A common contrast pooling rule for suppression within and between the eyes

Recent work has revealed multiple pathways for cross-orientation suppression in cat and human vision. In particular, ipsiocular and interocular pathways appear to assert their influence before binocular summation in human but have different (1) spatial tuning, (2) temporal dependencies, and (3) adaptation after-effects. Here we use mask components that fall outside the excitatory passband of the detecting mechanism to investigate the rules for pooling multiple mask components within these pathways. We measured psychophysical contrast masking functions for vertical 1 cycle/deg sine-wave gratings in the presence of left or right oblique (645 deg) 3 cycles/deg mask gratings with contrast C%, or a plaid made from their sum, where each component (i) had contrast 0.5Ci%. Masks and targets were presented to two eyes (binocular), one eye (monoptic), or different eyes (dichoptic). Binocular-masking functions superimposed when plotted against C, but in the monoptic and dichoptic conditions, the grating produced slightly more suppression than the plaid when Ci $ 16%. We tested contrast gain control models involving two types of contrast combination on the denominator: (1) spatial pooling of the mask after a local nonlinearity (to calculate either root mean square contrast or energy) and (2) "linear suppression" (Holmes & Meese, 2004, Journal of Vision 4, 1080–1089), involving the linear sum of the mask component contrasts. Monoptic and dichoptic masking were typically better fit by the spatial pooling models, but binocular masking was not: it demanded strict linear summation of the Michelson contrast across mask orientation. Another scheme, in which suppressive pooling followed compressive contrast responses to the mask components (e.g., oriented cortical cells), was ruled out by all of our data. We conclude that the different processes that underlie monoptic and dichoptic masking use the same type of contrast pooling within their respective suppressive fields, but the effects do not sum to predict the binocular case.

Calcitonin and calcitonin receptor-like receptors:common themes with family B GPCRs?

The calcitonin receptor (CTR) and calcitonin receptor-like receptor (CLR) are two of the 15 human family B (or Secretin-like) GPCRs. CTR and CLR are of considerable biological interest as their pharmacology is moulded by interactions with receptor activity-modifying proteins. They also have therapeutic relevance for many conditions, such as osteoporosis, diabetes, obesity, lymphatic insufficiency, migraine and cardiovascular disease. In light of recent advances in understanding ligand docking and receptor activation in both the family as a whole and in CLR and CTR specifically, this review reflects how applicable general family B GPCR themes are to these two idiosyncratic receptors. We review the main functional domains of the receptors; the N-terminal extracellular domain, the juxtamembrane domain and ligand interface, the transmembrane domain and the intracellular C-terminal domain. Structural and functional findings from the CLR and CTR along with other family B GPCRs are critically appraised to gain insight into how these domains may function. The ability for CTR and CLR to interact with receptor activity-modifying proteins adds another level of sophistication to these receptor systems but means careful consideration is needed when trying to apply generic GPCR principles. This review encapsulates current thinking in the realm of family B GPCR research by highlighting both conflicting and recurring themes and how such findings relate to two unusual but important receptors, CTR and CLR.

Age effect in generating mental images of buildings but not common objects

Imagining a familiar environment is different from imagining an environmental map and clinical evidence demonstrated the existence of double dissociations in brain-damaged patients due to the contents of mental images. Here, we assessed a large sample of young and old participants by considering their ability to generate different kinds of mental images, namely, buildings or common objects. As buildings are environmental stimuli that have an important role in human navigation, we expected that elderly participants would have greater difficulty in generating images of buildings than common objects. We found that young and older participants differed in generating both buildings and common objects. For young participants there were no differences between buildings and common objects, but older participants found easier to generate common objects than buildings. Buildings are a special type of visual stimuli because in urban environments they are commonly used as landmarks for navigational purposes. Considering that topographical orientation is one of the abilities mostly affected in normal and pathological aging, the present data throw some light on the impaired processes underlying human navigation.

Imagined intergroup contact and common ingroup identity:an integrative approach

We conducted two studies involving two different age groups (elementary school children and adults) aimed at integrating imagined contact and common ingroup identity models. In the first study, Italian elementary school children were asked to imagine interacting with an unknown immigrant peer as members of a common group. Results revealed that common ingroup imagined contact, relative to a control condition, improved outgroup helping intentions assessed 1 week and 2 weeks after the intervention. In the second study, common ingroup imagined contact led Italian university students to display higher intentions to have contact with immigrants compared to control conditions. In conclusion, results from both studies demonstrate that imagining an intergroup interaction as members of the same group strengthens the effects of imagined contact. These findings point to the importance of combining the common ingroup identity model and the imagined contact theory in order to increase the potentiality of prejudice reduction interventions.

Ellenőrzési aspektusok a vállalatok versenyképességének szemszögéből = Control aspects and competitiveness in business companies

Ez a műhelytanulmány a 2009-es versenyképesség kutatás során 317 vállalatra kiterjedő kérdőíves felmérés konkrét adataiból emeli ki az ellenőrzéssel, kontrollal összefüggő tényezőket és ezek eredményeit hasonlítja össze a hazai és nemzetközi szakirodalom ide vonatkozó elméleteivel. A kutatási kérdések arra irányulnak, hogy milyen részekből, feladatokból, tevékenységekből tevődnek össze a vezetők ellenőrzési feladatai, azok mikre terjednek ki, és mennyiben tekinthetők fejlettnek a versenyképes vállalatoknál. A műhelytanulmányban konkrétan a kontrolling eszköztár, a belső ill. pénzügyi ellenőrzés és kockázatkezelés, valamint a minőségirányítási sztenderdek, szabványok által megkövetelt ellenőrzési mechanizmusok vizsgálata történik a hazai, 50 főt meghaladó vállalkozások esetében. A műhelytanulmány a klasszikus kutatási jelentések sémájában készült, elméleti felvezetéssel és szakirodalmi áttekintéssel indít, majd második részében a konkrét versenyképesség adatbázis adatainak bemutatása történik a témában, végül összegzés, segítő szószedet és irodalomjegyzék zárja azt. _______ This workpaper is a report of controlmechanisms used by Hungarian companies. The latest stage of the Competitivness Research project started in 2009 during which data were collected from 317 Hungarian companies. Themes of this workpaper are controlmechanism, or controll-framework of the companies and connection between controlmechanism and competitiveness. Main elements of the research are: controlling aspects, internal and financial audits completed by managment including critical risks, audits according to ISO 9001:2008 standards or other standards, and the way these elements support or influence the competitiveness of the companies. The structure of this workpaper follows the common parts of other research reports. It begins with details of the theoretical background and presents main publications of the topic, than goes through several direct analisys and tests regarding the Hungarian competitiveness database of 2009. At the end the of the workpapaper a basic summary can be found with a glossary of explanations, and a bibliography of cited papers and publications.

Többéves pénzügyi keret vitája középről és a sor végéről – Magyarország és Lettország harcban a mezőgazdasági és kohéziós támogatásokért (Debate on the eu multiannual financial framework from the view of Hungary and Latvia)

Az Európai Bizottság 2011. júniusban nyilvánosságra hozott, a következő hétéves időszakot meghatározó pénzügyi keretéről szóló javaslatával elindult a tagállamok, illetve az intézmények közötti szakmai és politikai érvelés, az alkudozások sora. A két legfontosabb költségvetési tétel, a mezőgazdasági támogatások és a kohéziós források előnyös allokációja Magyarország és Lettország számára is kiemelt prioritás. A tárgyalások során Lettország érdeke az alacsony közvetlen mezőgazdasági támogatások emelése, míg Magyarország kedvező pozíciójának megtartásáért harcol. A kohéziós politikára tett Bizottsági javaslat mindkét ország számára hátrányos, így közös érdek a források összegének szinten tartása és a kedvezőtlen támogatási felső határ emelése. ______ Following the European Commission’s proposal on the next Multiannual Financial Framework was published in June 2011, tense debate started to defend national priorities. The proper allocation of the agricultural and cohesion founds is essential for both, Hungary and Latvia as well. Latvia’s objectives is to introduce fair direct payments to farmers, stipulating that the lowest payments must constitute at least 80 per cent of the average amount of the EU direct payments, while Hungary tries to defend its relatively favourable position by receiving almost the amount of the EU average. Common interest for Hungary and for Latvia in the EU budget talks is to retain cohesion financing at least at the current level and to change the unfavourable proposal on capping.

A turizmus magyar vonzerőiről (Hungarian tourist attractions)

A hazai turizmus gyakorlatával kapcsolatos vizsgálatok tapasztalatai nyomán az egri Eszterházy Károly Főiskola (EKF) turizmusmenedzsment-kurzusának oktatói célszerűnek ítélték a témára vonatkozó tananyag fejlesztését. A cikk szerzői azt remélik azonban, hogy az utóbbi munka egyes megállapításai minden, a gazdasági földrajz, a turizmus (idegenforgalom), a térségfejlesztés valamely szegmensével foglalkozó szakembernek, kiemelten: vezetőnek – s több más gazdasági ág illetékeseinek – az érdeklődésére számot tarthatnak, ezért ezekről jelen cikkben is beszámolnak. _____ In this article the authors reviewed first the different types of tourist attractions (destinations) and they analysed the common evaluation methods of their attractiveness (e.g. the possibilities and limits of the tourism statistics). Then they tried to display the existing information on the main Hungarian attractions and their attractiveness. In this study revealed that there exist no generally recognized list of the most visited attractions, and the real measures of their attractiveness are not known either. The authors emphasize that shaping a comprehensive concept on the above mentioned issue would highly contribute to the elaboration of a successful and achievable tourism strategy, thus it would be of great importance.