992 resultados para hyperpolarized, xenon, Polarizer, GE180, T1 xenon
Resumo:
A toxidez por ferro o distrbio nutricional de maior ocorrncia em arroz (Oryza sativa L.) cultivado em sistemas alagados, derivada da quantidade excessiva de ons ferrosos (Fe2+) gerados pela reduo de xidos de ferro em solos alagados. Em experimento conduzido em casa de vegetao, foram avaliados os efeitos de manejos da gua de irrigao na dinmica de reduo de um Planossolo e na manifestao da toxidez por ferro em arroz. Os tratamentos dispostos em blocos completos ao acaso com quatro repeties constaram de cinco manejos da gua: T1- incio do alagamento no estdio V2-V3 do arroz; T2- incio do alagamento no estdio V6-V7; T3- T1 e drenagem no estdio V10-V11; T4- T2 e drenagem no estdio V10-V11; e T5- T1 e drenagens nos estdios V7-V8 e V10-V11. O atraso do incio do alagamento para o estdio V6-V7 do arroz manteve os valores do Eh da soluo do solo mais elevados, promovendo menor disponibilidade de Fe2+ na soluo do solo e deslocando a mxima liberao de Fe2+ na soluo do solo para estdios fenolgicos mais avanados do arroz. A realizao de drenagens ao longo do ciclo vegetativo do arroz promoveu a reoxidao do solo, que ocasionou o aumento dos valores de Eh e reduo da concentrao de Fe2+ na soluo do solo. O uso de drenagens durante o perodo vegetativo do arroz foi eficiente no controle da toxidez por excesso de ferro, em arroz cultivado em solo alagado.
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O cultivo do feijoeiro em sistema plantio direto (SPD) tem aumentado de forma marcante no pas. Neste contexto, para adubaes mais racionais, fundamental conhecer as exigncias nutricionais da cultura quando cultivada em SPD recm-implantado ou consolidado, j que o tempo de implantao do sistema pode alterar a disponibilidade de nutrientes e a resposta das culturas adubao nitrogenada. Objetivou-se avaliar a extrao e exportao de nutrientes pelo feijoeiro em razo da adubao nitrogenada, em solo sob SPD recm-implantado ou consolidado. O experimento foi conduzido por dois anos agrcolas, em um Nitossolo Vermelho distrfico, no municpio de Botucatu, SP. O delineamento experimental foi em blocos ao acaso, em esquema de parcelas subdivididas, com quatro repeties. As parcelas foram formadas por reas sob SPD com diferentes tempos de adoo, e as subparcelas constitudas por quatro formas de aplicao do nitrognio (N) na cultura do feijo (T0: controle, sem aplicao de N; T1: 60 kg ha-1 na pr-semeadura; T2: 60 kg ha-1 aplicado em cobertura no estdio V4; e T3: 60 kg ha-1 na pr-semeadura + 60 kg ha-1 em cobertura). Foram avaliados: matria seca da parte area, concentrao e acmulo de nutrientes na parte area, produtividade de gros e concentraes e exportao de nutrientes nos gros. O tempo que a rea permaneceu sob SPD no influenciou a produtividade, a nutrio e nem mesmo a resposta da cultura do feijo adubao nitrogenada. A aplicao de N, especialmente em pr-semeadura, proporcionou maiores acmulos de matria seca e nutrientes pela cultura do feijo. As concentraes de nutrientes nos gros foram pouco influenciadas pela adubao nitrogenada. As maiores produtividades de gros e exportaes de nutrientes foram proporcionadas pela aplicao de N em duas pocas (pr-semeadura e em cobertura) ou apenas em cobertura.
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RESUME BUT Cette tude a t mene sur le suivi de patients traits pour un glioblastome nouvellement diagnostiqu. Son objectif a t de dterminer l'impact des squences de perfusion et de diffusion en imagerie par rsonance magntique (IRM). Un intrt particulier a t port au potentiel de ces nouvelles techniques d'imagerie dans l'anticipation de la progression de la maladie. En effet, l'intervalle de temps libre de progression est une mesure alternative de pronostic frquemment utilise. MATERIEL ET METHODE L'tude a port sur 41 patients participant un essai clinique de phase II de traitement par temozolomide. Leur suivi radiologique a comport un examen IRM dans les 21 28 jours aprs radiochimiothrapie et tous les 2 mois par la suite. L'valuation des images s'est faite sur la base de l'valuation de l'effet de masse ainsi que de la mesure de la taille de la lsion sur les images suivantes : T1 avec produit de contraste, T2, diffusion, perfusion. Afin de dterminer la date de progression de la maladie, les critres classiques de variation de taille adjoints aux critres cliniques habituels ont t utiliss. RESULAT 311 examens IRM ont t revus. Au moment de la progression (32 patients), une rgression multivarie selon Cox a permis de dterminer deux paramtres de survie : diamtre maximal en T1 (p>0.02) et variation de taille en T2 (p<0.05). L'impact de la perfusion et de la diffusion n'a pas t dmontr de manire statistiquement significative. CONCLUSION Les techniques de perfusion et de diffusion ne peuvent pas tre utilises pour anticiper la progression tumorale. Alors que la prise de dcision au niveau thrapeutique est critique au moment de la progression de la maladie, l'IRM classique en T1 et en T2 reste la mthode d'imagerie de choix. De manire plus spcifique, une prise de contraste en T1 suprieure 3 cm dans son plus grand diamtre associe un hypersignal T2 en augmentation forment un marqueur de mauvais pronostic.
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The construction of a soil after surface coal mining involves heavy machinery traffic during the topographic regeneration of the area, resulting in compaction of the relocated soil layers. This leads to problems with water infiltration and redistribution along the new profile, causing water erosion and consequently hampering the revegetation of the reconstructed soil. The planting of species useful in the process of soil decompaction is a promising strategy for the recovery of the soil structural quality. This study investigated the influence of different perennial grasses on the recovery of reconstructed soil aggregation in a coal mining area of the Companhia Riograndense de Minerao, located in Candiota-RS, which were planted in September/October 2007. The treatments consisted of planting: T1- Cynodon dactylon cv vaquero; T2 - Urochloa brizantha; T3 - Panicum maximun; T4 - Urochloa humidicola; T5 - Hemarthria altissima; T6 - Cynodon dactylon cv tifton 85. Bare reconstructed soil, adjacent to the experimental area, was used as control treatment (T7) and natural soil adjacent to the mining area covered with native vegetation was used as reference area (T8). Disturbed and undisturbed soil samples were collected in October/2009 (layers 0.00-0.05 and 0.10-0.15 m) to determine the percentage of macro- and microaggregates, mean weight diameter (MWD) of aggregates, organic matter content, bulk density, and macro- and microporosity. The lower values of macroaggregates and MWD in the surface than in the subsurface layer of the reconstructed soil resulted from the high degree of compaction caused by the traffic of heavy machinery on the clay material. After 24 months, all experimental grass treatments showed improvements in soil aggregation compared to the bare reconstructed soil (control), mainly in the 0.00-0.05 m layer, particularly in the two Urochloa treatments (T2 and T4) and Hemarthria altissima (T5). However, the great differences between the treatments with grasses and natural soil (reference) indicate that the recovery of the pre-mining soil structure could take decades.
Resumo:
A adoo do plantio direto na regio subtropical mida do Brasil, fundamentada apenas em dois preceitos da agricultura conservacionista - mobilizao de solo restrita linha de semeadura e manuteno de resduos culturais na superfcie do solo -, tem induzido estratificao de atributos qumicos do solo na camada de 0-20 cm profundidade e degradao fsica da camada subsuperficial (entre aproximadamente 5-20 cm de profundidade), que podem contribuir para frustraes de safras agrcolas, quando da ocorrncia de estiagens. O objetivo deste trabalho foi avaliar o efeito residual de uma semeadora/adubadora, equipada com elemento rompedor de solo tipo haste sulcadora, atuando em quatro profundidades para a semeadura de milho (Zea mays L.), na mitigao de problemas de ordem fsica e qumica, em um Latossolo Vermelho distrfico hmico, manejado em plantio direto h mais de 10 anos. Os tratamentos avaliados foram: T1 = hastes sulcadoras atuando at 5 cm de profundidade; T2 = hastes sulcadoras atuando at 10 cm de profundidade; T3 = hastes sulcadoras atuando at 15 cm de profundidade; e T4 = hastes sulcadoras atuando at 17 cm de profundidade. O efeito desses tratamentos sobre os atributos fsicos do solo foi avaliado pela tcnica do perfil cultural associada determinao da densidade, porosidade total, macroporosidade e resistncia do solo penetrao, aos oito e 12 meses, aps a semeadura da cultura de milho. Sobre os atributos qumicos, esses efeitos foram avaliados pela determinao de pH em H2O, P e K disponveis, Ca, Mg e Al trocveis, acidez potencial e matria orgnica, em amostras de solo coletadas em camadas de 2,5 cm de espessura, de 0-22,5 cm de profundidade. A utilizao da semeadora/adubadora, equipada com elemento rompedor de solo tipo haste sulcadora, evidenciou-se eficaz em mitigar os problemas fsicos e qumicos do solo, tanto aos oito como aos 12 meses aps a operao de semeadura.
Resumo:
A disponibilidade de nutrientes durante o ano pode influenciar o desempenho da nogueira-macadmia (Macadamia integrifolia). Contudo, no existem informaes sobre a resposta dessa cultura ao parcelamento da adubao nas condies brasileiras. O objetivo deste trabalho foi avaliar a influncia do parcelamento da adubao mineral na nutrio, produtividade e qualidade de frutos da nogueira-macadmia. O experimento foi conduzido, durante trs anos agrcolas, num Latossolo Vermelho, em Jaboticabal, SP. O delineamento experimental foi de blocos casualizados, com cinco repeties. O experimento foi constitudo por quatro formas de parcelamento da adubao NPK (T1 - uma nica aplicao, em outubro; T2 - duas aplicaes, em outubro e dezembro; T3 - trs aplicaes, em outubro, dezembro e fevereiro; e T4 - quatro aplicaes, em outubro, dezembro, fevereiro e abril). O parcelamento da adubao NPK proporcionou maiores teores de N nas folhas que a aplicao em dose nica, mas no interferiu nos teores dos demais nutrientes. A produtividade da nogueira-macadmia foi incrementada de forma similar com o parcelamento da adubao NPK em duas, trs ou quatro vezes, entre outubro e abril, em comparao aplicao nica em outubro. A taxa de recuperao de amndoas no foi interferida pelo parcelamento da adubao NPK.
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Tat activates transcription by interacting with Sp1, NF-kappaB, positive transcription elongation factor b, and trans-activator-responsive element (TAR). Tat and Sp1 play major roles in transcription by protein-protein interactions at human immunodeficiency virus, type 1 (HIV-1) long terminal repeat. Sp1 activates transcription by interacting with cyclin T1 in the absence of Tat. To disrupt the transcription activation by Tat and Sp1, we fused Sp1-inhibiting polypeptides, zinc finger polypeptide, and the TAR-binding mutant Tat (TatdMt) together. A designed or natural zinc finger and Tat mutant fusion was used to target the fusion to the key regulatory sites (GC box and TAR) on the long terminal repeat and nascent short transcripts to disrupt the molecular interaction that normally result in robust transcription. The designed zinc finger and TatdMt fusions were targeted to the TAR, and they potently repressed both transcription and replication of HIV-1. The Sp1-inhibiting POZ domain, TatdMt, and zinc fingers are key functional domains important in repression of transcription and replication. The designed artificial zinc fingers were targeted to the high affinity Sp1-binding site, and by being fused with TatdMt and POZ domain, they strongly block both Sp1-cyclin T1-dependent transcription and Tat-dependent transcription, even in the presence of excess expressed Tat.
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The action of rain and surface runoff together are the active agents of water erosion, and further influences are the soil type, terrain, soil cover, soil management, and conservation practices. Soil water erosion is low in the no-tillage management system, being influenced by the amount and form of lime and fertilizer application to the soil, among other factors. The aim was to evaluate the effect of the form of liming, the quantity and management of fertilizer application on the soil and water losses by erosion under natural rainfall. The study was carried out between 2003 and 2013 on a Humic Dystrupept soil, with the following treatments: T1 - cultivation with liming and corrective fertilizer incorporated into the soil in the first year, and with 100 % annual maintenance fertilization of P and K; T2 - surface liming and corrective fertilization distributed over five years, and with 75 % annual maintenance fertilization of P and K; T3 - surface liming and corrective fertilization distributed over three years, and with 50 % annual maintenance fertilization of P and K; T4 - surface liming and corrective fertilization distributed over two years, and with 25 % annual maintenance fertilization of P and K; T5 - fallow soil, without liming or fertilization. In the rotation the crops black oat (Avena strigosa ), soybean (Glycine max ), common vetch (Vicia sativa ), maize (Zea mays ), fodder radish (Raphanus sativus ), and black beans (Phaseolus vulgaris ). The split application of lime and mineral fertilizer to the soil surface in a no-tillage system over three and five years, results in better control of soil losses than when split in two years. The increase in the amount of fertilizer applied to the soil surface under no-tillage cultivation increases phytomass production and reduces soil loss by water erosion. Water losses in treatments under no-tillage cultivation were low in all crop cycles, with a similar behavior as soil losses.
Resumo:
Na quantificação do intervalo hídrico ótimo (IHO), são utilizados diferentes limites críticos de resistência à penetração (RP) e umidade na capacidade de campo (θCC). Para solos agrícolas, esses valores estão sendo documentados na literatura. Entretanto, para solos construídos após mineração de carvão, constata-se grande lacuna de informações. O objetivo deste trabalho foi quantificar a faixa de variação do intervalo hídrico ótimo de um solo construído sob diferentes plantas de cobertura na área de mineração de carvão de Candiota, sul do Brasil, considerando diferentes limites críticos de umidade do solo na capacidade de campo e de resistência à penetração. Foram avaliadas no experimento, em blocos casualizados com quatro repetições, as seguintes plantas de cobertura: Hemártria (Hemarthria altissima (Poir.) Stapf & C. E. Hubbard), tratamento 1 (T1); Pensacola (Paspalum notatum Flüggé), tratamento 2 (T2); Grama Tifton (Cynodon dactilon (L.) Pers.), tratamento 3 (T3); Controle (Urochloa brizantha (Hochst.) Stapf), tratamento 4 (T4); e sem plantas de cobertura, tratamento 5 (T5). Para determinar o IHO, foram utilizados diferentes valores críticos de θCC referentes às tensões de 0,006; 0,01; e 0,033 MPa e RP de 1,5; 2,0; 2,5; e 3,0 MPa, mantendo-se sempre constante a umidade do solo no ponto de murcha permanente (θPMP) como sendo igual ao valor retido na tensão de 1,5 MPa e a umidade do solo em que a porosidade de aeração (PA) é de 10 %. A faixa de variação do IHO foi maior no solo construído cultivado com Urochloa brizantha; e a menor com Pensacola, independentemente dos limites críticos de θCC e de RP. Os limites críticos de θCC e de RP utilizados na definição do IHO originaram diferentes valores de densidade critica (Dsc) para o solo construído sob diferentes plantas de cobertura. Os menores e maiores valores de Dsc foram obtidos quando utilizados como limites críticos na definição do IHO, o θCC = 0,033 MPa e a RP = 3 MPa. O solo construído cultivado com Urochloa brizantha e Hemártria apresentou valor de Ds muito próximo ao de Dsc.
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PURPOSE: Squamous cell carcinoma of larynx with subglottic extension (sSCC) is a rare location described to carry a poor prognosis. The aim of this study was to analyze outcomes and feasibility of larynx preservation in sSCC patients. PATIENTS AND METHODS: Between 1996 and 2012, 197patients with sSCC were treated at our institution and included in the analysis. Stage III-IV tumors accounted for 76 %. Patients received surgery (62 %), radiotherapy (RT) (18 %), or induction chemotherapy (CT) (20 %) as front-line therapy. RESULTS: The 5-year actuarial overall survival (OS), locoregional control (LRC), and distant control rate were 59 % (95 % CI 51-68), 83 % (95 % CI 77-89), and 88 % (95 % CI 83-93), respectively, with a median follow-up of 54.4 months. There was no difference in OS and LRC according to front-line treatments or between primary subglottic cancer and glottosupraglottic cancers with subglottic extension. In the multivariate analysis, age > 60 years and positive N stage were the only predictors for OS (HR 2, 95 % CI 1.2-3.6; HR1.9, 95 % CI 1-3.5, respectively). A lower LRC was observed for T3 patients receiving a larynx preservation protocol as compared with those receiving a front-line surgery (HR 14.1, 95 % CI 2.5-136.7; p = 0.02); however, no difference of ultimate LRC was observed according to the first therapy when including T3 patients who underwent salvage laryngectomy (p = 0.6). In patients receiving a larynx preservation protocol, the 5-year larynx-preservation rate was 55 % (95 % CI 43-68), with 36 % in T3 patients. The 5-year larynx preservation rate was 81 % (95 % CI 65-96) and 35 % (95 % CI 20-51) for patients who received RT or induction CT as a front-line treatment, respectively. CONCLUSION: Outcomes of sSCC are comparable with other laryngeal cancers when managed with modern therapeutic options. Larynx-preservation protocols could be a suitable option in T1-T2 (RT or chemo-RT) and selected T3 sSCC patients (induction CT).
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After open coal mining, soils are “constructed”, which usually contain low levels and quality of organic matter (OM). Therefore, the use of plant species for revegetation and reclamation of degraded areas is essential. This study evaluated the distribution of carbon (C) in the chemical fractions as well as the chemical characteristics and humification degree of OM in a soil constructed after coal mining under cultivation of perennial grasses. The experiment was established in 2003 with the following treatments: Hemarthria altissima (T1), Paspalum notatum (T2), Cynodon dactilon (T3), Urochloa brizantha (T4), bare constructed soil (T5), and natural soil (T6). In 2009, soil samples were collected from the 0.00-0.03 m layer and the total organic carbon stock (TOC) and C stock in the chemical fractions: acid extract (CHCl), fulvic acid (CFA), humic acid (CHA), and humin (CHU) were determined. The humic acid (HA) fraction was characterized by infrared spectroscopy and the laser-induced fluorescence index (ILIF) of OM was also calculated. After six years, differences were only observed in the CHA stocks, which were highest in T1 (0.89 Mg ha-1) and T4 (1.06 Mg ha-1). The infrared spectra of HA in T1, T2 and T4 were similar to T6, with greater contribution of aliphatic organic compounds than in the other treatments. In this way, ILIF decreased in the sequence T5>T3>T4>T1>T2>T6, indicating higher OM humification in T3 and T5 and more labile OM in the other treatments. Consequently, the potential of OM quality recovery in the constructed soil was greatest in treatments T1 and T4.
Resumo:
Soils constructed after mining often have low carbon (C) stocks and low quality of organic matter (OM). Cover crops are decisive for the recovery process of these stocks, improving the quality of constructed soils. Therefore, the goal of this study was to evaluate the effect of cover crops on total organic C (TOC) stocks, C distribution in physical fractions of OM and the C management index (CMI) of a soil constructed after coal mining. The experiment was initiated in 2003 with six treatments: Hemarthria altissima (T1), Paspalum notatum (T2), Cynodon dactylon (T3), Urochloa brizantha (T4), bare constructed soil (T5), and natural soil (T6). Soil samples were collected in 2009 from the 0.00-0.03 m layer, and the TOC and C stocks in the physical particle size fractions (carbon in the coarse fraction - CCF, and mineral-associated carbon - MAC) and density fractions (free light fraction - FLF; occluded light fraction - OLF, and heavy fraction - HF) of OM were determined. The CMI components: carbon pool index (CPI), lability (L) and lability index (LI) were estimated by both fractionation methods. No differences were observed between TOC, CCF and MAC stocks. The lowest C stocks in FLF and OLF fractions were presented by T2, 0.86 and 0.61 Mg ha-1, respectively. The values of TOC stock, C stock in physical fractions and CMI were intermediate, greater than T5 and lower than T6 in all treatments, indicating the partial recovery of soil quality. As a result of the better adaptation of the species Hemarthria and Brizantha, resulting in greater accumulation of labile organic material, the CPI, L, LI and CMI values were higher in these treatments, suggesting a greater potential of these species for recovery of constructed soils.
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ABSTRACT The large production of sewage sludge (SS), especially in large urban centers, has led to the suggestion of using this waste as fertilizer in agriculture. The economic viability of this action is great and contributes to improve the environment by cycling the nutrients present in this waste, including high contents of organic matter and plant nutrients. This study evaluated the chemical and biochemical properties of Dystrophic and EutroferricLatossolos Vermelhos (Oxisols) under corn and after SS application at different rates for 16 years. The field experiment was carried out in Jaboticabal, So Paulo State, Brazil, using a randomized block design with four treatments and five replications. Treatments consisted of control - T1 (mineral fertilization, without SS application), 5 Mg ha-1 SS - T2, 10 Mg ha-1 SS - T3, and 20 Mg ha-1 SS - T4 (dry weight base). The data were submitted to variance analysis and means were compared by the Duncan test at 5 %. Sewage sludge increased P extracted by resin in both theLatossolos Vermelhos, Dystrophic and Eutroferric, and the organic matter content in the Dystrophic Latossolo Vermelho. The waste at the rate 20 Mg ha-1 on a dry weight basis promoted increases in acid phosphatase activity in Eutroferric Latossolo Vermelho, basal respiration and metabolic quotient in DystrophicLatossolo Vermelho. The rate 20 Mg ha-1 sewage sludge on a dry weight basis did not alter the soil microbial biomass in both the Latossolos Vermelhos; in addition, it improved corn yields without inducing any symptoms of phytotoxicity or nutrient deficiency in the plants.
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ABSTRACT The expansion of the sugarcane industry in Brazil has intensified the mechanization of agriculture and caused effects on the soil physical quality. The purpose of this study was to evaluate the limiting water range and soil bearing capacity of a Latossolo Vermelho distrofrrico tpico (Rhodic Hapludox) under the influence of different tractor-trailers used in mechanical sugarcane harvesting. The experiment was arranged in a randomized block design with five replications. The treatments consisted of green sugarcane harvesting with: harvester without trailer (T1); harvester with two trailers with a capacity of 10 Mg each (T2); harvester with trailer with a capacity of 20 Mg (T3) and harvester and truck with trailer with a capacity of 20 Mg (10 Mg per compartment) (T4). The least limiting water range and soil bearing capacity were evaluated. The transport equipment to remove the harvested sugarcane from the field (trailer) at harvest decreased the least limiting water range, reducing the structural soil quality. The truck trailer caused the greatest impact on the soil physical properties studied. The soil load bearing capacity was unaffected by the treatments, since the pressure of the harvester (T1) exceeded the pre-consolidation pressure of the soil.
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ABSTRACT Increasing attention has recently been given to sweet sorghum as a renewable raw material for ethanol production, mainly because its cultivation can be fully mechanized. However, the intensive use of agricultural machinery causes soil structural degradation, especially when performed under inadequate conditions of soil moisture. The aims of this study were to evaluate the physical quality of aLatossolo Vermelho Distrofrrico (Oxisol) under compaction and its components on sweet sorghum yield forsecond cropsowing in the Brazilian Cerrado (Brazilian tropical savanna). The experiment was conducted in a randomized block design, in a split plot arrangement, with four replications. Five levels of soil compaction were tested from the passing of a tractor at the following traffic intensities: 0 (absence of additional compaction), 1, 2, 7, and 15 passes over the same spot. The subplots consisted of three different sowing times of sweet sorghum during the off-season of 2013 (20/01, 17/02, and 16/03). Soil physical quality was measured through the least limiting water range (LLWR) and soil water limitation; crop yield and technological parameters were also measured. Monitoring of soil water contents indicated a reduction in the frequency of water content in the soil within the limits of the LLWR (Fwithin) as agricultural traffic increased (T0 = T1 = T2>T7>T15), and crop yield is directly associated with soil water content. The crop sown in January had higher industrial quality; however, there was stalk yield reduction when bulk density was greater than 1.26 Mg m-3, with a maximum yield of 50 Mg ha-1 in this sowing time. Cultivation of sweet sorghum as a second crop is a promising alternative, but care should be taken in cultivation under conditions of pronounced climatic risks, due to low stalk yield.