967 resultados para Howell (Mich.)


Relevância:

10.00% 10.00%

Publicador:

Resumo:

Die Tanzwissenschaft sieht sich stets mit methodischen Herausforderungen und mit der Schwierigkeit konfrontiert Tanzereignisse in eine diskursive Form zu bringen. Es gilt, singuläre und adäquate – oft interdisziplinäre – Methoden für den jeweiligen Untersuchungsgegenstand zu finden. In meinem Beitrag möchte ich danach fragen, inwiefern sich eine jeweilige Methode aus dem konkreten Untersuchungsgegenstand heraus ergeben kann. Exemplarisch beschäftige ich mich mit der ‚improvisierten Choreographie’ Accords von Thomas Hauert und der Kompanie ZOO. Das choreographische Prinzip in Accords ist das improvisierte Unisono. Die Tanzenden orientieren sich aneinander, übernehmen Bewegungen voneinander und agieren vergleichbar einem Vogel- oder Fischschwarm. Mittels der Denkfigur des Schwarms möchte ich diese so entstehenden ‚schwärmenden Konstellationen’ beschreiben und die Funktions- und Operationsregeln dieses Gebildes analysieren. Des Weiteren sollen mit dieser epistemologischen Figur die kinästhetischen Übertragungsprozesse diskutiert werden, die sich zwischen den Tanzenden ereignen. Die Schwarmfigur scheint geradezu prädestiniert für die Betrachtung einer Tanzimprovisation. Beide Phänomene – der Schwarm und die Improvisation gleichermassen – zeichnen sich aus durch Transitorik, Performativität, Kontingenz und Emergenz. Dennoch gilt es nicht nur nach dem Potenzial eines solchen Vorgehens und der Produktivität dieser epistemologischen Denkfigur zu fragen, sondern auch mögliche Schwierigkeiten zu problematisieren.

Relevância:

10.00% 10.00%

Publicador:

Resumo:

Myosin B (MyoB) is one of the two short class XIV myosins encoded in the Plasmodium genome. Class XIV myosins are characterized by a catalytic "head," a modified "neck," and the absence of a "tail" region. Myosin A (MyoA), the other class XIV myosin in Plasmodium, has been established as a component of the glideosome complex important in motility and cell invasion, but MyoB is not well characterized. We analyzed the properties of MyoB using three parasite species as follows: Plasmodium falciparum, Plasmodium berghei, and Plasmodium knowlesi. MyoB is expressed in all invasive stages (merozoites, ookinetes, and sporozoites) of the life cycle, and the protein is found in a discrete apical location in these polarized cells. In P. falciparum, MyoB is synthesized very late in schizogony/merogony, and its location in merozoites is distinct from, and anterior to, that of a range of known proteins present in the rhoptries, rhoptry neck or micronemes. Unlike MyoA, MyoB is not associated with glideosome complex proteins, including the MyoA light chain, myosin A tail domain-interacting protein (MTIP). A unique MyoB light chain (MLC-B) was identified that contains a calmodulin-like domain at the C terminus and an extended N-terminal region. MLC-B localizes to the same extreme apical pole in the cell as MyoB, and the two proteins form a complex. We propose that MLC-B is a MyoB-specific light chain, and for the short class XIV myosins that lack a tail region, the atypical myosin light chains may fulfill that role.

Relevância:

10.00% 10.00%

Publicador:

Resumo:

Mit Kuno verbindet mich nicht allein das lnteresse an einer Theorie der Religion (Füssel, Huber, & Walpen, 1990). Mit dieser allerdings habe ich mich in den letztenJahren am intensivsten auseinandergesetzt. Daher erscheint es mir sinnvoll, zu dieser Thematik meinen Beitrag zu seiner Festschrift zu leisten. Kurzgefasst geht es darin um prosoziale Effekte religiôser Konstruktsysteme. Es lasst sich namlich zeigen, dass sie einen ideologischen Mechanismus zu neutralisieren vermôgen, wenn sie einen determinierenden Einfluss auf das Verhalten ausüben. Dabei spielt der Glaube, der nach einem allseits bekannten Diktum sogar Berge versetzen kann, eine entscheidende Rolle. Daher lese ich in dem Oberthema der Festschrift einen «Genitivus subjectivus». Es lautet dann: Suchet zuerst die Gerechtigkeit, die Gott realisiert bzw. realisieren wird. lch beginne mit der Darstellung einer sozialpsychologischen Theorie, die zu erklaren versucht, warum Menschen, die von einem ungerechten Ereignis getroffen werden, zu allem Überfluss auch noch die Schuld daran in die Schuhe geschoben bekommen. ln einem zweiten Schritt definiere ich, was ich unter religiôsen Konstruktsystemen verstehe und wie sie in sozialwissenschaftlichen Studien gemessen werden kônnen. Darauf aufbauend versuche ich zu prazisieren, wie religiôse Konstruktsysteme den Mechanismus der Schuldzuschreibung beeinflussen. Dazu greife ich aufDaten zurück, die ich 1999 in einer eigenen Untersuchung mit einer reprasentativen Stichprobe von Studierenden der Universitat Freiburg im Uechtland erhoben habe.

Relevância:

10.00% 10.00%

Publicador:

Resumo:

The aim of this study was to analyse the osseointegrative potential of phosphoserine-tethered dendrons when applied as surface functionalisation molecules on titanium implants in a sheep model after 2 and 8 weeks of implantation. Uncoated and dendron-coated implants were implanted in six sheep. Sandblasted and etched (SE) or porous additive manufactured (AM) implants with and without additional dendron functionalisation (SE-PSD; AM-PSD) were placed in the pelvic bone. Three implants per group were examined histologically and six implants were tested biomechanically. After 2 and 8 weeks the bone-to-implant contact (BIC) total values of SE implants (43.7 ± 12.2; 53.3 ± 9.0 %) and SE-PSD (46.7 ± 4.5; 61.7 ± 4.9 %) as well as AM implants (20.49 ± 5.1; 43.9 ± 9.7 %) and AM-PSD implants (19.7 ± 3.5; 48.3 ± 15.6 %) showed no statistically significant differences. For SE-PSD and AM-PSD a separate analysis of only the cancellous BIC demonstrated a statistically significant difference after 2 and 8 weeks. Biomechanical findings proved the overall increased stability of the porous implants after 8 weeks. Overall, the great effect of implant macro design on osseointegration was further supported by additional phosphoserine-tethered dendrons for SE and AM implants.

Relevância:

10.00% 10.00%

Publicador:

Resumo:

Welsch (Projektbearbeiter): Sarkastische Kommentierung der Aktivitäten der sogenannten Volksredner: "... [Es] schmerzt ... mich, daß jetzt jeder Straßenbube Staatsmännchen spielen möchte und zu demokräteln sucht. Jeder ..., der Freiheit ... aufrichtig will, ... wird ... sich mit Verachtung von einem Treiben abwenden, welches das Wort 'Demokratie' ganz in Verruf zu bringen droht." Unter einem Pseudonym verfaßt von dem sich als 'entschieden freisinnig' bezeichnenden Buchhändler und Schriftsteller Adolf Gumprecht

Relevância:

10.00% 10.00%

Publicador:

Relevância:

10.00% 10.00%

Publicador:

Resumo:

Welsch (Projektbearbeiter): Polemik gegen den von Friedrich Daniel Bassermann, Unterstaatssekretär im Reichsministerium des Innern, der Frankfurter Nationalversammlung am 18. November 1848 erstatteten Bericht über die Lage in Berlin. Aufsehen und Anstoß erregte vor allem folgender Satz: "... ich ... muß gestehen, daß mich die Bevölkerung, welche ich auf [den Straßen] ... erblickte, erschreckte. Ich sah hier Gestalten die Straßen bevölkern, die ich nicht schildern will." (die sprichwörtlich gewordenen 'Bassermannschen Gestalten'). Unterzeichnet von 83 Personen, darunter zahlreichen Abgeordneten der Preußischen Nationalversammlung

Relevância:

10.00% 10.00%

Publicador:

Resumo:

Welsch (Projektbearbeiter): Aufruf des Militärgouverneurs Welden an die "rechtlichen und verständigen Bewohner Wiens" zur Unterstützung seiner Politik der Wiederherstellung von "Ordnung und Gesetz". "Ihr werdet die Stimme der Vernunft ... erkennen, und mich nicht zwingen, im Donner der Geschütze die Ordnung zu verkünden."

Relevância:

10.00% 10.00%

Publicador:

Resumo:

Small, cool planets represent the typical end-products of planetary formation. Studying the architectures of these systems, measuring planet masses and radii, and observing these planets' atmospheres during transit directly informs theories of planet assembly, migration, and evolution. Here we report the discovery of three small planets orbiting a bright (K-s = 8.6 mag) M0 dwarf using data collected as part of K2, the new ecliptic survey using the repurposed Kepler spacecraft. Stellar spectroscopy and K2 photometry indicate that the system hosts three transiting planets with radii 1.5-2.1 R-circle plus, straddling the transition region between rocky and increasingly volatile-dominated compositions. With orbital periods of 10-45 days the planets receive just 1.5-10x the flux incident on Earth, making these some of the coolest small planets known orbiting a nearby star; planet d is located near the inner edge of the system's habitable zone. The bright, low-mass star makes this system an excellent laboratory to determine the planets' masses via Doppler spectroscopy and to constrain their atmospheric compositions via transit spectroscopy. This discovery demonstrates the ability of K2 and future space-based transit searches to find many fascinating objects of interest.

Relevância:

10.00% 10.00%

Publicador:

Resumo:

T-cell lymphomas from AKR mice were studied to determine their potential as a model of T-cell differentiation. Homogeneous tumor cell lines have been used as model to study normal lymphocyte subpopulations, including differentiation lineages, functional properties, and the inducibility to maturation. The underlying concept is that each lymphoid tumor represents a monoclonal neoplastic proliferation of a discrete lymphoid subpopulation arrested at a particular differentiation stage.^ Individual tumors were analyzed to determine the extent of intertumor heterogeneity, and to determine whether lymphomas represented different thymocyte subsets, by determining the cell-surface antigenic phenotype, PNA-binding capacity, and terminal deoxynucleotidyl transferase (TdT) activity. Splenic and thymic tumor cells were compared to determine if the particular lymphoid microenvironment influenced T-cell marker expression. Several of the lymphomas were passaged in syngeneic hosts to verify the original tumor phenotype and to assess the stability of the cell surface and TdT phenotype after transplantation.^ Lymphomas were adapted to in vitro culture to determine whether the T-cell phenotype was maintained in the absence of the host microenvironment. Clonal progeny were analyzed and compared with each other and with parent cell lines to determine the extent of intratumor heterogeneity in this lymphoma system. Parent and cloned cell lines were passaged in vivo to determine whether alterations in surface phenotype occurred after transplantation.^ Our investigation has verified that most spontaneous AKR lymphomas phenotypically resemble known T-cell subsets, including both immature and mature thymic subpopulations. The in vitro lines, however, expressed a highly unstable phenotype in culture that included loss of Ly-1 and Ly-2 antigen expression. After transplantation in vivo, the in vitro lines exhibited alterations in phenotype, including re-expression of Ly antigen on some lymphomas. The inducibility of T-cell antigen markers on tumor cell lines passaged in vivo suggests that the in vitro lines may serve as a possible model system to study the molecular events involved in gene expression in the T-cell system. ^

Relevância:

10.00% 10.00%

Publicador:

Resumo:

[Georg Philipp Telemann]

Relevância:

10.00% 10.00%

Publicador:

Resumo:

lass mich Dir blüh'n

Relevância:

10.00% 10.00%

Publicador:

Resumo:

The study of obesity and its causes has evolved into one of the most important public health issues in the United States (Office of Disease Prevention and Health Promotion, 2007). Obesity is linked to several chronic conditions, such as cardiovascular disease, diabetes and some cancers (National Center for Chronic Disease Prevention and Health Promotion, 2008b) and the public health concern resides in the present morbidity and mortality associated with obesity and related conditions (National Heart, Lung and Blood Institute, 1998). Furthermore, obesity and its related conditions present economic challenges to employers in terms of medical health care, sick leave, short-term disability and long-term disability benefits utilized by employees (Østbye, Dement, and Krause, 2007). Recently, articles covering intervention programs targeting obesity in the occupational setting have surfaced in the body of scientific literature. The increased interest in this area stems from the fact that employees in the United States spend more time in the work environment than many industrialized nations, including Japan and most of Western Europe (Organisation for Economic Co-operation and Development, 2006). Moreover, scientific literature supports the idea of investing in healthy human capital to promote productivity and output from employees (Berger, Howell, Nicholson, & Sharda, 2003). The time spent in the work environment, the business need for healthy employees, and the public health concern create an opportunity for planning, implementation and analysis of interventions for effectiveness. This paper aims to identify those intervention programs that focus on the occupational setting related to obesity, to analyze the overall effect of diet, physical fitness and behavioral change interventions targeting overweight and obesity in the occupational setting, and to evaluate the details and effectiveness of components, such as, intervention setting, target participant group, content, industry and length of follow up. Once strengths and weaknesses of the interventions are evaluated, ideas will be suggested for implementation in the future.^