Mannose-binding lectin and MBL-associated serine protease-2 gene polymorphisms in a Brazilian population from Rio de Janeiro

Mannose-binding lectin (MBL) is a protein able to bind to carbohydrate patterns on pathogen membranes; upon MBL binding, its associated serine protease MBL-associated serine protease type 2 (MASP2) is autoactivated, promoting the activation of complement via the lectin pathway. For both MBL2 and MASP2 genes, the frequencies of polymorphisms are extremely variable between different ethnicities, and this aspect has to be carefully considered when performing genetic studies. While polymorphisms in the MBL-encoding gene (MBL2) have been associated, depending upon ethnicity, with several diseases in different populations, little is known about the distribution of MASP2 gene polymorphisms in human populations. The aim of our study was thus to determine the frequencies of MBL2 (exon 1 and promoter) and MASP2 (p.D371Y) polymorphisms in a Brazilian population from Rio de Janeiro. A total of 294 blood donor samples were genotyped for 27 polymorphisms in the MBL2 gene by direct sequencing of a region spanning from the promoter polymorphism H/L rs11003125 to the rs1800451 polymorphism (at codon 57 in the first exon of the gene). Genotyping for MASP2 p.D371Y was carried out using fluorogenic probes. To our knowledge, this is the first study reporting the prevalence of the MASP2 p.D371Y polymorphism in a Brazilian population. The C allele frequency 39% is something intermediate between the reported 14% in Europeans and 90% in Sub-Saharan Africans. MBL2 polymorphisms frequencies were quite comparable to those previously reported for admixed Brazilians. Both MBL2 and MASP2 polymorphisms frequencies reported in our study for the admixed Brazilian population are somehow intermediate between those reported in Europeans and Africans, reflecting the ethnic composition of the southern Brazilian population, estimated to derive from an admixture of Caucasian (31%), African (34%) and Native American (33%) populations. In conclusion, our population genetic study describes the frequencies of MBL2 and MASP2 functional SNPs in a population from Rio de Janeiro, with the aim of adding new information concerning the distribution of these SNPs in a previously unanalysed Brazilian population, thus providing a new genetic tool for the evaluation of the association of MBL2 and MASP2 functional SNPs with diseases in Brazil, with particular emphasis on the state of Rio de Janeiro.

Baccharis subgen. Molina (Asteraceae) no estado do Rio de Janeiro, Brasil

Baccharis compreende ca. 340 espécies distribuídas nas Américas. O indumento em tufos diminutos, formado por tricomas com uma única célula basal, e as flores funcionalmente unissexuais são caracteres diagnósticos do gênero. No estado do Rio de Janeiro ocorrem 55 espécies de Baccharis. O trabalho apresenta os resultados de estudos taxonômicos de Baccharis subgen. Molina (Pers.) Heering para a flora fluminense. No estado, o subgênero está representado por 18 espécies pertencentes a quatro seções - Caulopterae (8 spp.), Molinae (4 spp.), Baccharidastrum (3 spp.) e Trinervatae (3 spp.). É apresentada uma chave para a identificação das seções e espécies e descrições morfológicas, ilustrações, dados de distribuição geográfica e ecologia. Três espécies são novos registros e cinco são excluídas da lista de espécies do Rio de Janeiro.

The Alliance for Progress and Housing Policy in Rio de Janeiro and Buenos Aires in the 1960s

This article explores the construction of publicly financed low-income housing complexes in Rio de Janeiro, Brazil, and Buenos Aires, Argentina, in the 1960s. These housing developments were possible thanks to the arrival of foreign economic and technical assistance from the Alliance for Progress. Urban scholars, politicians, diplomats and urbanists of the Americas sought to promote middle-class habits, mass consumption and moderate political behaviour, especially among the poor, by expanding access to homeownership and ‘decent’ living conditions for a burgeoning urban population. As a result, the history of low-income housing should be understood within broader transnational discourses and practices about the ‘modernization’ and ‘development’ of the urban poor.

O mal que se adivinha: polícia e menoridade no Rio de Janeiro (1910-1920). En: Avá, nº 16

O mal que se adivinha: polícia e menoridade no Rio de Janeiro ( 1 9 1 0 - 1 9 2 0 ) de Adriana de Resende Vianna es un estudio que se ubica en el campo de la antropología histórica . Aborda el proceso por el cual se construyó un personaje social - el ‘menor ’- a través de las prácticas cotidianas que la Policía del Distrito Federal de Río de Janeiro ejercía sobre un conjunto de individuos entre 1910 y 1920. Se trata de un escrito minucioso que intenta iluminar cómo al identificar individuos bajo el rótulo ‘menores’, atribuir varios significados al término e intervenir sobre el los se crea la existencia social de ese personaje, y al mismo tiempo se instituyen y legitiman los actores que realizan estas tareas.

Buarque, Cristovam. A desordem do progresso: o fim da era dos economistas e a construcao do futuro. Rio de Janeiro, Paz e Terra, 1990, 186 p.

Fil: Jalif de Bertranou, Clara Alicia.

Gravidez imprevista e aborto no Rio de Janeiro, Brasil: gênero e geração nos processos decisórios.

El artículo presenta resultados de la investigación HEXCA-Brasil que, por medio de entrevistas en profundidad, indagó la interrupción del embarazo en trayectorias biográficas de 31 mujeres y 28 hombres de camadas populares y medias, en diferentes franjas etarias (18 a 17 años y 40 a 49 años). Se abordan los procesos de negociación y toma de decisión acerca del aborto. Dichos procesos, condicionados por circunstancias sociales variadas, se han revalado portadores de temporalidades diversas, no lineales. Además del análisis de tales procesos de decisión se examinan las relaciones de género narradas por los informantes, así como las condiciones de la etapa vital en que tuvo lugar el evento de interrupción del embarazo. El contraste generacional ha permitido observar, en los estratos sociales indagados, cambios significativos en las relaciones familiares y de género; en las representaciones acerca de la maternidad, la paternidad y la reproducción; así como en los métodos abortivos y su accesibilidad en las últimas décadas. La perspectiva biográfica adoptada se mostró fecundidad al vincular del evento analizado con el trayecto de las experiencias sexuales, contraceptivas y reproductivas de los entrevistados.

Candido, Maria Regina (org). Práticas Alimentares no Mediterrâneo Antigo. Rio de Janeiro: NEA/UERJ, 2012. 333 p.

Resumen de la compilación a cargo de Maria Regina Candido (NEA-UERJ) en torno a las prácticas alimentares en el contexto del Mediterráneo Antiguo. La misma cuenta con la colaboración de dieciséis investigadores brasileños, portugueses y argentinos pertenecientes a universidades públicas y privadas de los respectivos países