996 resultados para Lea, Langdon "Biff"


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Pós-graduação em Ciência e Tecnologia Animal - FEIS

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Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

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The Lewis histo-blood group system is characterized by the expression of the Lea and Le(b) antigens in the gastrointestinal tract, whose synthesis results in interactions between alpha 2-L-fucosyltransferase (FUTII) and alpha 3/4-L-fucosyltransferase (FUTIII) enzymes coded by the FUT2 (19q. 13.3) and FUT3 (19p13.3) genes. FUTII and FUTIII fucosylate the type 1 oligosaccharide precursor (Gal beta 1 -> 3NAcGlc beta 1 -> 3-R) at distinct positions to form H type 1 (Fuc alpha 1. 2Gal beta 1. 3NAcGlc beta 1 -> 3-R) and Le(a) (Gal beta 1 -> 3[Fuc alpha 1 -> 4] NAcGlc beta 1 -> 3-R) antigens, respectively. The fucosylation of H type 1 antigens by FUTIII results in the Leb antigen (Fuc alpha 1. 2Gal beta 1. 3[Fuca1. 4] NAcGlc beta 1. 3-R). Thus, the presence of the FUTII and FUTIII enzymes leads to the expression of the Le(a+b+) phenotype, while the presence of only FUTIII allows the expression of the Le(a+b-) phenotype. The absence of the FUTIII enzyme leads to the expression of the Le(a-b-) phenotype, independent of the presence or absence of FUTII. Point mutations in FUT2 and FUT3 genes change the activity of these enzymes, impair the synthesis of Le(a) and Le(b) antigens, and contribute to the variability of Lewis phenotypes in the gastrointestinal tract. Toxoplasma gondii, an apicomplexan parasite that infects a large proportion of the world's population, utilizes the gastrointestinal tract as an infection route and seems to adhere to glycosylated molecules to invade human cells. These apparently independent events may be related. The aim of this study was to test the hypothesis that there is an association between the Lewis histo-blood group system and infection by T. gondii. Two hundred and nine serum samples collected from pregnant women were submitted to screening tests to detect anti-T. gondii antibodies, employing the indirect hemagglutination method. ELISA was utilized to identify IgG class anti-T. gondii antibodies specific for the RH strain. A hundred and ninety-five samples with concordant results for both methods were selected to form two groups: seropositive (G1) and seronegative (G2). The G428A mutation of the FUT2 gene, and T202C and C314T of the FUT3 gene, which allow inference of the gastrointestinal tract Lewis phenotypes, were identified using PCR-RFLP and PCR-SSP methods, respectively. Among the 195 samples selected, 116 (59.5%) were seropositive and 79 (40.5%) were seronegative. In G1, 68 (58.6%) were classified as Le(a+b+), 30 (25.9%) as Le(a+b-), and 18 (15.5%) as Le(a-b-), and in G2, 67 (84.8%) were classified as Le(a+b+), 12 (15.2%) as Le(a+b-), and 0 (0%) as Le(a-b-) (P < 0.0001). The Le(a-b-) phenotype is associated with a high risk of RH strain T. gondii infection when compared with the Le(a+b+) [P = 0.0001; OR = 36,460; 95%CI = 2.152-617,680] and Le(a+b-) phenotypes [P = 0.0118; OR = 15,165; 95%CI = 0.8463-271,710]. The Le(a+b-) phenotype showed a higher risk compared to the Le(a+b+) phenotype [P = 0.0206; OR = 2463; 95%CI = 2463-5214]. The results suggest that the Le(a-b-) phenotype is strongly associated with a greater risk of infection by the RH strain of T. gondii compared to the other phenotypes. It is possible that the absence of fucosylation of the type 1 oligosaccharide precursor as well as the variations in the structures of the Le(a) and Le(b) antigens influence susceptibility to infection by this parasite.

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The professional market for physical education and fitness demands for perfect and aesthetically beautiful bodies from its professionals, and the additional pressure of media, both add to the risk for body image dissatisfaction among these professional, increasing the risk for developing body image distortions and, ultimately, eating disorders. Body image dissatisfaction affects more women in their attempts for thin ideal. However, lately, because of social pressure for body aesthetical habits in both genders, men are faced with higher risk for distortions in body perception, leading to unhealthy eating habits and pathogenic exercise. With this in mind, the purpose of this study was to compare freshmen and senior physical education (PE) students from the State University of São Paulo (UNESP), as well as to make gender comparisons. Two groups comprise each, 46 freshmen PE students (23 females and 23 males), average age 18.7 ± 1.7 years; and 26 senior PE students (13 females and 13 males), average age 23 ± 1.9 years. Both groups filled out the questionnaires: Eating Attitudes Test/ EAT-26, Body Shape Questionnaire/ BSQ, Body Shape Questionnaire/ BSQ, and motivation state questionnaire/ LEA-RI. Results showed that the majority of participants wanted to change some aspect of their looks; women were more dissatisfied with their bodies than men; eating behavior scores were within the normal range for both groups. Finally, freshmen PE students are at a higher risk for body image distortion than senior PE students. We concluded that women, as well as younger individuals in general, are at higher risk for body image distortions. It is likely that experience in the further years of a physical education course has positive impact on body self image.

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O ambiente virtual está cada vez mais presente na vida do ser humano e, por este motivo, não se pode negligenciar a perspectiva de que os jogos eletrônicos possam ser encampados no contexto das aulas de Educação Física, com as devidas adaptações, proporcionando novas práticas, as quais sejam atraentes, no sentido de ampliar as perspectivas de adesão ao movimento e minimizar as condições do sedentarismo. Desta forma, este trabalho, de natureza qualitativa, teve como objetivo propor a adaptação de alguns jogos eletrônicos, os quais puderam ser aplicados corporalmente, como novas possibilidades de atividades a serem vivenciadas em aulas de Educação Física, bem como, investigar os níveis de estado de ânimo e de satisfação dos alunos frente às aulas que utilizaram esses jogos eletrônicos adaptados. O estudo foi desenvolvido por intermédio da união de pesquisas bibliográfica e exploratória. Para tanto, fizeram parte deste estudo uma amostra intencional, composta por 60 alunos, de ambos os sexos, compreendendo a faixa etária de 10 a 15 anos, pertencentes a uma escola da rede oficial de ensino da cidade de Rio Claro/SP, selecionada por conveniência, a qual participou de uma aula, ministrada pela pesquisadora, composta por três jogos eletrônicos adaptados. Para se verificar o estado de ânimo dos alunos, foi aplicada a Lista de Estados de Ânimo Reduzida e Ilustrada (LEA-RI), desenvolvida por Volp (2000), antes e após as aulas. Foi aplicado, ainda, um questionário contendo perguntas abertas, com o intuito de se verificar o nível de satisfação dos alunos em relação aos jogos eletrônicos adaptados. Os dados foram analisados por meio da Técnica de Análise de Conteúdo Temático. Os resultados apontaram que os jogos eletrônicos, vinculados à aula de Educação Física, influenciam positivamente na motivação dos alunos... (Resumo completo, clicar acesso eletrônico abaixo)

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Atualmente pode-se observar a importância da atividade física na vida diária da população promovendo, além dos benefícios físicos, benefícios sociais e psicológicos. Nesse sentido a atividade física, mais especificamente a ginástica sistematizada (Body Systems), hoje em dia adepta a boa parcela da população, se tornou importante para seus praticantes, visando à prevenção de lesões, normalizando as funções corporais e proporcionando descontração e socialização. O objetivo geral deste trabalho foi analisar a interferência das aulas de ginástica sistematizadas nos estados de ânimo de seus participantes. Participaram do estudo 35 indivíduos, de ambos os gêneros, estudantes do curso de Educação Física da UNESP de Rio Claro, SP, com disponibilidade para executar as intervenções semanais e que pudessem responder as listas de estados de animo (LEA-RI) antes e após a aula. Neste estudo foram analisados três estilos diferentes de ginástica, a ginástica com pesos, BODYPUMP, a ginástica cardiorrespiratória, BODYATTACK e a ginástica de condicionamento postural que provém de técnicas como o Yoga e o Pilates, o BODYBALANCE. Com base na analise binomial foi possível chegar a alguns resultados significativos quanto à interferência das aulas de ginástica nos estados de animo de seus praticantes. Ao praticar a aula de BODYBALANCE as pessoas se sentiram mais felizes, mais leves e menos desagradáveis correspondendo a proposta da aula. Com o BODYPUMP as pessoas se sentiram mais pesadas e na aula de BODYATTACK sentiram-se além de mais pesadas, menos tímidas, ou melhor, mais descontraídas. Isso mostra que as aulas de ginastica podem ser utilizadas não apenas para benefícios físicos, mas também com objetivos de direcionar para a alteração de determinados aspectos psicológicos

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Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

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Pós-graduação em Ciências da Motricidade - IBRC

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Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

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Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

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The aim of this study was to use proximate chemical composition, macro and trace elements, fatty acid profile and stable isotopes as traceability tools to assess geographic origin and seasonality of croaker (Micropogonicts fumieri). Croaker from Parnaiba contained higher ash in July and lower fat content than croaker from Santos. In contrast, croaker from Santos had statistically higher proportion of 16:1n-9+16:1n-7, 20:1n-11, 20:1n-9, MUFA and n-3/n-6 ratio than croaker from Parnaiba. Concerning seasonality, croaker caught in July had significantly higher amounts of 14:0, 15:0, 16:1n-9+16:1n-7 and saturated fatty acids than fish caught in December. Concerning elements, significant differences were also detected between seasons for Cl, Ca, Fe, Sr and S, whereas differences between geographic origins were only observed with K. delta C-13 and delta N-15 were statistically different between geographic origins, whereas differences between seasons were only detected in delta N-15 ratio of croaker from Santos. Fatty acids, minerals and stable isotope are effective methods to trace geographic origin and seasonality of croaker. Nonetheless, further investigation is still required with larger samples of croaker to enable the implementation of fatty acids, elements or stable isotope as authenticity tools by food control agencies. (C) 2014 Elsevier Ltd. All rights reserved.

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Pós-graduação em Desenvolvimento Humano e Tecnologias - IBRC

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Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

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Introduction: Sedentary behavior is characterized by individuals who designed much of the day sitting or lying down activities, even if such conduct regular physical activity. Over the years people tend to be less active, worsening the quality of life. For healthy aging is necessary for the individual to be constantly active, and moving activities improve mood and quality of life, though little is known of the influence of sedentary behavior in these variables. Aim: To investigate the association between sedentary time, quality of life and mood states of elderly women engaged in physical activity. Methodology: The study included 68 elderly women who belong to the Physical Activity Program for the Elderly (PROFIT), for at least 6 months. These answered the Sedentary Behaviour Questionnaire, the Pentacle Welfare and IPAQ Short Version. The Pep States List Reduced and Illustrated (LEA-RI) was applied before and after a workout and before and after three times of sedentary behaviors. To evaluate the difference of sedentary behavior time average for each domain of quality of life was conducted the analysis of the 95% confidence interval for the STATA program version 12.0 and to the moods list data a non-parametric test - test binomial using SPSS version 17.0 program and has adopted a p≤0,05. Results: A moderate intensity physical activity was the most practiced (939.5 ± 650.2 min / week) and the activity most frequently performed in sedentary time was watching television (187.6 ± 96,4min / day). In general, the quality of life for the elderly is considered good (98.39%) and the disease is most prevalent hypertension (29.47%). After a physical activity older felt less useless, less shy and less fear and after a sedentary behavior, felt less agitated and less useless. In relation between the domains of QOL and sedentary behavior time, there were no statistical differences. Conclusion: Elderly active even after a sedentary behavior...