979 resultados para HELICAL CT
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Vol. 15, 560 p., without t.p. or index. In the L.C. copy, only the first number has cover title
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"Extracted from the appendix (VI) to Mr. E. Baldwin's History of Yale College."-- T.p.
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"February 1971."
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Includes index.
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Includes index.
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"August 1991."
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Each issue has a distinctive title.
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Law.--La Chine.--L'Empire russe depuis le Congrès de Vienne.--Tallemant des Réaux.--La société française pendant la révolution.--L'Empire chinois.--Le Sahara algérien et le Grand désert.--Les Kœnigsmark.--L'ancien régime et la révolution.--Le christianisme en Chine, en Tartarie et au Thibet.--L'insurrection normande en 1793.--Les Philippiques de La Grange-Chancel.--Louis XVI et sa cour.--Gabrielle d'Estrées et Henry IV.--Mathilde de Toscane.--Joseph de Maistre.--Royalistes et républicains.--Les civilisations.--La diplomatie au XVIIe siècle.--Deux diplomates [Le comte Raczynski et Donoso Cortès]--Saint-Simon.--Le marquis de Grignan.--Philippe II.
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Mode of access: Internet.
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Trägerband: Ms. Barth. 66; Vorbesitzer: St. Peter Urach; Bartholomaeusstift Frankfurt am Main
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Tau is a major microtubule-associated protein of axons and is also the principal component of the paired helical filaments (PHFs) that comprise the neurofibrillary tangles found in Alzheimer's disease and other tauopathies. Besides phosphorylation of tau on serine and threonine residues in both normal tau and tau from neurofibrillary tangles, Tyr-18 was reported to be a site of phosphorylation by the Src-family kinase Fyn. We examined whether tyrosine residues other than Tyr-18 are phosphorylated in tau and whether other tyrosine kinases might phosphorylate tau. Using mass spectrometry, we positively identified phosphorylated Tyr-394 in PHF-tau from an Alzheimer brain and in human fetal brain tau. When wild-type human tau was transfected into fibroblasts or neuroblastoma cells, treatment with pervanadate caused tau to become phosphorylated on tyrosine by endogenous kinases. By replacing each of the five tyrosines in tau with phenylalanine, we identified Tyr-394 as the major site of tyrosine phosphorylation in tau. Tyrosine phosphorylation of tau was inhibited by PP2 (4-amino-5-(4-chlorophenyl-7-(t-butyl) pyrazolo[3,4-d] pyrimidine), which is known to inhibit Src-family kinases and c-Abl. Cotransfection of tau and kinases showed that Tyr-18 was the major site for Fyn phosphorylation, but Tyr-394 was the main residue for Abl. In vitro, Abl phosphorylated tau directly. Abl could be coprecipitated with tau and was present in pretangle neurons in brain sections from Alzheimer cases. These results show that phosphorylation of tau on Tyr-394 is a physiological event that is potentially part of a signal relay and suggest that Abl could have a pathogenic role in Alzheimer's disease.
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A practical, small-size, dual-helical antenna array mounted on a mobile handset model is designed for use as diversity/MIMO receiving antennas. The array is rigorously studied with respect to its diversity performance and the achievable channel capacity. It is found that a very low correlation coefficient, a high diversity gain, an equal-mean branch SNR, and a relatively matched input impedance can be achieved at the same time. It is shown that, at a remarkably small antenna separation (similar to 0.05 lambda), the signal correlation can be reduced to nearly zero, an almost ideal independent operation of the diversity antennas. The increase in MIMO channel capacity is 100% over a single antenna system. Both measured and simulation results are presented.
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This comment points out an inaccurate formula relating the signal correlation coefficient to the mutual impedance and corrects it. © 2005 IEEE.