976 resultados para national trial


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National Implementation Group (NIG) - European Working Time Directive & Non Consultant Hospital Doctors - Final Report December 2008  

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National Drugs Strategy 2009 – 2016 Click here to download PDF 2.6mb

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National Disability Strategy Towards 2016 Strategic Document Click here to download PDF 31kb

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  Annual Report of the Elder Abuse National Implementation Group (EANIG) 2007/2008 Click here to download PDF 2.0mb

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Actions of the National Drug Strategy 2009 – 2016 Click here to download PDF 512kb

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Palliative Care For Children With Life-Limiting Conditions In Ireland- A National Policy Click here to download PDF 1.30MB

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National Standards for Pre-School Services Click here to download PDF 168KB

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In Our Own Words: Report of the Consultation Process on the National Positive Ageing Strategy If you wish to receive this document in an alternative format, please email positiveageing@health.gov.ie or telephone 01-635 3184

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Growing Up in Ireland: National Longitudinal Study of Children. The Infants And Their Families – Infant Cohort Click here to download PDF 9.46MB   Click here to download the document summary 2.84MB

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This new cardiovascular policy, Changing Cardiovascular Health covering the period 2010-2019, comes a decade after the first national cardiovascular health strategy, entitled Building Healthier Hearts, was published by the Department of Health in 1999. The new policy is timely given the pace of scientific discovery and related changes in medical practice, changes in health service structures, and patterns and influences on population health behaviours in Ireland over the decade. Cardiovascular health and its maintenance is a microcosm of health more generally. A policy that can improve cardiovascular health and cardiovascular disease management will have beneficial effects for the whole healthcare system and population.Download this document

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National Policy and Strategy for the Provision of Neuro-Rehabilitation Services in Ireland 2011 – 2015 Click here to download PDF 1.51MB

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National Paediatric Hospital Independent Review Click here to download Overview of the Report PDF 403KB Click here to download National Paediatric Hospital Independent Review: Financial Analysis PDF 4.95MB Click here to download National Paediatric Hospital Independent Review: Financial Analysis Vol II: Appendices PDF 16.12MB Click here to download National Paediatric Hospital Independent Review: Clinical Analysis PDF 415KB Click here to download FAQs PDF 10KB

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Purpose: To evaluate the extent of quality of life (QoL) associated adverse events (AEs) following PRECISION TACE with DC Bead compared with conventional transarterial chemoembolisation (cTACE). Methods and Materials: 201 intermediate HCC patients were treated with DC Bead (PRECISION TACE) or conventional TACE (cTACE) with doxorubicin in the PRECISION V clinical study. 93 patients were treated with DC Bead and 108 Patients with cTACE every 2 months and followed up for 6 months. AEs were classified according to the South West Oncology Group criteria. QoL associated AEs were defined as alopecia, constipation, nausea, vomiting, pyrexia, chills, asthenia, fatigue, and headache. Results: The biggest difference in QoL associated AEs was for alopecia: 2 patients (2.2%) for DC-Bead versus 21 patients (19.4%) for cTACE. For other clinical symptoms, constipation (n=10; 10.8% vs. n=13; 12%), vomiting (n=10; 10.8% vs. n=14; 13.0%), pyrexia (n=16; 17.2% vs. n=26; 24.1%), chills (n=1; 1.1% vs. n=5; 4.6%), and headache (n=2; 2.2% vs. n=8; 7.4%) showed lower incidence in the DC Bead group versus cTACE. Nausea, n= 15; 13.9% (n=15; 16.1%) and fatigue, n=6; 5.6% (n=13; 14.0%) were lower for cTACE. Total dose of doxorubicin was on average 35% higher in the DC Bead group. Conclusion: Although patients in the DC Bead group received a higher doxorubicin dose, less QoL associated AEs were reported for this group. Alopecia, the most obvious outward sign of toxicity, was only reported in a tenth of DC Bead patients. Thus, PRECISION TACE with DC Bead improves quality of life associated adverse events.

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Alcohol plays a complex role in Irish society. It is associated with many aspects of Irish social and cultural life and is generally consumed for enjoyment, relaxation and sociability. The pub often plays an important role in community life and is an attraction for tourists. More broadly, alcohol plays a signifi cant role in the Irish economy by generating employment, tax income and export income.However, alcohol is no ordinary commodity. It has major public health implications and it is responsible for a considerable burden of health and social harm at individual, family and societal levels. Steering Group Report on a National Substance Misuse Strategy February 2012 Click here to download PDF 2.7mb