A marginalised Markov Chain Monte Carlo approach for model based analysis of EEG data

The work presented in this paper focuses on fitting of a neural mass model to EEG data. Neurophysiology inspired mathematical models were developed for simulating brain's electrical activity imaged through Electroencephalography (EEG) more than three decades ago. At the present well informative models which even describe the functional integration of cortical regions also exists. However, a very limited amount of work is reported in literature on the subject of model fitting to actual EEG data. Here, we present a Bayesian approach for parameter estimation of the EEG model via a marginalized Markov Chain Monte Carlo (MCMC) approach.

Composite spectral shape descriptor

Effective spectral representations of shape region are proposed in literature. On the other hand, a significant spatial characteristic of shape region is shape contour because human beings discriminate shapes mainly by their contour features. It is proposed that a descriptor is obtained by complementing the spectral representation of shape region with the spectral representation of shape contour. Such a descriptor, obtained by explicitly combining two (or more) descriptors is termed composite descriptor. A composite descriptor is proposed; the effectiveness of the composite descriptor to represent shape region is evaluated.

Optimization of bypass graft using FSI numerical method

It is well documented in literature that the coronary artery bypass graft is normally fail after a short period of time, due to the development of plaque known as intimal hyperplasia within the graft. Various in vivo and in vitro studies have linked the development of intimal hyperplasia to the abnormal hemodynamics and compliance mismatch. Therefore, it is essential to fully understand the relationship between the hemodynamics inside the coronary artery bypass and its mechanical and geometrical characteristics under the correct physiological conditions. In this work, hemodynamic of the bypass graft is studied numerically. The effect of the host and graft diameters ratio, the angle of anastomosis and the graft configuration on the local flow patterns and the distribution of wall shear stress are examined. The pulsatile waveforms boundary conditions are adopted from in vivo measurement data to study the hemodynamics of composite grafts namely Consequence and Y grafting in terms temporal and spatial distributions of the blood flows. Moreover, various non-Newtonian and Newtonian models of blood have been carried out to examine the numerical simulation of blood flow in stenosis artery. The results are presented and discussed for various operating conditions.

The novel as social satire: 60 years later, the wind done gone and the limitations of fair use

The absence of the doctrine of fair use from Australian copyright law has been a bone of contention in Australia after the Australia-United States Free Trade Agreement (FTA). As the Australian government reformed the Copyright Act 1968 (Cth) in the aftermath of the FTA it eschewed the option of adopting fair use. Instead, Australia chose to incorporate a version of fair use into its existing fair dealing framework. Accordingly, the Copyright Amendment Act 2006 (Cth) inserted ss 41A and 103AA into the Copyright Act. These provisions provide that a fair dealing with a copyright protected work does not constitute an infringement if it is done for the purposes of parody or satire. These provisions codify part of the ratio of the United States Supreme Court in the seminal case of Campbell v Acuff Rose Music. However, the parameters of these new provisions are unexplored and the sparse nature of fair dealing jurisprudence means that the true meaning of the provisions is unclear. Moreover, two cases from the United States, SunTrust Bank v Houghton Mifflin and Salinger v Colting, underline just how important it is to have legal rules that protect literary ‘re-writes’. Both cases involved authors using an original novel to ‘write back’ to the original author and the broader culture. ‘Writing back’ or the ‘re-write’ has a firm basis in literature. It adds something invaluable to our culture. The key question is whether our legal landscape can allow it to flourish. This paper examines the interaction between fair use and literary re-writes.

Girls' school stories, 1749-1929

As part of the ongoing project of retrieving women writers from the margins of literary and cultural history, scholars of literature, history, and gender studies are increasingly exploring and interrogating girls’ print culture. School stories, in particular, are generating substantial scholarly interest because of their centrality to the history of girls’ reading, their engagement with cultural ideas about the education and socialization of girls, and their enduring popularity with book collectors. However, while serious scholars have begun to document the vast corpus of English-language girls’ school stories, few scholarly editions or facsimile editions of these novels and short stories are readily available.

A history of the lie of innocence: sons who become orphans

This thesis deals with a history of the lie of innocence, its inception in biblical representation and its development in literary representations from the eighteenth century to contemporary times. The aim is to disclose the way the lie functioned across time both in Christian societies and in the secular ones in their wake.

Network dynamics of mobile social networks

With the rapid development of smartphones and mobile Internet technology, we witness an overwhelming growth of mobile social networks (MSN), which is a type of social network, forming virtual communities among people with similar interests or commonalities. In MSNs, users play a crucial role for their development, deployment and success. Understanding the MSN user behavior therefore attracts interests of different entities - ISPs, service providers, and researchers. However, it is hard to gather a comprehensive real data set, little is known and even less has been published about MSN user activities. In this paper, we focus on analyzing MSN user behavior from the perspective of ISP network, which is seldom reported in literature. Based on the real data set collected from the mobile network gateway of a major mobile carrier who has more than five million subscribers, we present an in-depth user behavior analysis of four popular social networks. We study the MSN user behavior from six aspects: user requests, active online time, sessions, inter-session, the number of requests in a session, and inter-request. We found that power law and lognormal are two popular features of the studied objects, and exposed some interesting findings as well. We hope our work could be helpful for ISPs, MSN content providers, and researchers. © 2014 IEEE.

Actor-Network Theory (ANT) based visualisation of socio-technical facets of RFID technology translation: an Australian hospital scenario

In the early 2000s, Information Systems researchers in Australia had begun to emphasise socio-technical approaches in innovation adoption of technologies. The ‘essentialist' approaches to adoption (for example, Innovation Diffusion or TAM), suggest an essence is largely responsible for rate of adoption (Tatnall, 2011) or a new technology introduced may spark innovation. The socio-technical factors in implementing an innovation are largely flouted by researchers and hospitals. Innovation Translation is an approach that purports that any innovation needs to be customised and translated in to context before it can be adopted. Equally, Actor-Network Theory (ANT) is an approach that embraces the differences in technical and human factors and socio-professional aspects in a non-deterministic manner. The research reported in this paper is an attempt to combined the two approaches in an effective manner, to visualise the socio-technical factors in RFID technology adoption in an Australian hospital. This research investigation demonstrates RFID technology translation in an Australian hospital using a case approach (Yin, 2009). Data was collected using a process of focus groups and interviews, analysed with document analysis and concept mapping techniques. The data was then reconstructed in a ‘movie script' format, with Acts and Scenes funnelled to ANT informed abstraction at the end of each Act. The information visualisation at the end of each Act using ANT informed Lens reveal the re-negotiation and improvement of network relationships between the people (factors) involved including nurses, patient care orderlies, management staff and non-human participants such as equipment and technology. The paper augments the current gaps in literature regarding socio-technical approaches in technology adoption within Australian healthcare context, which is transitioning from non-integrated nearly technophobic hospitals in the last decade to a tech-savvy integrated era. More importantly, the ANT visualisation addresses one of the criticisms of ANT i.e. its insufficiency to explain relationship formations between participants and over changes of events in relationship networks (Greenhalgh & Stones, 2010).

Multivariate adaptive autoregressive modeling and kalman filtering for motor imagery BCI

Adaptive autoregressive (AAR) modeling of the EEG time series and the AAR parameters has been widely used in Brain computer interface (BCI) systems as input features for the classification stage. Multivariate adaptive autoregressive modeling (MVAAR) also has been used in literature. This paper revisits the use of MVAAR models and propose the use of adaptive Kalman filter (AKF) for estimating the MVAAR parameters as features in a motor imagery BCI application. The AKF approach is compared to the alternative short time moving window (STMW) MVAAR parameter estimation approach. Though the two MVAAR methods show a nearly equal classification accuracy, the AKF possess the advantage of higher estimation update rates making it easily adoptable for on-line BCI systems.

Linear approximation of Karnik-Mendel type reduction algorithm

Karnik-Mendel (KM) algorithm is the most used and researched type reduction (TR) algorithm in literature. This algorithm is iterative in nature and despite consistent long term effort, no general closed form formula has been found to replace this computationally expensive algorithm. In this research work, we demonstrate that the outcome of KM algorithm can be approximated by simple linear regression techniques. Since most of the applications will have a fixed range of inputs with small scale variations, it is possible to handle those complexities in design phase and build a fuzzy logic system (FLS) with low run time computational burden. This objective can be well served by the application of regression techniques. This work presents an overview of feasibility of regression techniques for design of data-driven type reducers while keeping the uncertainty bound in FLS intact. Simulation results demonstrates the approximation error is less than 2%. Thus our work preserve the essence of Karnik-Mendel algorithm and serves the requirement of low
computational complexities.

Switch point finding using polynomial regression for fuzzy type reduction algorithms

Karnik-Mendel (KM) algorithm is the most widely used type reduction (TR) method in literature for the design of interval type-2 fuzzy logic systems (IT2FLS). Its iterative nature for finding left and right switch points is its Achilles heel. Despite a decade of research, none of the alternative TR methods offer uncertainty measures equivalent to KM algorithm. This paper takes a data-driven approach to tackle the computational burden of this algorithm while keeping its key features. We propose a regression method to approximate left and right switch points found by KM algorithm. Approximator only uses the firing intervals, rnles centroids, and FLS strnctural features as inputs. Once training is done, it can precisely approximate the left and right switch points through basic vector multiplications. Comprehensive simulation results demonstrate that the approximation accuracy for a wide variety of FLSs is 100%. Flexibility, ease of implementation, and speed are other features of the proposed method.

Edgar Rice Burroughs' Martian Novels as an Early Paradigm of Racial Toleration

The Martian novels of Edgar Rice Burroughs (ERB) provide an early paradigm of racial toleration by displacing the heterogeneous race conflicts of the U. S. to an interplanetary location. There, the protagonist John Carter, representing Burroughs himself, introduces a level of racial acceptance and integration almost unheard of on the Earth of that era (the early twentieth century).

On Rememberance of Things Past: Woodstock and the Counterculture

The natural disposition of mankind is to want Utopia. In literature from the very beginning, from our most primitive to our most sophisticated verses, from the pens of atheists to acolytes, the human spirit has always scratched out, searched, even longed, for Utopias. When Utopias can somehow be linked to a political entity, the subsequent delirium from would-be followers numbers millions.

Harold Pinter, cinema e literatura : os limites da realidade

Partindo de duas questões teóricas preliminares, uma, da representação (literária e cinematográfica)do real e do imaginário, tanto no ângulo da produção como no da sua recepção e, a outra, da articulação entre formas de expressão artísticas distintas, ou seja, da interdisciplinaridade, este trabalho examina a presença do tema relativo aos limites entre realidade e fantasia no teatro, no cinema e na literatura, centrando sua atenção na obra de Harold Pinter. Consta de duas partes, cada uma com três capítulos. Na primeira, "Os pressupostos," discute-se as questões que fornecem seu substrato teórico. A segunda é dedicada ao corpus, identificando em seu título o tema investigado: "Os limites da realidade." Quanto à questão da representação, procura-se refutar "a afirmação de que a arte seja uma imitação da realidade. Uma releitura da Poética, de Aristóteles, reforçada pela opinião de diversos estudiosos da mesma, permite afirmar que a mÍmese corresponde, isto sim, a uma representação que envolve uma construção em que elementos da realidade são organizados segundo uma verdade criada pela própria obra, de acordo com critérios inerentes a ela. Além disso, através de uma leitura de Kathryn Hume, procura-se afirmar a interação sinestésica quase que permanente dos impulsos realista e da fantasiana literatura, identificando os tipos com que a fantasia se manifesta e as técnicas usadas para sua criação. A primeira parte encerra-se com um exame do relacionamento da literatura com as artes visuais e dramáticas, relações inter-disciplinares que situam este trabalho na literatura comparada.Dentre vários autores cujas obras contribuem para tal fim, destaca-se Martin Esslin, que estabelece os limitesde cada uma das artes dramáticas, identifica contatos delas com a literatura e permite, através de uma leitura de seu estudo sobre o teatro do absurdo, seja estabelecida a evolução que liga Aristóteles a Pinter. O corpus centra-se na obra de Pinterpara o teatro e para o cinema, sem limitar-se a ela,pois são também analisadas obras de outros escritores e cineastas, estabelendo-se aproximações ou contrastes entre elas. No quarto capítulo estão agrupadas obras nas quais desponta a imposição de verdades pela força fisica ou verbal. A luta pelo poder, a expulsão de elementos estranhos, dúvidas sobre a identidade e a inter-penetrablidade arte-vida caracterizam o capítulo seguinte. A ênfase temática do sexto capítulo recai sobre as limitações impostas pela condição humana. Praticamente todas as obras expressam a impossibilidade da existência de certezas absolutas e de uma perfeita distinção dos limites da realidade. Com isso, é possível afirmar não ser o objetivo da arte reproduzir a realidade. Mesmo que o fosse, tal tentativa resultaria infrutífera devido às limitações humanas.

Fatores de risco para óbito precoce em crianças e em adolescentes submetidos a tranplante hepático eletivo no Hospital de Clínicas de Porto Alegre

No próximo ano, completam-se 40 anos desde a primeira tentativa de transplante hepático (TxH) em seres humanos. Há quase 20 anos, o transplante (Tx) tornou-se uma opção terapêutica real para os pacientes portadores de doença hepática terminal. Atualmente, o TxH é o tratamento de escolha para diversas enfermidades hepáticas, agudas ou crônicas. Dos transplantes realizados na Europa ou nos EUA, em torno de 12% dos pacientes são crianças e adolescentes. No Brasil, 20,9% dos pacientes transplantados de fígado em 2001 tinham até 18 anos de idade e, destes, 60,7% tinham 5 anos ou menos. O objetivo do TxH é a manutenção da vida dos pacientes com doença hepática irreversível, e a principal forma de avaliação de sucesso é a sobrevida após o Tx. A primeira semana que se segue ao TxH, apesar dos excelentes progressos dos últimos anos, continua sendo o período mais crítico. A maioria dos óbitos ou das perdas do enxerto ocorrem nas primeiras semanas, em particular, nos primeiros 7 dias de TxH. Diversos fatores de risco para o resultado do TxH podem ser identificados na literatura, porém há poucos estudos específicos do Tx pediátrico. As crianças pequenas apresentam características particulares que os diferenciam do Tx nos adultos e nas crianças maiores. Com o objetivo de identificar fatores de risco para o óbito nos 7 primeiros dias após os transplantes hepáticos eletivos realizados em 45 crianças e adolescentes no Hospital de Clínicas de Porto Alegre entre março de 1995 e agosto de 2001, foi realizado um estudo de caso-controle. Entre os 6 casos (13,3%) e os 39 controles foram comparadas características relacionadas ao receptor, ao doador e ao procedimento cirúrgico e modelos prognósticos. Das variáveis relacionadas ao receptor, o gênero, o escore Z do peso e da estatura para a idade, a atresia de vias biliares, a cirurgia abdominal prévia, a cirurgia de Kasai, a história de ascite, de peritonite bacteriana espontânea, de hemorragia digestiva e de síndrome hepatopulmonar, a albuminemia, o INR, o tempo de tromboplastina parcial ativada e o fator V não foram associados com o óbito na primeira semana. A mortalidade inicial foi maior nas crianças com menor idade (p=0,0035), peso (p=0,0062) e estatura (p<0,0001), bilirrubinemia total (BT) (p=0,0083) e bilirrubinemia não conjugada (BNC) (p=0,0024) elevadas, e colesterolemia reduzida (p=0,0385). Os receptores menores de 3 anos tiveram um risco 25,5 vezes maior de óbito que as crianças maiores (IC 95%: 1,3–487,7). A chance de óbito após o Tx dos pacientes com BT superior a 20 mg/dL e BNC maior que 6 mg/dL foi 7,8 (IC95%: 1,2–50,1) e 12,7 (IC95%: 1,3–121,7) vezes maior que daqueles com níveis inferiores, respectivamente. Das características relacionadas ao doador e ao Tx, as variáveis gênero, doador de gênero e grupo sangüíneo ABO não idênticos ao do receptor, razão peso do doador/receptor, causa do óbito do doador, enxerto reduzido, tempo em lista de espera e experiência do Programa não foram associados com o óbito nos primeiros 7 dias. Transplantes com enxertos de doadores de idade até 3 anos, ou de peso até 12 Kg representaram risco para o óbito dos receptores 6,8 (IC95%: 1,1–43,5) e 19,3 (IC95%: 1,3–281,6) vezes maior, respectivamente. O tempo de isquemia total foi em média de 2 horas maior nos transplantes dos receptores não sobreviventes (p=0,0316). Os modelos prognósticos Child-Pugh, Rodeck e UNOS não foram preditivos do óbito. Os pacientes classificados como alto risco no modelo de Malatack apresentaram razão de chances para o óbito 18,0 (IC95%: 1,2–262,7) vezes maior que aqueles com baixo risco. A mortalidade na primeira semana foi associada a valores elevados do escore PELD. O risco de óbito foi de 11,3 (IC95%: 1,2–107,0) nas crianças com valor do PELD maior que 10. As crianças pequenas e com maior disfunção hepática apresentaram maior risco de óbito precoce. Doador de pequeno porte e prolongamento do tempo de isquemia também foram associados à mortalidade. Somente os modelos de Malatack e PELD foram preditivos da sobrevida.