Síndrome das pernas inquietas: Diagnóstico e tratamento. Opinião de especialistas Brasileiros

This article contains the conclusions of the November 17-18, 2006 meeting of the Brazilian Study Group of Restless Legs Syndrome (GBE-SPI) about diagnosis and management of restless legs syndrome (RLS). RLS is characterized by abnormal sensations mostly but not exclusively in the legs which worsen in the evening and are improved by motion of the affected body part. Its diagnosis is solely based on clinical findings. Therapeutic agents with efficacy supported by Class I studies are dopamine agonists, levodopa and gabapentine. Class II studies support the use of slow release valproic acid, clonazepan and oxycodone. The GBE-SPI recommendations for management of SPI are sleep hygiene, withdrawal of medications capable of worsening the condition, treatment of comorbidities and pharmacological agents. The first choice agents are dopaminergic drugs, second choice are gabapentine or oxycodone, and the third choice are clonazepan or slow release valproic acid.

Detecção da produção de slime por estafilococos coagulase-negativa isolados de cateter venoso central

Slime production is an important virulence factor of coagulase-negative Staphylococcus spp., allowing them to attach to smooth surfaces of biomaterials, and it has been associated with infections of implanted medical devices. In the present study the production of slime capsules in 27 strains of coagulase-negative Staphylococcus was investigated by culture in Congo Red agar (77.7% positivity), spectrophotometric or microplate method (81.4% positivity) and scanning electron microscopy (88.9% positivity). The resistance of coagulase-negative strains of Staphylococcus to various antimicrobial agents was also determined by agar disk diffusion. The proportion of strains resistant to penicillin G, oxacillin, erythromycin, clindamycin and gentamicin among the slime-producing staphylococci was 88.9%, 70.4%, 81.5%, 66.7% and 59.2%, respectively; all of the coagulase-negative staphylococci were susceptible to vancomycin. The strains isolated from central venous catheters were identified by a conventional method and the API Staph system. The 27 coagulase-negative Staphylococcus strains were identified as: S. saprophyticus (3.7%), S. xylosus (7.4%), S. haemolyticus (14.8%), S. epidermidis (37.0%), S. warneri (14.8%), S. lugdunensis (7.4%), S. hominis (7.4%), S. schleiferi (3.7%) and S. chromogenes (3.7%). It can be concluded that in the most of the coagulase-negative Staphylococcus species there was an association between slime production, the nosocomial origin of the strains and reduced sensitivity to the antibiotics, suggesting a pathogenic potential in the hospital environment.

Efeitos de diferentes sistemas de cultivo in vitro sobre o crescimento de folículos pré-antrais isolados de ovários de fetos bovinos

The objective of this study is to use different in vitro culture systems of preantral follicles from Nelore breed bovine fetuses in the last gestation quarter. The evaluation of treatments considered the time of growth of isolated follicles. Preantral follicles were mechanically isolated and submitted to the individual culture, for 9 days, in media no supplemented or supplemented with fetal calf serum (FCS), bovine serum albumin (BSA) or synthetic defined supplement substitute of serum KnockoutSR (KNO). We have also evaluated the effects of collagen gel or fetal calf fibroblast monolayer as substratum for in vitro cultures. The increase on the follicular diameter was followed in the first day (0 h), at the 72 h, 144 h and 216 h. Considering cultures of isolated follicles, the results have shown that the association between media supplemented with FCS and collagen gel was significantly more efficient on the increase of the follicular diameter than other treatments. It is not still established a system of appropriate cultivation that sustains the differentiation and multiplication of the granular cells and that maintains the contact of the same ones with the oocyte to provide molecules and factors that supply the metabolic demand. We also understand that our results also represent another promising step on the search for the ultimate system of in vitro culture of preantral follicles from bovines.

Políticas para a retomada do crescimento: reflexões de economistas brasileiros

Prefacio de Renato Baumann

Relatório de pesquisa: avaliaçao dos critérios de sustentabilidade dos financiamentos apoiados pelos fundos constitucionais brasileiros

Incluye Bibliografía

Flexibilidade e segurança no mercado de trabalho: a busca da melhoria da proteçao social dos trabalhadores brasileiros

Incluye Bibliografía

A variedade léxica da língua espanhola em dicionários bilíngues espanhol-português para aprendizes brasileiros

Due to factors such as globalization and the demography of Hispanic countries, the Spanish language has influenced worldwide, especially since the last decade of the 20th century, mainly countries which are geographically close to Spanish American countries, such as Brazil. In this context, it is necessary to think of the linguistic variation of the Spanish language, in which we emphasize the lexical variation. As any language, Spanish has a colossal and wealthy lexicon with different varieties related to the characteristics from each region: history, culture, customs etc. This diversity influences the development, the amplification and the renewal of a language, as well as the teaching-learning process. Thus, we proposed to analyze the lexicon varieties of Spanish language entries in some Spanish-Portuguese bilingual dictionaries for Brazilian learners. In order to achieve this goal, we selected some examples of lexical variety in a corpus organized with texts of different textual genres and we verified if these lexical items are registered in the dictionaries chosen. As the corpus is organized from texts present in didactic manuals used in Brazil, our goal is to verify if the vocabulary which the Brazilian learner has contact in formal education is registered in the analyzed dictionaries.

Estimativa de alguns parâmetros de transporte de contaminantes para solos Brasileiros

This paper introduces an indirect estimate for the coefficients of distribution, hydrodynamic dispersion and retardation for contaminants commonly encountered in sanitary landfills and their liners, such as Cu2+ and K+; this estimate is based on the relationship between concentration and certain physical characteristics of typical Brazilian soils. The results of previous studies investigating the migration of contaminants were used to develop mathematical expressions from multiple non-linear regressions. Using minimal squares regression, this transport was linked to various combinations of contaminant concentration and both structural and textural characteristics of the porous medium. Various combinations of characteristics and concentrations were investigated, with a mathematical expression obtained for each. The relationship between percentage of clay and the contaminant content proved to be the most closely correlated with actual transport parameters, with coefficients close to one.

Perfil de resistência a antimicrobianos de Staphylococcus aureus isolados de granjas e frigoríficos de suínos

Staphylococcus aureus are involved in a wide range of clinical problems to swine industry as son in humans. Epidemiological researchs prove his potential to acquire resistantence to antibiotics. Nowadays, methicillin-resistant S. aureus (MRSA) are responsabilized for nosocomial infections and many studies are done because MRSA are spread to extra hospitalar enrivonment and frequentely isolated from domestic animals including pigs. The aim of this study was to determine the presence o S. aureus at swine farms and identify the mecA, icaA and icaD genes and the resistant proflife to antibiotics. Overal, 458 swabs were taked from five pigeris and two slautherhouses. All the samples were placed on Braid - Parker and blood agar follow by biochemical analyses. The suspect colonies were submitted to PCR to confirm the S. aureus species, by the detection of the coa gene, mecA to avaible meticillin-resistant as son to the virulence gens icaA and icaD that can determine slime production. Antibiogram were done to evaluate the response to 11 antibiotics. All pigeris and slautherhouse were positive and 81 (79%) samples were S. aureus positive including four isolates from pigs employeers. The mecA gene was not detected. The icaD gene was most frequent and 41% were positive to both genes. The antibiogram show a lot of samples penicillin and tetraciclin resistant. Most of the samples were multirestant.

Seleção de isolados de beauveria bassiana (Bals.) Vuill. para o controle de sitophilus zeamais (Mots.) (Coleoptera: Curculionidae)

Sitophilus zeamais (Mots.) (Coleoptera: Curculionidae) is considered a major pest of maize, responsible for reducing grain quality and making the corn inappropriate for industrial use and human consumption. S. zeamais has been controlled exclusively with chemical products. The objective of this research was to select isolates of Beauveria bassiana (Bals.) Vuill. to control S. zeamais. Beetles were immersed in conidia suspensions of each isolate for five seconds and placed in a gerbox container with maize grains. In pathogenicity tests, the isolates that caused the highest mortality to the maize weevil were ESALQ-447 (68.0%), CCA-UFES/ Bb-36 (57.3%) and CCA-UFES/Bb-31 (51.3%). ESALQ-447 was the most virulent, with an LC50 of 1.7 × 107 conidia/ml and shows promise for controlling maize weevils. These isolates of B. bassiana can be used as effective substitutes for conventional chemical control, normally carried out with phosphine. Further tests should be performed under field and semi-field conditions to develop an appropriate strategy for the use of this entomopathogen to manage S. zeamais.

Brasileiros Ilustres: Letras, armas, virtudes

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

Características aeróbias e anaeróbias de mesatenistas brasileiros treinados

O objetivo deste estudo foi determinar, em mesatenistas bem treinados, as aptidões aeróbia e anaeróbia. Participaram do presente estudo oito mesatenistas brasileiros treinados do sexo masculino (18±2 anos). Os sujeitos foram submetidos a um teste incremental específico para determinação do consumo pico de oxigênio (VO2PICO), intensidade associada ao VO2PICO (iVO2PICO) e do ponto de compensação respiratório (PCR) e a dois testes de esforço repetitivo, sendo o teste de RAST e o índice anaeróbio alático (IAA), para determinação dos índices anaeróbios. O VO2PICO correspondeu a 50,5±4,4ml kg-1 min-1 , a iVO2PICO a 52,1±9,6 bolas min-1 e o PCR a 44,9±8,0 bolas min-1. No RAST, a potência pico (PP) e a potência média (PM) relativa corresponderam a 9,0±1,3W kg-1 e 7,0±0,9W kg-1, respectivamente, enquanto que o IAA foi 1,14±0,51 mM/m s-1 . Esses valores de VO2PICO e dos parâmetros anaeróbios quando comparados a valores de outros esportes com raquetes caracterizaram que mesatenistas brasileiros treinados apresentam potência aeróbia moderada e potência anaeróbia é baixa.

Análise conformacional dos petídeos protonectina e protonectina (1-6), isolados e em associação, em mistura TFE-água

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Análise morfométrica comparativa e biogeografia dos pequenos Artibeus brasileiros Leach, 1821 (Mammalia, Chiroptera, Phyllostomidae)

Pós-graduação em Biologia Animal - IBILCE