Does anticipation of back pain predispose to back trouble?

Limb movement imparts a perturbation to the body. The impact of that perturbation is limited via anticipatory postural adjustments. The strategy by which the CNS controls anticipatory postural adjustments of the trunk muscles during limb movement is altered during acute back pain and in people with recurrent back pain, even when they are pain free. The altered postural strategy probably serves to protect the spine in the short term, but it is associated with a cost and is thought to predispose spinal structures to injury in the long term. It is not known why this protective strategy might occur even when people are pain free, but one possibility is that it is caused by the anticipation of back pain. In eight healthy subjects, recordings of intramuscular EMG were made from the trunk muscles during single and repetitive arm movements. Anticipation of experimental back pain and anticipation of experimental elbow pain were elicited by the threat of painful cutaneous stimulation. There was no effect of anticipated experimental elbow pain on postural adjustments. During anticipated experimental back pain, for single arm movements there was delayed activation of the deep trunk muscles and augmentation of at least one superficial trunk muscle. For repetitive arm movements, there was decreased activity and a shift from biphasic to monophasic activation of the deep trunk muscles and increased activity of superficial trunk muscles during anticipation of back pain. In both instances, the changes were consistent with adoption of an altered strategy for postural control and were similar to those observed in patients with recurrent back pain. We conclude that anticipation of experimental back pain evokes a protective postural strategy that stiffens the spine. This protective strategy is associated with compressive cost and is thought to predispose to spinal injury if maintained long term. © Guarantors of Brain 2004; all rights reserved

Respiratory and cardiovascular responses to hypoxia in the Australian lungfish

Simultaneous measurements of pulmonary blood flow (qPA), coeliacomesenteric blood flow (qCoA), dorsal aortic blood pressure (PDA), heart rate (fH) and branchial ventilation frequency (fv) were made in the Australian lungfish, /Neoceratodus forsteri, /during air breathing and aquatic hypoxia. The cho­linergic and adrenergic influences on the cardiovascular system were investigated during normoxia using pharmacological agents, and the presence of catecholamines and serotonin in different tissues was investi­gated using histochemistry. Air breathing rarely occurred during normoxia but when it did, it was always associated with increased pulmonary blood flow. The pulmonary vasculature is influenced by both a cho­linergic and adrenergic tonus whereas the coeliacomesenteric vasculature is influenced by a β-adrenergic vasodilator mechanism. No adrenergic nerve fibers could be demonstrated in /Neoceratodus /but catecholamine-containing endothelial cells were found in the atrium of the heart. In addition, serotonin-­immunoreactive cells were demonstrated in the pulmonary epithelium. The most prominent response to aquatic hypoxia was an increase in gill breathing frequency followed by an increased number of air breaths together with increased pulmonary blood flow. It is clear from the present investigation that /Neoceratodus /is able to match cardiovascular performance to meet the changes in respiration during hypoxia.

Stairs to upper level, Brannigan House, St Lucia, Brisbane

Stairs to upper bedroom/studio spaces. Kitchen and central deck on left.

Window, Brannigan House, St Lucia, Brisbane

Fitted with external timber blind, South-West elevation.

North-West elevation, Brannigan House, St Lucia, Brisbane

Facing front of site. Carport underneath house, entry steps on left.

South-East elevation, Brannigan House, St Lucia, Brisbane

Facing rear of site.

South-East elevation, Brannigan House, St Lucia, Brisbane

Facing rear of site.

Balustrade detail, Brannigan House, St Lucia, Brisbane

Rigging screw tensioners to balustrade wire, central deck (North-East elevation).

Deck, Brannigan House, St Lucia, Brisbane

As seen from living room interior, looking through to deck and kitchen beyond.

Balustrading to deck, Brannigan House, St Lucia, Brisbane

Curved steel and stainless steel wire balustrade to central deck area (North-East elevation).

Kitchen servery to deck, Brannigan House, St Lucia, Brisbane

Corner of kitchen opens to deck via a series of folding windows.

Lower level floor plan, Brannigan House, St Lucia, Brisbane

Hand-drawn floor plan.

View from Sunshine Beach House, Sunshine Coast

View to ocean from upper level viewing deck.