Reconstruction of metal pollution and recent sedimentation processes in Havana Bay (Cuba): A tool for coastal ecosystem management.

Since 1998 the highly polluted Havana Bay ecosystem has been the subject of a mitigation program. In order to determine whether pollution-reduction strategies were effective, we have evaluated the historical trends of pollution recorded in sediments of the Bay. A sediment core was dated radiometrically using natural and artificial fallout radionuclides. An irregularity in the (210)Pb record was caused by an episode of accelerated sedimentation. This episode was dated to occur in 1982, a year coincident with the heaviest rains reported in Havana over the XX century. Peaks of mass accumulation rates (MAR) were associated with hurricanes and intensive rains. In the past 60 years, these maxima are related to strong El Niño periods, which are known to increase rainfall in the north Caribbean region. We observed a steady increase of pollution (mainly Pb, Zn, Sn, and Hg) since the beginning of the century to the mid 90s, with enrichment factors as high as 6. MAR and pollution decreased rapidly after the mid 90s, although some trace metal levels remain high. This reduction was due to the integrated coastal zone management program introduced in the late 90s, which dismissed catchment erosion and pollution.

Department of Commerce - Division of Banking Performance Plan, FY 2009

Agency Performance Plan, Department of Commerce - Division of Banking

Department of Human Rights – Division of Central Administration Performance Plan, FY 2009

Agency Performance Plan, Department of Human Rights – Division of Central Administration

Division of Criminal and Juvenile Justice Planning, Department of Human Rights Performance Plan, FY 2009

Agency Performance Plan, Division of Criminal and Juvenile Justice Planning, Department of Human Rights

Department of Human Rights, Division of Community Action Agencies Performance Plan, FY 2009

Agency Performance Plan, Department of Human Rights, Division of Community Action Agencies

Division of Persons with Disabilities Performance Plan, FY 2009

Agency Performance Plan, Division of Persons with Disabilities

Department of Human Rights Division of Latino Affairs, FY 2009

Agency Performance Plan, Department of Human Rights Division of Latino Affairs

Iowa Division of Criminal and Juvenile Justice Planning, Strategic Plan, 2007

This report outlines the strategic plan for Iowa Division of Criminal and Juvenile Justice Planning including,goals and mission.

Iowa Division of Community Action Agencies, Strategic Plan, 2003

This report outlines the strategic plan for Iowa Division of Community Action Agenciesg including,goals and mission.

Iowa Division of Latino Affairs, Strategic Plan, 2003

This report outlines the strategic plan for Iowa Division of Latino Affairs including, goals and mission.

Iowa Division of Persons with Disabilities, Strategic Plan, 2003

This report outlines the strategic plan for Iowa Division of Persons with Disabilities, goals and mission.

Audit report on the Iowa Federal Family Education Loan Program Division, a Division of the Iowa College Student Aid Commission, for the year ended June 30, 2008

Audit report on the Iowa Federal Family Education Loan Program Division, a Division of the Iowa College Student Aid Commission, for the year ended June 30, 2008

The major genetic determinants of HIV-1 control affect HLA class I peptide presentation.

Infectious and inflammatory diseases have repeatedly shown strong genetic associations within the major histocompatibility complex (MHC); however, the basis for these associations remains elusive. To define host genetic effects on the outcome of a chronic viral infection, we performed genome-wide association analysis in a multiethnic cohort of HIV-1 controllers and progressors, and we analyzed the effects of individual amino acids within the classical human leukocyte antigen (HLA) proteins. We identified >300 genome-wide significant single-nucleotide polymorphisms (SNPs) within the MHC and none elsewhere. Specific amino acids in the HLA-B peptide binding groove, as well as an independent HLA-C effect, explain the SNP associations and reconcile both protective and risk HLA alleles. These results implicate the nature of the HLA-viral peptide interaction as the major factor modulating durable control of HIV infection.