Non-alcoholic fatty liver disease and its associated risk factors in Brazilian postmenopausal women

Objective To evaluate the prevalence and risk factors of non-alcoholic fatty liver disease (NAFLD) in postmenopausal women.Methods A cross-sectional study was carried involving 188 women (age >= 45 years and amenorrhea >= 12 months) attending the outpatient unit in south-eastern Brazil. Exclusion criteria were liver disease (hepatitis B and C, cholestatic disease, liver insufficiency), use of drugs that affect liver metabolism; alcoholics; AIDS or cancer history; and morbid obesity. NAFLD was diagnosed by abdominal ultrasound. Clinical, anthropometric (body mass index, waist circumference) and biochemical variables were measured.Results Of the 188 women, 73 (38.8%) had NAFLD. Blood pressure, waist circumference, body mass index, LDL cholesterol, triglycerides and glucose were significantly higher in NAFLD patients when compared with women without NAFLD (control group) (p < 0.05). HOMA-IR values indicated insulin resistance only in the NAFLD group (6.1 +/- 4.6 vs. 2.4 +/- 1.4 in control group, p < 0.05). Metabolic syndrome was detected in 93.1% of the women affected by NAFLD, and 46.1% of the control group (p < 0.05). In multivariate analysis, adjusted for age and weight, the variables considered at risk for the development of NAFLD, were: high waist circumference (odds ratio (OR) 1.07, 95% confidence interval (CI) 1.01-1.13), insulin resistance (OR 3.81, 95% CI 2.01-7.13), and presence of metabolic syndrome (OR 8.68, 95% CI 3.3-24.1).Conclusion NAFLD showed a high prevalence among postmenopausal women. The presence of metabolic syndrome, abdominal obesity and IR were indicators of risk for the development of NAFLD.

ASIAN SOYBEAN RUST INTEGRATED MANAGEMENT POTENTIAL: DISEASE SEVERITY, PLANT DEVELOPMENT AND YIELD COMPONENTS, CULTIVAR MG/BR-46 (CONQUISTA)

Soybean rust caused by Phakopsora pachyrhizi Sydow & P. Sydow is one of the major diseases of the soybean crop. The aim of this study was to evaluate the effects of sowing dates, plant populations and reduced doses of fungicides on soybean rust severity and its effects on plant development and yield, cultivar MG/BR46 (Conquista). Field experiments were conducted in the 2009/2010 and 2010/2011 harvests, under natural rust infestation of soybean rust. As from the appearance of the first disease symptoms, also began the fungicide spraying and the disease severity assessments. To understand the nature and extent of the effects of different treatments, a multivariate analysis of factors was applied. For the majority of the agronomic characters and factors, one-third to two-thirds of their variability can be explained by changes in plant populations or by differences in the fungicide treatments, and the remainder, was explained by sowing date variations. The fungicide treatments and sowing dates are determinants in disease severity and its interference on crop productivity. The characters of plant growth are more dependent on plant population variations. Treatments with azoxystrobina + ciproconazol promoted smaller disease severities, reflecting in productivity increase. The plant populations can be reduced up to 160.000 plants ha(-1) without losses in the disease control and the soybean yield. In general, the earliest sowings provided increase in the plant development, although the rust control was less efficient.

Habilidades Sociais e Dependência Nicotínica em Universitários Fumantes

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Metaloproteinases de matriz 2 e 9 no líquido cefalorraquidiano e soro de cães naturalmente infectados pelo vírus da cinomose

Pós-graduação em Medicina Veterinária - FCAV

Epidemiologia da infecção por Leptospira spp. em áreas rurais nos biomas brasileiros

Pós-graduação em Medicina Veterinária - FCAV

Qualidade e erodibilidade de latossolos sob mata e cultivo de cana-de-açúcar

Pós-graduação em Agronomia (Ciência do Solo) - FCAV

Neoplasias mamárias de cadelas: expressão gênica e proteica da via Wnt/b-catenina, sua associação com a transição epitélio-mesênquima e prognóstico

Pós-graduação em Medicina Veterinária - FCAV

Definição de um modelo de análise de sucesso das empresas baseado em índices contábeis e na análise multivariada

The objective of this paper is to relate the set of financial ratios that are directly related to the success of public traded companies using a methodological approach and the method of multivariate principal component analysis. This study consists in the use of profitability ratios, debt and liquidity, to define the relationship between financial ratios with the best public traded companies listed in the magazine Exame Melhores e Maiores of 2013. Multivariate analysis was used to reduce the dimensionality of multivariate data, making linear combinations of the original variables (financial ratios) and express the data in principal components that result in new variables that contains much of the original data. As a result, we got the optimal number of five principal components, and both represent 95.6% of the original data. Among of all financial ratios, we can highlight the direct relationship between profitability ratios for the first principal component, and the direct relationship between the liquidity ratios, both inversely related with non-capital participation rates and degree indebtedness to the second principal component

Avaliação de genótipos de cártamo quanto ao desempenho agronômico, divergência genética e produtividade da água

Pós-graduação em Agronomia (Agricultura) - FCA

Aplicação da análise fatorial em cidades do Vale do Paraíba considerando os objetivos do milênio

Pós-graduação em Engenharia Mecânica - FEG

Avaliação da prevalência das doenças peri-implantares e do sucesso e sobrevivência de implantes osseointegrados com 8 a 10 anos de função

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Avaliação da obesidade na prevalência e gravidade das disfunções temporomandibulares

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Impacto da construção de Pequenas Centrais Hidrelétricas (PCHs) sobre a comunidade de macroinvertebrados aquáticos associados a pedrais: um estudo de caso no rio Sapucaí-Mirim (SP)

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Síndrome de Burnout em cirurgiões-dentistas com diferentes atuações profissionais

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Perception of Risk of Musculoskeletal Disorders Among Brazilian Dental Students

The aim of this study was to compare the mean scores of perceived risk factors for the development of musculoskeletal disorders in dental students presently pursuing work/study, according to gender, course series, and the presence of pain/discomfort. The participants were 348 students from the undergraduate course in dentistry at a Brazilian public university. The instrument on work-related factors that could contribute to osteomuscular symptoms and part of the Nordic questionnaire were used. The psychometric properties of the first instrument were estimated. A multivariate analysis of variance (MANOVA) revealed that the instrument had a tri-factorial structure (s2 retained: 62.72 percent). The retained factors were repetitiveness, work posture, and external factors. The internal consistency and reproducibility were adequate (α=0.746 to 0.873; p=0.729 to 0.940). Lower mean scores of perceived external factors were observed for the male participants, as well as lower scores in the three dimensions of the instrument for first-year students of the course and for those who did not report pain/discomfort in the neck, feet, and ankles. The authors concluded that the perception of risk factors for musculoskeletal disorders reported in the work/study environment of dental students was significantly related to gender, the course series, and the presence of pain/discomfort.