994 resultados para Reconstituição imune


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The effect of physical exercise in immune function has been extensively studied. The intensity and duration of physical exercise have considerable influence in immunologic parameters. However, few studies have compared different exercise intensities in different stages of a physical training program. Thus, the aim of this study was to verify the metabolic, hormonal and immunologic changes before and after acute intermittent swimming exercise, following different stages of training program. Seventeen male swimmers were evaluated in three stages of training. The intensity of the three sessions was 90% (anaerobic potency – PAN), 70% (aerobic potency - PAE) and 98% (lactate tolerance – TLA) of the maximal speed from the best time of the distance, resulted from peak performance in competition. Blood samples were collected pre and immediately after exercise for cells counting and measurement of substrates and cortisol concentrations. It was used ANOVA to verify the significance of difference (p<0.05). There was a significant increase of glucose and cortisol post exercise in the PAN and PAE sessions. Glutamine increased significantly in PAE and TLA. Leukocytes increased significantly after the three different sessions and lymphocytes decreased significantly on PAE and TLA. In conclusion, it was demonstrated that changes of the several parameters studied in different stages of training program can cause temporary alterations in immune cells and may compromise resistance to common minor illnesses and athlete performance.

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The main function of the immune system is the defense against infection, being composed by the leukocytes that modulate the immune response, which can be innate or adaptive. The physical exercise can causes positive or negative alterations in the total or relative number of leukocytes. When the exercise has a low or moderate intensity it`s considered beneficial for improving the function of the cells responsible for the defense and to reduce the risk of infectious illnesses. The type 2 diabetes is related to an incapacity of the body in rightly respond to insulin, associated to an resistance to its actions. The purpose of this research was to make a study of the immune system characteristics, as well as the type 2 diabetes and the relation among both and the physical exercise. So, it was analyzed a group of type 2 diabetics coming from Diabetics House of Franca -SP, treated through a program of mix physical training. Two collections of blood were pre and post training program for the pair comparable of the participants. It was found positive alterations of the subpopulations of leukocytes that show a probable improvement of the immunological state what allows us to suggest about a possible improvement of the immunological activity, what would be measured by the activation of these cells forward to an inflammatory/infectious condition. So, we suggest that future studies involving diabetes, immune system and physical exercise be encouraged.

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Pós-graduação em Engenharia Elétrica - FEIS

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Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

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Pós-graduação em Pesquisa e Desenvolvimento (Biotecnologia Médica) - FMB

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Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

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Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

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Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

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Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

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Pós-graduação em Doenças Tropicais - FMB

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Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

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The Areado Group of the Sanfranciscana Basin is a Lower Cretaceous continental sedimentary system that is correlated to the Brazilian Pre-Salt beds. The Aerado Group is composed of Abaeté, Quiricó and Três Barras formations. Paleocurrent data for the Areado Group were previously presented, although not systematically which prevented significative interpretations on the basin paleogeography. This work attempts to systematically evaluate paleocurrent data, aiming to recognize depositional environment and paleogeographic reconstruction, based on the sedimentary facies and paleocurrents measurements along vertical profiles. Fluvial paleocurrents of the Abaeté Formation indicate paleoflows towards NW whereas aeolian palecurrents of the Três Barras Formation show paleowinds towards SW. The depositional systems interpreted for the Areado Group were: braided river, alluvial fan, lacustrine, playa lake, fluvial-deltaic and aeolian. The combined analyses of facies and paleocurrents allowed a reliable paleogeographic reconstruction of the basin, with paleodip towards northwest, paleowinds towards south-southwest and source-area located at southeast. These results indicate that paleowinds were orthogonal to paleostream, but parallel to depositional strike of the basin. The interpreted depositional systems characterize a desert environment during the Abaeté sub-basin times. The association of dunes and wet interdunes followed by large scale dunes and dry interdunes suggests a decrease in humidity towards the top of the Três Barras Formation, with a dry aeolian system onlapping the basement. The observed decrease of humidity in Sanfranciscana Basin may reflect local or regional paleoclimatic changes during the opening of the South Atlantic, but this assumption is only tentative

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Pós-graduação em Medicina Veterinária - FCAV