984 resultados para EPIDERMAL-KERATINOCYTES


Relevância:

10.00% 10.00%

Publicador:

Resumo:

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

Relevância:

10.00% 10.00%

Publicador:

Resumo:

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Relevância:

10.00% 10.00%

Publicador:

Resumo:

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

Relevância:

10.00% 10.00%

Publicador:

Resumo:

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

Relevância:

10.00% 10.00%

Publicador:

Resumo:

Squamous cell carcinoma is a keratinocytes malignant tumor, the definitive diagnosis of this disease is based on histopathology examination of the lesions. The cats nostrils is one of regions commonly affected by this neoplasm. The response to chemotherapeutic agents, cryosurgery and radiotherapy is poor and for this reason surgical resection is instituted for remove the greatest amount of tissue engaged and provide free margins, in case of nasal involvement are indicated nosectomy often needing reconstructive techniques using as advance flaps for synthesis of surgical wounds. Due to the high incidence of feline patients with this entity, this study aims to report and discuss the effectiveness of nosectomy in seven cats with the disease. It is concluded that nosectomy as a therapeutic technique effective in five of seven cats, resecting tumor margin and providing acceptable time and quality life.

Relevância:

10.00% 10.00%

Publicador:

Resumo:

A better understanding of the paracrine and autocrine regulatory loops within the cumulus-oocyte complex (COC) is fundamental for the improvement of in vitro maturation (IVM) outcomes in humans and domestic species. This review presents the most important local regulators identified in the COC to date with special attention to those secreted by the oocyte and acting on cumulus cells, as well as their roles in different processes crucial for the successful maturation of the COC. An autocrine regulatory loop mediated by epidermal growth factor-like (EGF-like) peptides in cumulus cells triggers COC maturation. During COC differentiation, oocyte secreted factors (OSFs), particularly members of the transforming growth factor-beta (TGF beta) and fibroblast growth factor (FGF) families, regulate meiotic resumption, cumulus expansion, cumulus metabolism, apoptosis and steroidogenesis.

Relevância:

10.00% 10.00%

Publicador:

Resumo:

Bulbophyllum, which comprises 1876 species, is considered the second largest genus of angiosperms, with a pantropical distribution. The morphological and anatomical floral studies in the genus are incipient, with data restricted to the gynostemium and lip of some species. Based on molecular data, six sections were recognized within Bulbophyllum at the Neotropics, amongst them Bulbophyllum sect. Micranthae, which comprises 12 species distributed in central South America. We aimed to study the floral anatomy of six species of Bulbophyllum sect. Micranthae, in order to determine useful characters to differentiate them and contribute to the anatomical characterization of the section as a whole. Floral anatomy was assessed through usual techniques of light microscopy. The data found here for B. adiamantinum, B. chloroglossum, B. epiphytum, B. mentosum, B. micranthum and B. rupicolum allowed to identificate the presence of glandular trichomes and the possible presence of a secretory region on the lip, which might produce substances used as a reward to pollinators. The most significant anatomical characters to the species characterization were the shape and ornamentation of the outer periclinal walls of the epidermal cells, as well as the number of vascular bundles in dorsal and lateral sepals and at the lip. The data also allowed the differentiation between B. epiphytum and B. rupicolum, species very similar in morphology and phylogenetically related. Besides that, the data also allowed the discussion regarding the maintenance of B. mentosum within the section: although its inclusion is supported by molecular studies, the anatomical data here presented shows greater differences compared to the other species, not supporting its maintenance in Bulbophyllum sect. Micranthae

Relevância:

10.00% 10.00%

Publicador:

Resumo:

Pemphigus complex in animals is considered rare, but not so when compared with the occurrence of other autoimmune diseases. Pemphigus Foliaceus in dogs is the most common varieties of pemphigus and is characterized clinically by intraepidermal pustules, starting on the face and ears, pads, groin, and may become multifocal or generalized in six months. As the pustules are very fragile, the lesions usually found are secondary, which may range from dry to collarettes epidermal crusting, and nasal depigmentation. The diagnosis is difficult because presents sintomatology similar to other diseases and laboratory diagnosis more precise through the histopathological examination of pustules integrate (biopsy), which are rarely found. The treatment, although of the individual treatment regimen, is based on treating opportunistic diseases and immunosuppressing the animal in order to decrease the production of autoantibodies. The drugs of choice depend on the clinical presentation, however is usually oral prednisone and azathioprine in the dog and combined immunosuppressive therapy. Should make use daily until the disease is inactive and gradually decrease the dose until have the minimum effective dose, preferably on alternate days for the remission of the disease. Prognosis of pemphigus varies according to disease stage and treatment established. Pemphigus foliaceus is less serious nonetheless might be fatal without treatment

Relevância:

10.00% 10.00%

Publicador:

Resumo:

Pós-graduação em Medicina Veterinária - FCAV

Relevância:

10.00% 10.00%

Publicador:

Resumo:

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Relevância:

10.00% 10.00%

Publicador:

Resumo:

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Relevância:

10.00% 10.00%

Publicador:

Resumo:

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)