Gedächtnisrede zu Ehren des verewigten Vorsitzenden der Gesellschaft zur Förderung der Wissenschaft des Judentums, des Prof. Dr. Martin Philippson, gehalten in d. Mitgliederversammlung zu Berlin am 27 Dez. 1916

von Philipp Bloch

Sir Moses Montefiore : ein Lebensbild f. jung u. alt

von Eugen Wolbe. Hrsg. unter Mitw. der Jugenschriften-Kommission der Großloge für Deutschland VIII U.O.B.B.

Ein moderner Methusalem : Bemerkungen u. Betrachtungen anlässl. d. denkwürd. Testaments des Baronets Sir Moses Montefiore, sowie Anekdoten, Memoiren ... dieses grossen Philantropen

zusgest. von Moritz Tuschak

Compte rendu des fêtes ceĺebreés a Ramsgate en l'honneur du 99e anniversaire de Sir Moses Montefiore : 8. Heshvan 5644 - 8. Nov. 1883

trad. de l'anglais par Mme P. Pereyra, née Bloch

Translations of a letter addressed by Sir Moses Montefiore to the Jewish Congregations in the Holy Land, on the promotion of agriculture and other industrial pursuits in that country and of the replies received thereto

London Comm. of Deputies of the Brit. Jews

Martin Buber : Werke über das Judentum

[Verf.: Gustav Landauer]

An open letter addressed to Sir Moses Montefiore ... on the day of his arrival in the holy city of Jerusalem

by Meyer Auerbach and Samuel Salant

Sir Moses Montefiore Bart. F. R. S. : ein Lebensbild ; zum Andenken seines hundertsten Lebensjahres ...

aus dem Englischen des Israel Davis in's Deutsche übersetzt von Josef Fiebermann

Sir Moses Montefiore Bart. F. R. S. : ein Lebensbild ; zum Andenken seines hundertsten Lebensjahres ...

aus dem Englischen des Israel Davis in's Deutsche übersetzt von Josef Fiebermann

Diaries of Sir Moses and Lady (Judith) Montefiore : comprising their life and work as recorded in their diaries from 1812 to 1883

ed. by L. Loewe

Development of small molecular tools for the cellular study of adenosine receptors

The adenosine receptors are members of the G-protein coupled receptor (GPCR) family which represents the largest class of cell-surface proteins mediating cellular communication. As a result, GPCRs are formidable drug targets and it is estimated that approximately 30% of the marketed drugs act through members of this receptor class. There are four known subtypes of adenosine receptors: A1, A2A, A2B and A3. The adenosine A1 receptor, which is the subject of this presentation, mediates the physiological effects of adenosine in various tissues including the brain, heart, kidney and adipocytes. In the brain for instance, its role in epilepsy and ischemia has been the focus of many studies. Previous attempts to study the biosynthesis, trafficking and agonist-induced internalisation of the adenosine A1 receptor in neurons using fluorescent protein-receptor fusion constructs have been hampered by the sheer size of the fluorescent protein (GFP) that ultimately affected the function of the receptor. We have therefore initiated a research programme to develop small molecule fluorescent agonists that selectively activate the adenosine A1 receptor. Our probe design is based on the endogenous ligand adenosine and the known unselective adenosine receptor agonist NECA. We have synthesised a small library of non-fluorescent adenosine derivatives that have different cyclic and bicyclic moieties at the 6 position of the purine ring and have evaluated the pharmacology of these compounds using a yeast-based assay. This analysis revealed compounds with interesting behaviour, i.e. exhibiting subtype-selectivity and biased signalling, that can be potentially used as tool compounds in their own right for cellular studies of the adenosine A1 receptor. Furthermore, we have also linked fluorescent dyes to the purine ring and discovered fluorescent compounds that can activate the adenosine A1 receptor.