994 resultados para Hertwig, Oscar,
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1905 (A18).
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1895 (A8).
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1893 (A6).
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1890 (A3).
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OBJETIVO: Apresentar um software que permita uma análise detalhada da dinâmica da deglutição. MATERIAIS E MÉTODOS: Participaram deste estudo dez indivíduos após acidente vascular encefálico, sendo seis do gênero masculino, com idade média de 57,6 anos. Foi realizada videofluoroscopia da deglutição e as imagens foram digitalizadas em microcomputador, com posterior análise do tempo do trânsito faríngeo da deglutição, por meio de um cronômetro e do software. RESULTADOS: O tempo médio do trânsito faríngeo da deglutição apresentou-se diferente quando comparados os métodos utilizados (cronômetro e software). CONCLUSÃO: Este software é um instrumento de análise dos parâmetros tempo e velocidade da deglutição, propiciando melhor compreensão da dinâmica da deglutição, com reflexos tanto na abordagem clínica dos pacientes com disfagia como para fins de pesquisa científica.
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The fusion of bone marrow (BM) hematopoietic cells with hepatocytes to generate BM derived hepatocytes (BMDH) is a natural process, which is enhanced in damaged tissues. However, the reprogramming needed to generate BMDH and the identity of the resultant cells is essentially unknown. In a mouse model of chronic liver damage, here we identify a modification in the chromatin structure of the hematopoietic nucleus during BMDH formation, accompanied by the loss of the key hematopoietic transcription factor PU.1/Sfpi1 (SFFV proviral integration 1) and gain of the key hepatic transcriptional regulator HNF-1A homeobox A (HNF-1A/Hnf1a). Through genome-wide expression analysis of laser captured BMDH, a differential gene expression pattern was detected and the chromatin changes observed were confirmed at the level of chromatin regulator genes. Similarly, Tranforming Growth Factor-β1 (TGF-β1) and neurotransmitter (e.g. Prostaglandin E Receptor 4 [Ptger4]) pathway genes were over-expressed. In summary, in vivo BMDH generation is a process in which the hematopoietic cell nucleus changes its identity and acquires hepatic features. These BMDHs have their own cell identity characterized by an expression pattern different from hematopoietic cells or hepatocytes. The role of these BMDHs in the liver requires further investigation.
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Objective: The purpose of this study was to identify the influence of readiness of change for physical activity (PA), sociodemographic factors, lifestyle and physical activity status (PAS) on perceived barriers among Spanish university students. Participants: Seven hundred and seventy two (n = 772) men and women ages 17 - 39 at a north-west regional university in Spain participated in the study. Methods: The International Physical Activity Questionnaire, the States of Change for Physical Activity Behaviour Questionnaire and the Self-perceived Barriers for Physical Activity Questionnaire were used. Description, correlation and multiple regression analyses were completed. Results: Participants self-perceived low average-score barriers (2.6 ± 1.4 over 10.0). The 3-higher scores barriers corresponded to “too much work”; “lack of time for exercise” and “laziness”. Gender, PAS and self-perceived health were shown to be associated with perceived barriers. Conclusions: University institutions should consider those factors that predict barriers to PA to develop effective intervention programs.
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Aquest projecte està encarat a avaluar un protocol de prevenció de luxacions i subluxacions d’espatlla en el judo. L’objectiu principal és el de reduir el nombre de luxacions i subluxacions d’espatlla en judokes de categories compreses entre les categories cadet i absoluta millorant paràmetres com la força, la elasticitat muscular, la propiocepció, l’alimentació i la condició física dels esportistes. Aquest serà un estudi experimental amb dos grups, on el Centre de Tecnificació del Bages un realitzarà el protocol objecte d’estudi i el grup de la Federació Catalana de Judo i D.A seguiran amb la seva activitat habitual. Cada grup estarà format per 37 esportistes amb un risc alfa de 0.05 i un risc beta inferior al 0.2, amb una taxa de pèrdua de seguiment d’un 10%. Aquest protocol de prevenció pot ser útil en la nostre comunitat, però no té perquè ser-ho en altres països o regions depenent del tipus de judo que es realitza a cada lloc. Abans de començar amb l’actuació del protocol es realitzaran avaluacions biomecàniques per conèixer l’estat dels esportistes i poder actuar analíticament on més ho necessiti cada integrant de l’estudi.
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Connectivity analysis on diffusion MRI data of the whole- brain suffers from distortions caused by the standard echo- planar imaging acquisition strategies. These images show characteristic geometrical deformations and signal destruction that are an important drawback limiting the success of tractography algorithms. Several retrospective correction techniques are readily available. In this work, we use a digital phantom designed for the evaluation of connectivity pipelines. We subject the phantom to a âeurooetheoretically correctâeuro and plausible deformation that resembles the artifact under investigation. We correct data back, with three standard methodologies (namely fieldmap-based, reversed encoding-based, and registration- based). Finally, we rank the methods based on their geometrical accuracy, the dropout compensation, and their impact on the resulting connectivity matrices.
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L"article presenta el plantejament i desenvolupament d"una recerca acció per al desenvolupament de la competència transversal «capacitat crítica i autocrítica» de la Universitat de Barcelona (UB). El projecte s"ha desenvolupat dins de diverses assignatures d"alguns ensenyaments de la UB (Ciència i Tecnologia dels Aliments, Infermeria, Odontologia, Pedagogia i Química) i l"hem iniciat sis professors i professores novells amb l"objectiu de dissenyar i desenvolupar activitats i estratègies de treball per promoure el pensament crític i autocrític dels estudiants universitaris. Aquest projecte s"ha portat a terme mitjançant un procés de recerca acció que es va iniciar en les primeres etapes amb una reflexió sobre la nostra pròpia pràctica docent. A partir d"aquesta reflexió es van dissenyar una sèrie d"activitats per promoure aquesta competència transversal. En aquest treball es descriuen el desenvolupament d"aquest projecte i els resultats obtinguts en aplicar algunes de les activitats a diverses assignatures dels ensenyaments mencionats. Les activitats han permès que l"alumnat pugui desenvolupar el pensament crític i autocrític en treballar sobre diversos aspectes de les assignatures (competències específiques, activitats, proves d"avaluació, etc.), i que alhora pugui ser crític amb el seu procés d"aprenentatge. Això també ha permès desenvolupar un dels reptes de l"espai europeu d"educació superior (EEES), en què es pretén donar a l"estudiant un rol més important en el procés d"aprenentatge.
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We investigate what processes may underlie heterogeneity in social preferences. We address this question by examining participants' decisions and associated response times across 12 mini-ultimatum games. Using a finite mixture model and cross-validating its classification with a response time analysis, we identified four groups of responders: one group takes little to no account of the proposed split or the foregone allocation and swiftly accepts any positive offer; two groups process primarily the objective properties of the allocations (fairness and kindness) and need more time the more properties need to be examined; and a fourth group, which takes more time than the others, appears to take into account what they would have proposed had they been put in the role of the proposer. We discuss implications of this joint decision-response time analysis.
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As fístulas arteriovenosas da região do seio cavernoso são lesões raras e difíceis de diagnosticar. Elas são classificadas em fístulas durais do seio cavernoso e fístulas carótido-cavernosas diretas. Apesar de apresentarem sintomas semelhantes, o diagnóstico preciso é importante, já que o tratamento é específico para cada uma delas. As alterações encontradas nos exames de imagem são muito semelhantes, tanto nas fístulas durais do seio cavernoso quanto nas fístulas carótido-cavernosas, contudo, é possível diferenciá-las. Dentre os exames de imagem disponíveis (ultrassonografia de órbita com Doppler, tomografia computadorizada, ressonância magnética e angiografia com subtração digital), a angiografia é considerada padrão ouro para o diagnóstico e classificação das fístulas arteriovenosas da região do seio cavernoso. O objetivo deste ensaio é mostrar de modo didático a classificação e o aspecto por imagem das fístulas arteriovenosas do seio cavernoso.
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Simple Heuristics in a Social World invites readers to discover the simple heuristics that people use to navigate the complexities and surprises of environments populated with others. The social world is a terrain where humans and other animals compete with conspecifics for myriad resources, including food, mates, and status, and where rivals grant the decision maker little time for deep thought, protracted information search, or complex calculations. Yet, the social world also encompasses domains where social animals such as humans can learn from one another and can forge alliances with one another to boost their chances of success. According to the book's thesis, the undeniable complexity of the social world does not dictate cognitive complexity as many scholars of rationality argue. Rather, it entails circumstances that render optimization impossible or computationally arduous: intractability, the existence of incommensurable considerations, and competing goals. With optimization beyond reach, less can be more. That is, heuristics--simple strategies for making decisions when time is pressing and careful deliberation an unaffordable luxury--become indispensible mental tools. As accurate as or even more accurate than complex methods when used in the appropriate social environments, these heuristics are good descriptive models of how people make many decisions and inferences, but their impressive performance also poses a normative challenge for optimization models. In short, the Homo socialis may prove to be a Homo heuristicus whose intelligence reflects ecological rather than logical rationality.
Construção de equipamentos de refrigeração que permitem trabalhar com temperaturas de -40ºC ou -60ºC
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In this article we describe the construction of two cooling systems with an immersion probe which will allow one to work at temperatures of either -40ºC or -60ºC. The two systems were constructed with readily available components and have been used daily for the last year in our laboratory to carry out reactions at low temperature or to cool down traps of vacuum pumps, reducing our need of dry-ice or liquid nitrogen.