Candida dubliniensis: prevalência na cavidade bucal de pacientes diabéticos, com câncer de mama e hansenianos e patogenicidade experimental

O objetivo deste estudo foi avaliar a presença de C. dubliniensis dentre isolados bucais de pacientes com Diabetes mellitus do tipo I (n=39) e II (n=36), hansenianos (n=38) e sob quimioterapia para o câncer de mama (n=30) e de respectivos indivíduos controle pareados quanto à idade, gênero e condições bucais. Um total de 479 isolados previamente identificados por testes fenotípicos (formação de tubo germinativo, produção de hifas/pseudohifas/clamidoconídeos, fermentação e assimilação de carboidratos) e identificadas como C. albicans/C. dubliniensis foram incluídos no estudo. A existência de C. dubliniensis dentre os isolados foi analisada usando protocolo validado de PCR multiplex. Foi também realizado estudo de patogenicidade experimental utilizando camundongos em modelo de infecção sistêmica, objetivando comparar a virulência e cinética de infecção de C. dubliniensis com outras espécies do gênero Candida. Um isolado (0.002%) de C. dubliniensis foi detectado entre os isolados do grupo controle. Esta espécie não foi encontrada dentre os isolados dos outros grupos de pacientes. C. dubliniensis foi menos virulenta para camundongos em relação a C. albicans e C. tropicalis e mais virulenta do que C. krusei. O estudo da cinética de infecção mostrou infecção persistente no rim e no fígado mesmo após 21 dias da inoculação de C. dubliniensis. Conclui-se que a detecção de C. dubliniensis dentre os isolados clínicos foi baixa e observada apenas no grupo controle. C. dubliniensis foi menos virulenta para camundongos que C. albicans e C. tropicalis e causou infecção prolongada no rim e no fígado

Prevalência de perdas urinárias em uma amostra de mulheres de Botucatu

Pós-graduação em Ginecologia, Obstetrícia e Mastologia - FMB

Prevalência e fatores de risco para carreamento de Staphylococcus aureus resistente à meticilina em idosos institucionalizados na cidade de Bauru-SP

Pós-graduação em Doenças Tropicais - FMB

Análise da prevalência e de fatores de risco para as hepatites virais crônicas B e C em idosos residentes no município de Botucatu-SP

Pós-graduação em Fisiopatologia em Clínica Médica - FMB

Prevalência de Streptococcus suis sorotipo 2: discussão da literatura brasileira

Streptococcus suis is considered worldwide as one of the pathogens of biggest health and economic impact in the swine industry. Among the serotypes described as zoonotic, serotype 2 is the most frequently isolated from diseased animals and humans in most countries. The study of the epidemiology of S. suis infections in Brazil is important and may help in the development of effective control measures. The aim of this study was to conduct a critical review of Brazilian literature, with support of the world literature, addressing the diagnosis of the agent and its prevalence in clinically ill animals and healthy carriers, especially regarding to the prevalence of the serotype 2 in the country.

Prevalência de hábitos de sucção não nutritivos em pré-escolares e a percepção dos pais sobre sua relação com maloclusões

Este estudo transversal e descritivo objetivou verificar a prevalência de hábitos de sucção em pré-escolares e a percepção dos pais sobre a relação com a ocorrência de maloclusões. A população do estudo constituiu-se por uma amostra representativa de pais de pré-escolares de 4 meses a 6 anos de idade. Utilizou-se um questionário semiestruturado, composto por questões abertas e fechadas, referentes à frequência e conhecimentos dos pais frente aos hábitos de sucção não nutritivos. Dos 356 participantes da pesquisa, 70,8% afirmaram que as crianças apresentavam algum hábito bucal, sendo a sucção de chupeta o mais frequente (45,6%). Apesar da grande maioria dos pesquisados (97,1%) relatarem saber que os hábitos podiam causar prejuízo aos dentes, 70,2% deles já haviam oferecido chupeta à criança, na maioria das vezes para acalmá-la (61,8%). Houve associação estatisticamente significativa entre a oferta da chupeta à criança e o conhecimento sobre a relação da presença de hábitos não nutritivos e a ocorrência de maloclusão (p < 0,0001 e Qui-quadrado = 60,123). A prevalência de hábitos bucais na população estudada é alta e, apesar da maioria dos pais saberem que o hábito de sucção de chupeta pode causar danos à saúde bucal, ofertavam a chupeta a fim de acalmar a criança.

Diferentes técnicas de diagnóstico empregadas na estimativa de prevalência populacional de infecção por Cryptosporidium felis em gatos domiciliados no município de Araçatuba, São Paulo

Pós-graduação em Medicina Veterinária - FCAV

Prevalência de Mycoplasma bovis em rebanhos de vacas leiteiras do interior do estado de São Paulo

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Estudo clínico de prevalência de sinais e sintomas de disfunções craniomandibulares e contatos oclusais cêntricos em pacientes portadores de lesão labiopalatal

A clinical investigation was undertaken to find out the prevalence of craniomandibular signs and symptoms in a group of 11 patients with labiopalatal lesions. The number and distribution of occlusal contacts was evaluated through questionnaire, clinical examination and analysis of mounted casts in partially adjustable articulators in the position of maximum inter cuspation. The most frequent signs and symptoms were articular sounds and lateral pterygoid muscle tenderness to palpation followed by restriction of mouth opening and sensation of tiredness. The number of occlusal contacts was small, mean of 5 contacts per patient, and the site was considered as atypical, 62% of them were on inclined plane surfaces , suggesting occlusal instability. The frequency of signs and symptoms was low and they were of a mild character. The most prevailing signs of craniomandibular dysfunction - articular sounds, muscular tenderness to palpation and restriction of mouth opening - was noticed in only one of the patients

Estudo da prevalência de disfunção craniomandibular segundo o índice de Helkimo tendo como variáveis: sexo, faixa etária e indivíduos tratados ou não ortodonticamente

One hundred non-patient dentistry students aged 17 to 25, were interviewed through questionnaire and were clinically examined in order to asses the prevalence and degree of severtty of Craniomandibular Dysfunction, through indeces which are subdivided into three classes: anaminestic index, clinical dysfunction index, and occlusal index. The following variables were introduced to the original indeces: sex, age, and whether the subjects had or had not received orthodontic treatment. The results showed that 42% of the subjects presented mild subjective symptoms whereas, no one showed severe subjective symptoms. Women, as well as the older subjects, showed a higher trend to presenting more subjective complaints. Subjects, whether treated orthodontically or not, showed a similar trend to having dysfunction symptoms. Fifty-six per cent of the subjects presented some score of clinical dysfunction, 25% of them showed moderate or severe clinical dysfunction. Women showed a statistically significant higher index. The older subjects trented to have indeces with more severe degrees. Orthodontic treatment suggested to have no influence on the clinical dysfunction index. Sixty-six per cent of the subjects showed a mild occlusal index and 11% a severe occlusal index. Sex, age, and orthodontic treatment did not show any significant difference as to the presence or absence of malocclusion

Prevalência da baixa densidade mineral óssea em mulheres na pós-menopausa tratadas de câncer de mama

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Prevalência e fatores de risco para brucelose suína em Mossoró-RN

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Prevalência de Clostridios sulfito redutores e Clostridium perfringens na mucosa intestinal de frangos de corte

Pós-graduação em Microbiologia Agropecuária - FCAV

Prevalência do uso de chupeta e conhecimento dos educadores numa escola de educação infantil: estudo piloto

Pacifier use is very common among children, but despite being considered a harmless article, there is ample evidence of their misdeeds. Therefore, concern about its use is great for us who work in the promotion of breastfeeding. It is this delicate subject in schools because the child, in most cases, already goes to school with the habit installed. The pacifier use may interfere with speech aspect, because the child can come to the wrong talk, dental, dental occlusions, may cause bacterial contamination and encourage early weaning. The aim of this study was to investigate the prevalence of pacifier use among children of pre - school and knowledge of educators about the role of pacifier and its consequences. The research methodology was based on a questionnaire to teachers, monitors and direction and determine the prevalence of pacifier use with parents. According to the result, we developed an orientation for school. The results show that of the 57 children at the age of 4 months to 3 years, 50.88% used a pacifier, 92.98% and 96.49% used the bottle were breastfed. The guidance given after the data collection has clarified many questions for educators. We conclude that the methodology was effective because we can collect data addressing quantitative and qualitative questions and managed to get percentages on pacifier use and breastfeeding and student opinions, comments and more relevant phrases that emerged from parents and educators, complementing the result. Furthermore, through the data, it was possible to do an intervention. The results indicate that half of the children between 4 months and 3 years investigated makes use of a pacifier, so despite the advice given, it would be important to follow up these data over the next few years. We also conclude that a partnership is needed between parents and the school, because if the family does not help, you can not work in school guidance

Prevalência da excreção e caracterização molecular do poliomavírus humano JC em amostras de urina de pacientes com aids sem leucoencefalopatia multifocal pro-gressiva

The human poliomavirus is the etiologic agente of Progressive multifocal leukoencephalopathy (PML), a disease characterized by focal lesions not expansives of the central nervous system that develops in imunocompromissed patients, specially people with aids. The main aim of the study was to evalute the prevalence of the JCV excretion in urine samples of patients with aids, without PML, to compare two JCV DNA detection techniques through of two diferents genomic regions and to evaluate the genotypic characterization of the positive samples. A total of 75 samples were colected in the Instituto de Infectologia Emílio Ribas, in Sao Paulo, Brazil, between may and november, 2009. To detect the JC virus it was made the DNA extraction and then the polimerase chain reaction (PCR). Firstly a fragment of 215 bp was amplified, which corresponds to the codifying gene of the strutural protein of de JC vírus capsid VP1. All the samples were later submitted to another PCR that uses a pair of primers complementaries to the early region of the JCV (T antigen) amplifying a fragment of 173 bp. Followed by the digestion of the amplified product with the restriction enzime BamH1, resulting in two smaller fragments (120 bp and 53 bp). The JC vírus was detected in 53 samples, for both techniques (70,7% for VP1 PCR, and the restriction enzime BamH1), 34/46 were men (73,9%) and 19/29 were women (65,5%). The JCV excretion was higher in individuals that were over 46 years old. Regarding the seven genotypes described in the literature, the ones that were more prevalent among the JC positive patients were 3B and 3A with 10 samples each (21,0%), the 2B with 9 samples (19,0%) and genotype 6, with six samples (13,0%). As in the brown patients as the white ones, the most prevalent genotype was 3B. In the present study it was observed a high prevalence of JCV DNA (70,7%) and the genotype 3 (43,0%)... (Complete abstract click electronic access below)