Hipertensão arterial e cuidados com a saúde: concepções de homens e mulheres

Pós-graduação em Psicologia do Desenvolvimento e Aprendizagem - FC

Crimes em comum: escravidão e liberdade sob a pena do Estado imperial brasileiro (1830-1888)

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Genealogia de uma operação historiográfica: as apropriações dos pensamentos de Edward Palmer Thompson e de Michel Foucault pelos historiadores brasileiros na década de 1980

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

O perfil da sexualidade em homens com lesão medular

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

O gênero masculino e os cuidados de saúde: a experiência de homens de um centro de saúde

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Padrões de busca e uso de artigos científicos: um estudo com pós-graduandos em educação brasileiros

This article presents part of a larger study on the use of reference sources to perform bibliographical search by graduate students in Education. Data relating to the use of the scientific journals by these students are presented and discussed. Sixty Education graduate students, 28 Master degree and 32 Doctoral, answered an electronic questionnaire. The students indicated the types of articles usually read and the importance attributed to each one. For each of treated themes in the electronic questionnaire, data are initially presented and analyzed in the set of the 60 participants of the study and then compared between master and doctoral students. Were used the Chi-squared (?2) test, the Fisher exact test and the Spearman’s correlation coefficient. Research reports were more frequently pointed out but less valued in comparison to articles referring to critical review and theoretical essay. Methodological articles, appearing in fourth position according to reading frequency and importance attributed, are more valued by doctoral than master students. The students read these articles using different procedures. The possible reasons for the students valorizing the articles of critical review and theoretical essays are discussed. The present study intends to offer a contribution to understand the use of scientific information by students, describing some graduate students’ habits related to information seeking in scientific journals, and reading of the articles published.

Mapeamento da situação educacional dos alunos surdos de munícipios brasileiros atendidos pelo curso de língua brasileira de sinais na modalidade à distância

Recent years have seen a movement toward school inclusion of children with special educational needs. In Brazil, there is the formulation of laws guaranteeing rights for disabled people, giving you free access to regular classroom complemented by specialized educational services. In the case of students with deafness, the Federal Decree No. 5626 of 2005, recommends that schools offer the Brazilian sign language as language support, and should take into classrooms, an interpreter. In this study we conducted a mapping of the educational situation of students with hearing loss of 35 municipalities. There was a mode of education in which deaf students are enrolled, and also the municipalities have organized the specialized educational services for such students. Data were collected through interviews with managers of 35 municipalities. The results showed that the vast majority of municipalities participating in the study opted for the enrollment of deaf students in regular class. Only a few municipalities managers reported the existence of classes and enrollment in special schools or even the existence of deaf students out of schools. It also found that all municipalities have organized the specialized educational services, like additional offering in the resource rooms. We conclude that despite the existing difficulties, the Brazilian municipalities are gradually adjusting to the prospect of inclusive education. Continuing education courses should be offered in order to prepare more teachers to work with diversity.

Atitudes sociais em relação à inclusão: estudos brasileiros

An important component of the Inclusive Education can be the social attitudes toward inclusion presented by teachers, students and other members of the school community. The aim of this paper is to systematize main fidings of some Brazilian studies concerning that theme. The results of studies in which the Likert Scale of Social Attitudes toward Inclusion was used are summarized. Twelve studies were analyzed, examining the relationship between the social attitudes toward inclusion and some subjects characteristics, highlighting the chronological age, formation area, educational experience and previous experience with people with deficiency. The results were not able to demonstrate in a conclusive way the nature of the relationship between each of these variables and the social attitudes toward inclusion. These seem to be affected by a group of complexly related variables of the subjects and of the target of social attitudes.

Profissionais mediadores da informação: experiências didático pedagógicas em dois cursos de biblioteconomia brasileiros

The context political, social and economical determines the material conditions of the individual's cultural formation and it influences in the constitution of the critical conscience and social responsibility. The aim of this paper is to describe the didactic experiences from discussions in classroom with students in disciplines dedicated to information access in the Brazilian librarianship courses from São Paulo State University (Unesp), state of São Paulo, and Federal University of Alagoas (UFAL), state of Alagoas, precisely: Information Dissemination, supplied in 2007 and 2010, and Information Dissemination and Sources, supplied in 2008 and 2009, besides Library and Cultural Action, accomplished of 2008 to 2009. It was noticed, starting from the experience in classroom, that the Librarianship students have low knowledge of the institutions librarians and their services; they told that not to know the main library services before they study them referred disciplines.

Não aprender na visão de crianças e adolescentes brasileiros: um estudo evolutivo na perspectiva piagetiana

This article aims to present dada from a research about the construction of social knowledge under the Piagetian perspective. Beliefs of children and adolescents about not to learn were investigated. 80 individuals aged 6 to 16 years participated of this study. They had to answer to three methodological tools: a drawing, the analysis of a history and the analysis of a film which involved situations of not learning. It will be presented here the main results of the drawing task. Among other results, data indicate that a significant part of the participants blame the students themselves for not learning, by factors such as indiscipline and lack of motivation. Results also show that Brazilian individuals are not in advanced levels of understanding of social reality, even at older ages.

Uma proposta linguística para o ensino da escrita formal para surdos brasileiros e portugueses

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Structural characterization of diastereoisomeric ethano adducts derived from the reaction of 2'-deoxyguanosine with trans,trans-2,4-decadienal

Background levels of exocyclic DNA adducts have been detected in rodent and human tissues. Several studies have focused on bifunctional electrophiles generated from lipid peroxidation as one of the endogenous sources of these lesions. We have previously shown that the reaction of 2'-deoxyguanosine (dGuo) with trans,trans-2,4-decadienal (DDE), a highly cytotoxic aldehyde generated as a product of lipid peroxidation in cell membranes, results in the formation of a number of different base derivatives. Three of these derivatives have been fully characterized as 1,N-2-etheno-2'-deoxyguanosine adducts. In the present work, four additional adducts, designated A3-A6, were isolated from in vitro reactions by reversed-phase HPLC and fully characterized on the basis of spectroscopic measurements. Adducts A3-A6 are four diastereoisomeric 1,N-2-hydroxyethano-2'-deoxyguanosine derivatives possessing a carbon side chain with a double bond and a hydroxyl group. The systematic name of these adducts is 6-hydroxy3-(2'-deoxy-beta-D-erythro-pentafuranosyl)-7-((E)-1-hydroxy-oct-2-enyl)-3,5,6,7-tetrahydro-imidazo- [1,2-a]purin-9-one. The proposed reaction mechanism yielding adducts A3-A6 involves DDE epoxidation at C2, followed by nucleophilic addition of the exocyclic amino group of dGuo to the C1 of the aldehyde and cyclization, via nucleophilic attack, on the C2 epoxy group by N-1. The formation of adducts A1-A6 has been investigated in acidic, neutral, and basic pH in the presence of H2O2 or tent-butyl hydroperoxide. Neutral conditions, in the presence of H2O2, have favored the formation of adducts A1 and A2, with minor amounts of A3-A6, which were prevalent under basic conditions. These data indicate that DDE can modify DNA bases through different oxidative pathways involving its two double bonds. It is important to structurally characterize DNA base derivatives induced by alpha,beta-unsaturated aldehydes so that the genotoxic risks associated with the lipid peroxidation process can be assessed.

Formation of 1,N-6-etheno-2 '-deoxyadenosine adducts by trans,trans-2,4-decadienal

trans,trans-2,4-Decadienal (DDE) is an important breakdown product of lipid peroxidation. This aldehyde is cytotoxic to mammalian cells and is known to be implicated in DNA damage. Therefore, attempts were made in this work to assess the reactivity of DDE with 2'-deoxyadenosine (dAdo). It was shown that DDE is able to bind to 2'-deoxyadenosine, yielding highly fluorescent products. Besides 1,N-6-etheno-2'-deoxyadenosine (epsilon dAdo), two other related adducts, 1-[3-(2-deoxy-beta-D-erythro-pentofuranosyl)3H-imidazo[2,1-i]purin-7-yl]-1,2,3-octanetriol and 1-[3-(2-deoxy-beta-D-erythro-pentofuranosyl)-3H-imidazo[2,1-i]purin-7-yl]-1,2-heptanediol, were isolated by reverse phase high-performance liquid chromatography and characterized on the basis of their UV, fluorescence, nuclear magnetic resonance, and mass spectrometry features. The reaction mechanism for the formation of the DDE-2'-deoxyadenosine adducts involves 2,4-decadienal epoxidation and subsequent addition to the N-2 amino group of 2'-deoxyadenosine, followed by cyclization at the N-1 site. Adducts differ by the length of carbon side chain and the number of hydroxyl groups. The present data indicate that DDE can be epoxidized by peroxides, and the resulting products are able to form several adducts with 2'-deoxyadenosine and/or DNA. Endogenous DNA adduct formation can contribute to the already reported high cytotoxicity of DDE to mammalian cells.