4

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Caracterização e comparação de Cotesia flavipes (Hymenoptera: braconidae) em situação de criação massal utilizando microssatélites e morfologia

Pós-graduação em Agronomia (Entomologia Agrícola) - FCAV

Polimorfismos de nucleotídeo único (SNPs) nos genes codificadores da IL-10, TNF-α e em NFkB1 e sua associação com parâmetros clínicos, laboratoriais e de seguimento de pacientes com linfoma de Hodgkin clássico

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Estudo da variabilidade da região codificadora e 3'não traduzida do gene HLA-F no Brasil

Pós-graduação em Patologia - FMB

Polimorfismos de nucleotídeo único (SNPs) nos genes codificadores da IL-10, TNF-α e em NFkB1 e sua associação com parâmetros clínicos, laboratoriais e de seguimento de pacientes com linfoma de Hodgkin clássico

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Estudo da variabilidade da região codificadora e 3'não traduzida do gene HLA-F no Brasil

Pós-graduação em Patologia - FMB

Complexo Epidendrum secundum como modelo de estudo multidisciplinar na delimitação de espécies

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)