Executive Order Number Forty Six, January 5, 1993

Establish the TIM Council (Telecommunication and Informational Management)

Executive Order Number Forty Seven, March 29, 1993

Accepts offer of assignment of concurrent jurisdiction.

Executive Order Number Forty Eight, February 1994

Establish the Iowa Commission for National and Community Service

Executive Order Number Forty Nine, March 4, 1994

Establish the Telemedicine Advisory Council.

Executive Order Number Fifty, May 2, 1994

Establishs the Iowa Health Reform Transition Team. Rescinded by Executive Order #60.

Executive Order Number Sixty Eight, November 23, 1998

Prohabits use of all tobacco products in the areas of buildings under Governor's control in the State Capital Complex and all offices occupied by state government.

Executive Order Number Fifty Two, July 1, 1994

Replaces and rescinds Executive Order #35.

Executive Order Number Fifty Three, July 29, 1994

Eastablish an Iowa Workforce Development Council.

Executive Order Number Fifty Four, December 23, 1994

Replaces and rescinds Iowa Workforce Executive Order #39. Rescinded by Exectuive Order #62.

Executive Order Number Fifty Five, June 22, 1995

Appoints the Des Moines resident-in-charge for the U.S. Drug Enforcement Adminstration as a nonvoting ex-officio member of the Iowa Law Enforcement Academy Council.

Executive Order Number Fifty Six, December 18, 1995

Replaces and rescinds Executive Order #37.

Executive Order Number Fifty Seven, June 28, 1995

Directs Department of Personnel to develop policy that will assist in continuing efforts to maintain a violence-free workplace.

Executive Order Number Fifty Eight, July 1, 1995

Delegates the authority and responsibility for the Job Training Partnership Act to the Workforce Development Department(WDD). Replaces and rescinds Executive Order #24.

Decreased binding of peptides-MHC class I (pMHC) multimeric complexes to CD8 affects their binding avidity for the TCR but does not significantly impact on pMHC/TCR dissociation rate.

The CD8 coreceptor plays a crucial role in both T cell development in the thymus and in the activation of mature T cells in response to Ag-specific stimulation. In this study we used soluble peptides-MHC class I (pMHC) multimeric complexes bearing mutations in the CD8 binding site that impair their binding to the MHC, together with altered peptide ligands, to assess the impact of CD8 on pMHC binding to the TCR. Our data support a model in which CD8 promotes the binding of TCR to pMHC. However, once the pMHC/TCR complex is formed, the TCR dominates the pMHC/TCR dissociation rates. As a consequence of these molecular interactions, under physiologic conditions CD8 plays a key role in complex formation, resulting in the enhancement of CD8 T cell functions whose specificity, however, is determined by the TCR.

Executive Order Number Fifty Nine, September 30, 1996

Assings the responsibility of meeting State's requirement to eastablish a Human Resource Investment Council, in conformance with P.L. 102-367. Rescinds Executive Order #53.