The last Anthracothere Brachyodus onoideus (Mammalia, Artiodactyla) from westernmost Europe and its extinction

This paper deals with B. onoideus specimens from Portugal. This species occurs in the Lisbon area (in the upper part of the lower Miocene, ca.18 to 17.6 Ma) in a very accurate stratigraphic framing (age, lithostratigraphic, climatic and palaeoecologic control being most complete). Some mandibular dental size variation, sex characters, functional interpretation, ecology and predation, chemical corrosion, and extinction are discussed.

Controlo da compactação com recurso a gamadensímetro – Caso de estudo: ETAR de Castelo Branco

Mestrado em Engenharia Geotécnica e Geoambiente

Information professionals in business context: new professionals, old skills

This communication aims to present some reflections regarding the importance of information in organizational context, especially in business context. The ability to produce and to share expertise and knowledge among its employees is now a key factor in the success of any organization. However, it’s also true that workers are increasingly feeling that too much information can hurt their performance. The existence of skilled professionals able to organize, evaluate, select and disseminate information in organizations appears to be a prerequisite for success. The skills necessary for the formation of a professional devoted to the management of information and knowledge in the context of business organizations will be analysed. Then data collected in two focus group discussion with students from a graduate course in Business Information, from Polytechnic Institute of Porto, Portugal, a will be examined.

Expression of antibodies and retroviralVectors from defined chromosomal sites: strategies towards reliable production systems

Dissertation presented to obtain a Ph.D. degree in Sciences of Engineering and Technology, Cell Technology, at the Instituto de Tecnologia Química e Biológica, Universidade Nova de Lisboa

Sistemas de fachadas em perfilaria de alumínio, painel compósito em Alucobond e estruturas metálicas

A memória descritiva do estágio transcreve e revela os conhecimentos adquiridos ao longo do curso e aplicados ao longo do estágio, bem como todos aqueles obtidos e aperfeiçoados no estágio, nomeadamente no que espeita a planeamento, controlo de custos, aprovisionamento, preparação dos materiais e elaboração de autos de medição. Para um melhor aprofundamento destes conceitos, foi proposto pela empresa, o acompanhamento técnico de duas obras, contudo, ambas distintas quer ao nível de materiais e execução. Primeiramente, é feita uma pequena apresentação da empresa assim como uma descrição global das duas obras que foram propostas pela empresa, para fazer o acompanhamento técnico ao longo do estágio Apresentados os traços gerais do estágio é realizada uma pequena exposição teórica dos dois principais elementos, alumínio e aço, constituintes dos principais materiais utilizados nas duas obras em acompanhamento, indicando alguns dados sobre o seu modo de produção e caracterização física e mecânica. Nos dois capítulos seguintes faz-se uma descrição dos principais trabalhos realizados em ambas as obras. Na obra da rua Alfredo do Guisado são enunciados todas as tarefas da produção e da preparação em oficina para aplicação em obra de uma fachada ventilada em painel compósito de Alucobond. No que respeita a obra da Caetano Parts é feito o enquadramento do acompanhamento técnico em todas as tarefas desempenhadas pelas oficinas, descrevendo todos os processos envolvidos desde a preparação, aprovisionamento, tratamento e montagem dos diferentes materiais em obra. Por fim, são apresentadas algumas considerações finais do estágio desenvolvido.

Sistema para a monitorização ativa com recurso ao cloud computing

O desenvolvimento de aplicações para dispositivos móveis já não é uma área recente, contudo continua a crescer a um ritmo veloz. É notório o avanço tecnológico dos últimos anos e a crescente popularidade destes dispositivos. Este avanço deve-se não só à grande evolução no que diz respeito às características destes dispositivos, mas também à possibilidade de criar aplicações inovadoras, práticas e passíveis de solucionar os problemas dos utilizadores em geral. Nesse sentido, as necessidades do quotidiano obrigam à implementação de soluções que satisfaçam os utilizadores, e nos dias de hoje, essa satisfação muitas vezes passa pelos dispositivos móveis, que já tem um papel fundamental na vida das pessoas. Atendendo ao aumento do número de raptos de crianças e à insegurança que se verifica nos dias de hoje, as quais dificultam a tarefa de todos os pais/cuidadores que procuraram manter as suas crianças a salvo, é relevante criar uma nova ferramenta capaz de os auxiliar nesta árdua tarefa. A partir desta realidade, e com vista a cumprir os aspetos acima mencionados, surge assim esta dissertação de mestrado. Esta aborda o estudo e implementação efetuados no sentido de desenvolver um sistema de monitorização de crianças. Assim, o objetivo deste projeto passa por desenvolver uma aplicação nativa para Android e um back-end, utilizando um servidor de base de dados NoSQL para o armazenamento da informação, aplicando os conceitos estudados e as tecnologias existentes. A solução tem como principais premissas: ser o mais user-friendly possível, a otimização, a escalabilidade para outras situações (outros tipos de monitorizações) e a aplicação das mais recentes tecnologias. Assim sendo, um dos estudos mais aprofundados nesta dissertação de mestrado está relacionado com as bases de dados NoSQL, dada a sua importância no projeto.

Traumatic Clivus Epidural Hematoma: Case Report and Review of the Literature

BACKGROUND: Traumatic clival epidural hematoma is an extremely rare reported entity. CASE DESCRIPTION: We describe the case of a 26-year-old woman involved in a car accident who presented with a Glasgow Coma Scale score of 13, bilateral abducens palsy, bilateral numbness on the mandibular territory of the trigeminal nerve, and left hypoglossal palsy. Radiological examinations revealed a clival epidural hematoma. The patient was managed conservatively, with clinical improvement of her neurological condition. This is the first traumatic clival epidural hematoma reported in an adult. From a review of the literature, we found only 8 cases. CONCLUSION: The pathophysiology of these hematomas is still a subject of debate; occipitoatlantoaxial ligamentous instability may play a role in it. In one third of the cases, bilateral cranial nerve palsies were associated. Apparently, they have a benign outcome.

Information professionals in business context: new professionals, old skills

This communication aims to present some reflections regarding the importance of information in organizational context, especially in business context. The ability to produce and to share expertise and knowledge among its employees is now a key factor in the success of any organization. However, it’s also true that workers are increasingly feeling that too much information can hurt their performance. The existence of skilled professionals able to organize, evaluate, select and disseminate information in organizations appears to be a prerequisite for success. The skills necessary for the formation of a professional devoted to the management of information and knowledge in the context of business organizations will be analysed. Then data collected in two focus group discussion with students from a graduate course in Business Information, from Polytechnic Institute of Porto, Portugal, a will be examined.

Cirurgia de Reparação Mitral em Crianças com Valvulopatia Adquirida

BACKGROUND: Valve surgery in children is aimed at restoring correct hemodynamics with few reoperations and limited resort to prostheses, which would imply early deterioration or definitive hypocoagulation. OBJECTIVES: Report a series of paediatric pts with acquired mitral valve disease, mostly due to rheumatic disease, in whom it was possible, for the great majority, to repair the damaged valve. DEMOGRAPHICS: Fifty children with predominant mitral valve disease, 47 rheumatic (94%) and 3 after endocarditis were consequently operated by the same surgical team over the last five years. Ages were 12.5+/-3.1 yrs and weights 33.2+/-8.4 Kg, 30 pts presented with predominant mitral regurgitation and 20 pts had significant stenosis. In 8 pts there also moderate to severe aortic regurgitation and in 2 pts severe tricuspid regurgitation was present. Patients were not operated during the acute phase of the disease. Five pts were reoperations and from those, all but one received mechanical prosthesis. RESULTS: In all operations the intention was to repair the mitral valve. In 46 pts complex mitral valvuloplasties were performed extended comissurotomies, shortening of chordae, chordal replacement with PTFE, and reconstruction of valve leaflefts by direct patching or pericardial extension of the retracted posterior leaflet (78.2% cases), plus reshaping of the annulus by using a fixed prosthetic CE ring (sizes 26 to 32) in every case. Ring sizes correlated poorly with body weights, but correlation was close and positive for the use of pericardial advancement of the posterior leaflet (p<0.01). There was no operative mortality, but one pt died early from sepsis and there was no late mortality. Maximum follow up extends now to 50 months (median 28 months) and functional evaluation, at latest follow up, as assessed by Doppler Echocardiography, showed residual mitral regurgitation, mild-moderate in 4 pts and LA-LV gradients mild in 5 and moderate in 2 pts. NYHA functional class, at present follow-up is class I for 43 pts (88%) and class II in the remaining 6 pts. Along the follow-up period 2 pts had to be reoperated for early repair failures and other three for late failures, presently freedom for reoperation is 91.8% at 5 years. CONCLUSIONS: Mitral valve repair in children with rheumatic lesions can be achieved for the great majority of cases by using different techniques. Pericardial extension of the retracted posterior leaflet allowed the use of a bigger size prosthetic ring. Intermediate functional results are good with fair functional classes and few reoperations but follow-up is short and does not allow us to draw conclusions about the long-term results of the repair in these rheumatic patients.

Orbital Exenteration for Eyelid Skin Carcinoma

Exenteration of the orbit is a disfiguring and destructive procedure; it is generally performed for orbital malignancies and often provides a significant reconstructive challenge. Our purpose was to evaluate the clinical indications for orbital exenteration in a tertiary referral center and to assess the reconstructive options employed. A retrospective nonrandomized analysis was performed, selecting all patients undergoing orbital exenteration over a 5-year period, between January 2005 and January 2010. Patient demographics, tumor characteristics, and reconstructive techniques used were evaluated. Twenty patients with a mean age of 76.5 years underwent total orbital exenteration. Basal cell carcinoma was the main operative indication (45%), followed by squamous cell carcinoma (15%). Reconstructive techniques included cover of the raw orbital cavity with a temporal muscular flap in all cases followed with split skin grafting (25%), bilaterally pedicle V-Y advancement flap (10%) and a fasciocutaneous island flap of the retroauricular region (65%). Twenty percent of patients had local complications and all were treated in a satisfactory fashion. Eyelid skin tumors remain an important cause of orbital exenteration. Temporal muscle flap is a reliable and stable reconstructive solution after orbital exenteration and additional aid is supplied with skin grafts or local flaps. This technique ensures a good aesthetic outcome and better situation for later complementary treatments and minimal associated donor site morbidity.

Access and information behaviour of European Documentation Centres users in Portugal and Spain: a comparative study

The aim of this study was to undertake a comparative analysis of the practices and information behaviour of European information users who visit information units specialising in European information in Portugal and Spain. The study used a quantitative methodology based on a questionnaire containing closed questions and one open question. The questions covered the general sociological profile of the respondents and their use of European Document Centres, in addition to analysing aspects associated with information behaviour relating to European themes. The study therefore examined data on the preferred means and sources for accessing European information, types of documents and the subjects investigated most. The use of European databases and the Internet to access material on Europe was also studied, together with the reasons which users considered made it easy or difficult to access European information, and the aspects they valued most in accessing this information. The questionnaire was administered in European Document Centres in 2008 and 2010.

Ulcerações Dolorosas do Couro Cabeludo

A arterite temporal é um vasculite sistémica que afecta vasos de médio e grande calibre, em particular a artéria temporal. Os autores apresentam o caso de um doente observado por ulcerações extensas e dolorosas da região parieto-temporal direita, com cefaleia hemicraniana homolateral, amaurose fugaz e claudicação mandibular. As artérias temporais eram espessadas, dolorosas e sem pulso à palpação. Analiticamente, registou-se anemia normocítica e normocrómica e velocidade de sedimentação de 63 mm na primeira hora. No exame histopatológico observou-se um processo inflamatório transmural, com células gigantes. O exame oftalmológico revelou compromisso da acuidade visual com maior expressão à direita. Perante o diagnóstico de arterite temporal, instituiu-se corticoterapia com prednisolona 1 mg/Kg/dia. A melhoria clínica foi significativa, embora com persistência das queixas oftalmológicas. Este caso reforça a importância do diagnóstico precoce desta patologia e da sua terapêutica atempada, minimizando a ocorrência de sequelas definitivas.

Temporomandibular Joint Ankylosis in an Infant: A Rare Cause of Difficult Airway

1.Pre-assessment data of the patient A 2-year-old boy, weighing 15 kg was admitted with a history of limited mouth opening(inter-incisor distance of 6 mm), hypoplastic and retrognathic mandible (bird face deformity) and facial asymmetry from left temporomandibular joint ankylosis (TMJA). He was born at term, after an uneventful pregnancy, and there was no report of trauma during caesarean section. No other possible aetiologies were identified. He was scheduled for mandibular osteotomy. Preoperative ENT examination revealed adenotonsillar hypertrophy. 2. Anaesthetic Plan A fiberoptic nasal intubation was performed under deep inhalation anaesthesia with sevoflurane, with the patient breathing spontaneously. Midazolam (0.05 mg.kg-1) and alfentanil (0.03 mg.kg-1) were given and anaesthesia was maintained with O2/air and sevoflurane. No neuromuscular blocking agent was administered since the surgical team needed facial nerve monitoring. 3. Description of incident During surgery an accidental extubation occurred and an attempt was made to reintubate the trachea by direct laryngoscopy. Although the osteotomy was nearly completed, the vocal cords could not be visualized (Cormack-Lehane grade IV laryngoscopic view). 4. Solving the problem Re-intubation was finally accomplished with the flexible fiberscope and the procedure was concluded without any more incidents. Extubation was performed 24 hours postoperatively with the patient fully awake. After surgery mouth opening improved to inter-incisor gap of 15 mm. 5. Lessons learned and take home message Two airways issues present in this case can lead to difficultventilation and intubation: TMJA and adenotonsillar hypertrophy. These difficulties were anticipated and managed accordingly. The accidental extubation brought to our attention the fact that, even after surgical correction, this airway remains challenging. Even with intensive jaw stretchingexercises there is a high incidence of re-ankylosis, especially in younger patients. One should bear that in mind when anaesthetizing patients with TMJA.

Blastic Plasmacytoid Dendritic Cell Neoplasm

Blastic plasmacytoid dendritic cell neoplasm is a rare and aggressive hematodermic neoplasia with frequent cutaneous involvement and leukemic dissemination. We report the case of a 76-year-old man with a 2 month history of violaceous nodules and a tumor with stony consistency, located on the head, and mandibular, cervical and supraclavicular lymphadenopathies. Multiple thoracic and abdominal adenopathies were identified on computerized tomography. Flow cytometry analysis of the skin, lymph node and bone marrow biopsies demonstrated the presence of plasmocytoid dendritic cell neoplastic precursor cells (CD4+, CD45+, CD56+ and CD123+ phenotype). After initial clinical and laboratorial complete remission with chemotherapy, the patient died due to relapse of the disease associated with the appearance of a cervical mass with medullary compromise.

Implementation of an IoT-based Sensor Network Integrating IoT-based Sensor Networks with Large-Scale Message Distribution

As technology advances not only do new standards and programming styles appear but also some of the previously established ones gain relevance. In a new Internet paradigm where interconnection between small devices is key to the development of new businesses and scientific advancement there is the need to find simple solutions that anyone can implement in order to allow ideas to become more than that, ideas. Open-source software is still alive and well, especially in the area of the Internet of Things. This opens windows for many low capital entrepreneurs to experiment with their ideas and actually develop prototypes, which can help identify problems with a project or shine light on possible new features and interactions. As programming becomes more and more popular between people of fields not related to software there is the need for guidance in developing something other than basic algorithms, which is where this thesis comes in: A comprehensive document explaining the challenges and available choices of developing a sensor data and message delivery system, which scales well and implements the delivery of critical messages. Modularity and extensibility were also given much importance, making this an affordable tool for anyone that wants to build a sensor network of the kind.