Etelä-Pohjanmaan ELY-keskuksen alueen pohjavesien toimenpideohjelma 2016-2021

Vesienhoidon keskeisenä tavoitteena on estää jokien, järvien ja rannikkovesien sekä pohjavesien tilan heikkeneminen sekä pyrkiä kaikkien vesien vähintään hyvään tilaan. Erinomaisiksi tai hyviksi arvioitujen vesien tilaa ei saa heikentää. Tavoitteen saavuttamiseksi suunnitellaan ja toteutetaan vesien tilaa parantavia toimenpiteitä ja seurataan niiden vaikutuksia. Vesienhoidossa otetaan huomioon myös merenhoidon, tulvariskien hallinnan sekä luonnonsuojelun tavoitteet. Vesienhoitoa suunnitellaan vesienhoitoalueittain, joita on Manner-Suomessa seitsemän. Vesienhoitoalue muodostuu yhdestä tai useammasta vesistöalueesta. Etelä-Pohjanmaan ELY-keskuksen ympäristövastuu-alueen alue kuuluu Kokemäenjoen-Saaristomeren-Selkämeren vesienhoitoalueeseen. Vesienhoidon suunnittelu etenee kuuden vuoden jaksoissa. Ensimmäiset vuoteen 2015 ulottuvat toimenpideohjelmat laadittiin laajassa yhteistyössä 2008-2009. Lisätietoa vesienhoidosta ja vesienhoidon järjestämisestä vesienhoitoalueella on saatavilla osoitteessa www.ymparisto.fi/lantinenvesienhoitoalue.

Eighty years 'Owre the Sea': Robert Burns and the early United States of America, c. 1786-1866.

This thesis represents the first extensive critical study of the relationship between Robert Burns and the early United States of America. Spanning literature, history and memory studies, the following chapters take an interdisciplinary approach towards investigating the methods by which Burns and his works rose to prominence and came to be of cultural and literary significance in America. Theoretically, these converging disciplines intersect through a transnational, Atlantic Studies perspective that shifts emphasis from Burns as the 'national poet of Scotland' onto the various socio-cultural connections that facilitated the spread of his work and reputation. In addition to Scottish literary studies, the thesis contributes to the broader fields of Transatlantic, Transnational and American Studies. Previous studies have suggested that Burns's popularity in the early United States might be attributed to his kinship with 'national' American ideals of freedom, egalitarianism and individual liberty. While some of the evidence supports this claim, this thesis argues that it also wrongly assumes a spatiotemporal unity for the nineteenth-century American nation. It concludes by suggesting that future critical studies of the poet must heed the multifarious complexities of 'national' paradigms, pointing the way to further work on the reception and influence of Burns in other 'global' or, indeed, transnational contexts.

Civil War, 1861-1862 /

Shows movement of Union and Confederate forces, location of their respective victories, extent of their respective territories controlled in Dec. 1862, and the Union naval blockade.

Architectural gems from Ely Cathedral : and the monastic buildings.

Illustrations engraved by W. Woolnoth, S. Rawle, F.J. Havell, and E. Challis.

El segundo comentario de Abraham Ibn Ezra al libro del Cantar de los Cantares. Edición crítica, traducción, notas y estudio introductorio

We herewith present the critical edition, translation and notes from the second commentary of Abraham ibn Ezra on the Song of Songs. This work is preceded by an introductory study that considers among others, various aspects of the commentary and the influence that the previous and contemporary Jewish exegesis to Ibn Ezra’s may exert on his interpretations of the Song of Songs. Finally, we analyze some of the features that are part of the commentary of Ibn Ezra on the Canticles. Summary: Objectives and results It is the purpose of this work to go into detail about the study of the exegetical texts of Abraham ibn Ezra, and in particular the text of this second commentary of Ibn Ezra on Song of Songs, whose translation and critical edition is the subject of this work. This is especially interesting since it is one of the few translations from the original Hebrew, among which are the Latin translation of Gilberto Genebrardo, published in Paris in 1585 and the English edition of Richard A. Block, published in 1982 in Cincinnati. This edition of the second commentary of Ibn Ezra on the Song of Songs continues the lead of previous work carried out in the translation and critical edition of Ibn Ezra's comments to Ecclesiastes, Esther, and Job by Mariano Gómez Aranda and the commentary to Book of Ruth by Maria Josefa Azcárraga Servert. The translation of Abraham ibn Ezrás text on the aforementioned second commentary on the Song of Songs, and the drawing up of the critical edition by selecting manuscripts that, once collated, will lead to the Hebrew text that will be used for the Castilian version is the basis of the present work. Of the thirty-three existing manuscripts of Ibn Ezra's commentary on the Canticles, ten have been rejected in principle since they belong to the first commentary, whose text on two manuscripts was translated into English by H. J. Mathews in 1874. Only thirteen out of the remaining twenty three manuscripts have been used for drawing up the critical edition, since ten of them have not been included in the present edition in spite of their belonging to the second commentary...

Análisis del discurso político: estrategia hegemónica rusa para la conquista de territorio durante 1861 -1928 y 1991

La presente investigación pretende explorar la relación entre el discurso político y un proyecto hegemónico ruso para la conquista de territorio en la península de Crimea mediante la migración humana, evidente en los hechos de 2014. A partir de la evaluación de algunos momentos de migración en los últimos dos siglos (1860, 1928 y 1991) se vincula la práctica articulatoria del discurso político de cada una de las elites políticas rusas de turno con la crisis política en Crimea 2014. Lo anterior permite identificar un cierto proyecto hegemónico ruso –transversal en el tiempo - que tuvo como resultado principal la anexión de facto de Crimea a Rusia. Ésta no habría sido posible sin las acciones políticas de cada una de los gobernantes que motivaron la migración hacia Crimea, lo cual puede ser en gran parte uno de los motivos para la gran concentración de rusos en Crimea que votaron a favor de unirse a Rusia y dejar a Ucrania.

Aviso sobre los “avisos”. Los anuncios periódicos como fuente histórica (1857-1861)

IntroducciónLa utilización de los periódicos como fuente, por parte de los historiadores de Costa Rica, se limita casi siempre a los textos de contenido (cartas, noticias, reportajes, editoriales, comunicados, etc.) estratégicos para el estudio de distintos sectores y conflictos sociales, El propósito de esta selección de documentos es, sin embargo, destacar la riqueza que brinda, enj especial a partir de 1850, otro tipo de materiales: los "avisos" -publicitarios o no-, útiles para explorar con detalle diversos aspectos de la vida económica y cultural del país, particularmente en al esfea del quehacer cotidiano...

Efeito da temperatura noturna sobre desenvolvimento de Chrysoperla externa (Hagen, 1861) (Neuroptera: Chrysopidae).

2016

Planejamento da atenção aos hipertensos da Equipe Saúde da Família Dr. Ely de Araújo Barbosa em Bela Vista/MS

Tendo por objetivo principal a melhora dos níveis de controle da hipertensão arterial nos pacientes assistidos no ESF Dr. Ely de Araújo Barbosa em Bela Vista/MS, este trabalho consiste em um projeto de intervenção, através de ações simples e eficazes, modificando os nós críticos presentes. Conseguimos tal efeito com ações como mobilizar a população alvo para prática de atividade física regular e conscientização do hipertenso de sua real situação, que foram aplicados através de prática conjunta de exercícios, reuniões esclarecedoras mensais, aumento do número de consultas para hipertensos. Os resultados colhidos mostraram que, apesar do pouco tempo de aplicação, conseguiu-se colher frutos positivos, inclusive com redução do risco cardiovascular de alguns pacientes.

An Asp49 Phospholipase A2 From Snake Venom Induces Cyclooxygenase-2 Expression And Prostaglandin E2 Production Via Activation Of Nf-κb, P38mapk, And Pkc In Macrophages.

Phospholipases A2 (PLA2) are key enzymes for production of lipid mediators. We previously demonstrated that a snake venom sPLA2 named MT-III leads to prostaglandin (PG)E2 biosynthesis in macrophages by inducing the expression of cyclooxygenase-2 (COX-2). Herein, we explored the molecular mechanisms and signaling pathways leading to these MT-III-induced effects. Results demonstrated that MT-III induced activation of the transcription factor NF-κB in isolated macrophages. By using NF-κB selective inhibitors, the involvement of this factor in MT-III-induced COX-2 expression and PGE2 production was demonstrated. Moreover, MT-III-induced COX-2 protein expression and PGE2 release were attenuated by pretreatment of macrophages with SB202190, and Ly294002, and H-7-dihydro compounds, indicating the involvement of p38MAPK, PI3K, and PKC pathways, respectively. Consistent with this, MT-III triggered early phosphorylation of p38MAPK, PI3K, and PKC. Furthermore, SB202190, H-7-dihydro, but not Ly294002 treatment, abrogated activation of NF-κB induced by MT-III. Altogether, these results show for the first time that the induction of COX-2 protein expression and PGE2 release, which occur via NF-κB activation induced by the sPLA2-MT-III in macrophages, are modulated by p38MAPK and PKC, but not by PI3K signaling proteins.

Identification Of Target Genes Using Gene Expression Profile Of Granulocytes From Patients With Chronic Myeloid Leukemia Treated With Tyrosine Kinase Inhibitors.

Differential gene expression analysis by suppression subtractive hybridization with correlation to the metabolic pathways involved in chronic myeloid leukemia (CML) may provide a new insight into the pathogenesis of CML. Among the overexpressed genes found in CML at diagnosis are SEPT5, RUNX1, MIER1, KPNA6 and FLT3, while PAN3, TOB1 and ITCH were decreased when compared to healthy volunteers. Some genes were identified and involved in CML for the first time, including TOB1, which showed a low expression in patients with CML during tyrosine kinase inhibitor treatment with no complete cytogenetic response. In agreement, reduced expression of TOB1 was also observed in resistant patients with CML compared to responsive patients. This might be related to the deregulation of apoptosis and the signaling pathway leading to resistance. Most of the identified genes were related to the regulation of nuclear factor κB (NF-κB), AKT, interferon and interleukin-4 (IL-4) in healthy cells. The results of this study combined with literature data show specific gene pathways that might be explored as markers to assess the evolution and prognosis of CML as well as identify new therapeutic targets.

Treadmill Training Increases Sirt-1 And Pgc-1 α Protein Levels And Ampk Phosphorylation In Quadriceps Of Middle-aged Rats In An Intensity-dependent Manner.

The present study investigated the effects of running at 0.8 or 1.2 km/h on inflammatory proteins (i.e., protein levels of TNF- α , IL-1 β , and NF- κ B) and metabolic proteins (i.e., protein levels of SIRT-1 and PGC-1 α , and AMPK phosphorylation) in quadriceps of rats. Male Wistar rats at 3 (young) and 18 months (middle-aged rats) of age were divided into nonexercised (NE) and exercised at 0.8 or 1.2 km/h. The rats were trained on treadmill, 50 min per day, 5 days per week, during 8 weeks. Forty-eight hours after the last training session, muscles were removed, homogenized, and analyzed using biochemical and western blot techniques. Our results showed that: (a) running at 0.8 km/h decreased the inflammatory proteins and increased the metabolic proteins compared with NE rats; (b) these responses were lower for the inflammatory proteins and higher for the metabolic proteins in young rats compared with middle-aged rats; (c) running at 1.2 km/h decreased the inflammatory proteins and increased the metabolic proteins compared with 0.8 km/h; (d) these responses were similar between young and middle-aged rats when trained at 1.2 km. In summary, the age-related increases in inflammatory proteins, and the age-related declines in metabolic proteins can be reversed and largely improved by treadmill training.