996 resultados para annual efficiency
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Annual report for the Iowa Citizens’ Aide/Ombudsman Office.
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Annual report for the Iowa Citizens’ Aide/Ombudsman Office.
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Annual report for the Iowa Citizens’ Aide/Ombudsman Office.
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Annual report for the Iowa Citizens’ Aide/Ombudsman Office.
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The Iowa Watershed Improvement Review Board (WIRB) was created by the Iowa Legislature and signed into law by the Governor in 2005 as Senate File 200. This statute is now codified in Iowa Code Chapter 466A. The fifteen-member Board conducted eight meetings throughout the year in-person or via teleconference. Meetings were held January 24, February 27, March 13, May 15, August 7, September 20, October 6, and December 18. Attachment 3 lists the board members and their organization affiliation. The Board appointed a five-member subcommittee to review and revise the Request For Applications (RFA) documents and submit recommendations to the full Board. The RFA documents were approved as modified at the May 15, 2006 Board meeting.
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ICRC works to promote safe, just, and inclusive communities. Safe and inclusive communities are free from discrimination and free from loss of dignity and humanity. Civil rights enforcement helps ensure society receives full benefits of a diverse and inclusive workforce and reduces economic losses from discrimination. To prevent problems and provide a more welcoming economic climate, our agency educates business and industry on civil rights laws and diversity concerns.
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Annual Report for Iowa Vocational Rehabilitation Services (IVRS), a division of the Iowa Department of Education, is committed to working for and with individuals who have disabilities to achieve their employment, independence and economic goals. This document contains information highlighting the accomplishments of IVRS this year.
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Recombinant human tumour necrosis factor (TNF) has a selective effect on angiogenic vessels in tumours. Given that it induces vasoplegia, its clinical use has been limited to administration through isolated limb perfusion (ILP) for regionally advanced melanomas and soft tissue sarcomas of the limbs. When combined with the alkylating agent melphalan, a single ILP produces a very high objective response rate. In melanoma, the complete response (CR) rate is around 80% and the overall objective response rate greater than 90%. In soft tissue sarcomas that are inextirpable, ILP is a neoadjuvant treatment resulting in limb salvage in 80% of the cases. The CR rate averages 20% and the objective response rate is around 80%. The mode of action of TNF-based ILP involves two distinct and successive effects on the tumour-associated vasculature: first, an increase in endothelium permeability leading to improved chemotherapy penetration within the tumour tissue, and second, a selective killing of angiogenic endothelial cells resulting in tumour vessel destruction. The mechanism whereby these events occur involves rapid (of the order of minutes) perturbation of cell-cell adhesive junctions and inhibition of alphavbeta3 integrin signalling in tumour-associated vessels, followed by massive death of endothelial cells and tumour vascular collapse 24 hours later. New, promising approaches for the systemic use of TNF in cancer therapy include TNF targeting by means of single chain antibodies or endothelial cell ligands, or combined administration with drugs perturbing integrin-dependent signalling and sensitizing angiogenic endothelial cells to TNF-induced death.
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This document is the State of Iowa's Annual Performance Report (APR) for the period beginning January 1, 2006 and ending December 31, 2006 (Program Year 2006). This report is intended to fulfill the U.S. Department of Housing and Urban Development (HUD) requirements that require the state to annually review and report the progress made in carrying out its Consolidated Plan for Housing and Community Development. This report, and the supplemental documentation included with it, replaces several year end reports submitted individually in the past.
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Annual report for the Iowa Racing and Gaming Commission of Iowa.
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Annual report for the Iowa Racing and Gaming Commission of Iowa.
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Annual report for the Iowa Racing and Gaming Commission of Iowa.
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Annual report for the Iowa Racing and Gaming Commission of Iowa.
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Annual report for the Iowa Racing and Gaming Commission of Iowa.
