Design principles for an enterprise systems chartering method

Our research follows a design science approach to develop a method that supports the initialization of ES implementation projects – the chartering phase. This project phase is highly relevant for implementation success, but is understudied in IS research. In this paper, we derive design principles for a chartering method based on a systematic review of ES implementation literature and semi-structured expert interviews. Our analysis identifies differences in the importance of certain success factors depending on the system type. The proposed design principles are built on these factors and are linked to chartering key activities. We specifically consider system-type-specific chartering aspects for process-centric Business Intelligence & Analytics (BI&A) systems, which are an emerging class of systems at the intersection of BI&A and business process management. In summary, this paper proposes design principles for a chartering method – considering specifics of process-centric BI&A.

Ontological representation of design science research publications

A search result provided by existing digital library and web search systems typically comprises only a prioritised list of possible publications or web pages that meet the search criteria, possibly with excerpts and possibly with search terms highlighted. The research in progress reported in this poster contributes to a larger research effort to provide a readable summary of search results that synthesise relevant publications or web pages to provide results that meet four C’s: comprehensive, concise, coherent, and correct, as a more useful alternative to un-synthesised result lists. The scope of this research is limited to searching for and synthesising Design Science Research (DSR) publications that present the results of DSR, as an example problem domain.

Achieving continuous professional development in higher education

Traditional higher education technology emphasizes knowledge transmission. In contrast, the Community platform presented in this paper follows a social approach that interleaves knowledge delivery with social and professional skills development, engaging with others, and personal growth. In this paper, we apply learning and complex adaptive systems theory to motivate and justify a continuous professional development model that improves higher education outcomes such as placement. The paper follows action design research (ADR) as the research method to propose and evaluate design principles.

A support system for mentors of novice entrepreneurs

In this study we present online software to rapidly assess the impact of mentoring techniques on a novice entrepreneur. We have built a prototype that collects data from team members in less than five minutes and that automatically returns a diagnostic analysis to the mentor. Between 2012 and 2015 we have tested three versions of our prototype with longitudinal analyses of teams attending startup weekend competitions, to confirm that our prototype supports mentors with few and yet relevant information. The results of our studies open several avenues of research regarding rapid diagnostic of project teams, whereas, from a practical point of view, our prototype entirely done with Google Docs can be easily used by anyone interested in entrepreneurship education. Keywords: Entrepreneurship education, effectuation, mentoring, decision support, design science.

IS capability assessment - the MIND canvas

With the increasing ubiquity and growing pervasiveness of Information Systems (IS) in todays’ organisations, one of the capabilities of essential value to an organisation is its IS/IT (henceforth IS) capability. However, despite this increasing importance of the IS capability, research has barely focused on providing a measure for assessing the IT capability of an organization. In overview, IS capability has contributed significantly in understanding how information technology remains a valuable component of any modern day firm (Bharadwaj 2000, Santhanam and Hartono 2003). While these prior research focus in itself is of value in establishing the importance of IS capability, this current study posits that this research area is attaining maturity and it is about time we extend this stream to provide a measure for assessing and evaluating the IS capability that defines an organization. To borrow a quote from Peter Drucker - “if it can be measured; it can be improved”.

Designing and evaluating an interactive assessment instrument to improve the process for mobile service application innovation

Published Version

An overview of online-research in information systems

As the Internet has changed communication, commerce, and the distribution of information, so it is changing Information Systems Research (ISR). The goal of this paper is to put the topic of application and reliability of online research into the focus of ISR by exploring the extension of online research methods (ORM) into its popular publication outlets. 513 articles from high ranked ISR publication outlets from the last decade have been analyzed using online content analysis. The findings show that in ISR online research methods are applied despite the missing discussion on the validity of the theories and methods that were defined offline within the new environment and the associated challenges.

At the Vanguard of Design Science: First Impressions and Early Findings from Ongoing Research

Published Version

An túrscéal iar-nua-aoiseach sa Ghaeilge

Is éard atá curtha romham agam sa tráchtas seo ná an t-úrscéal iar-nua-aoiseach sa Ghaeilge a phlé; chun aitheantas a thabhairt don seánra mar rud ar leith; chun a fhréamhacha a aimsiú agus a thréithe sainiúla a léiriú. Féachaim anseo lena léiriú go bhfuil baint shainiúil ag an úrscéal iar-nua-aoiseach sa Ghaeilge le stair shochteangeolaíoch agus liteartha na hÉireann. Chruthaigh scríbhneoirí Béarla na hÉireann, ar nós Joyce, Beckett agus Flann O’Brien (Brian Ó Nualláin), cur chuige liteartha a raibh toradh ollmhór aige ar chúrsaí liteartha an domhain – go háirithe sa chomhthéacs (iar)-nua-aoiseach. Léireoidh mé gur tháinig an cur chuige seo chun cinn de bharr an choibhnis shainiúil atá ag muintir na hÉireann le teanga – coibhneas atá ginte i nguagacht faoin rud is teanga féin ann. Áitím gur eascair an ghuagacht seo as an athrú stádais – ó phríomhtheanga go mionteanga – a tharla don Ghaeilge. Áitím gur cruthaíodh feasacht ar fholús i bhféiniúlacht na tíre nuair a tharla an t-athrú sin agus go raibh tionchar ag an bhfeasacht seo ar litríocht na hÉireann – idir Ghaeilge agus Bhéarla. Is minic a fhéachann an túrscéal iar-nua-aoiseach, i ngach teanga ina gcleachtar a leithéid, le staidéar a dhéanamh ar na slite ina gcruthaítear brí sa saol trí theanga agus trí reacaireacht. Murab ionann is a mbíonn i gceist san úrscéal ‘traidisiúnta’ – an t-úrscéal ‘réadach’ mar a tuigtear leis – glacann iar-nua-aoiseachas leis go bhfuil solúbthacht agus saorgacht i ngach léiriú ar an mbrí seo. Léiríonn na húrscéalta atá faoi chaibidil sa tráchtas seo an-doimhneacht liteartha. Is saothair fhéinchomhfhiosacha agus mheitificseanúla iad a thaispeánann éiginnteacht i leith brí absalóidigh. Oibríonn siad mar léiriú ar fheidhm na teanga sa saol agus ar na slite ina gcruthaíonn gach reacaireacht a fírinne féin. Cé gur tréithe iar-nua-aoiseacha iad siúd, is tréithe iad chomh maith a bhaineann le stádas na mionteanga.

Estimating the magnitude of trastuzumab effects within patient subgroups in the HERA trial.

BACKGROUND: Trastuzumab (Herceptin(R)) improves disease-free survival (DFS) and overall survival for patients with human epidermal growth factor receptor 2 (HER2)-positive early breast cancer. We aimed to assess the magnitude of its clinical benefit for subpopulations defined by nodal and steroid hormone receptor status using data from the Herceptin Adjuvant (HERA) study. PATIENTS AND METHODS: HERA is an international multicenter randomized trial comparing 1 or 2 years of trastuzumab treatment with observation after standard chemotherapy in women with HER2-positive breast cancer. In total, 1703 women randomized to 1-year trastuzumab and 1698 women randomized to observation were included in these analyses. Median follow-up was 23.5 months. The primary endpoint was DFS. RESULTS: The overall hazard ratio (HR) for trastuzumab versus observation was 0.64 [95% confidence interval (CI) 0.54-0.76; P < 0.0001], ranging from 0.46 to 0.82 for subgroups. Estimated improvement in 3-year DFS in subgroups ranged from +11.3% to +0.6%. Patients with the best prognosis (those with node-negative disease and tumors 1.1-2.0 cm) had benefit similar to the overall cohort (HR 0.53, 95% CI 0.26-1.07; 3-year DFS improvement +4.6%, 95% CI -4.0% to 13.2%). CONCLUSIONS: Adjuvant trastuzumab therapy reduces the risk of relapse similarly across subgroups defined by nodal status and steroid hormone receptor status, even those at relatively low risk for relapse.

Disciplined Seeing: Forms of Christianity and Forms of Life

Beta-arrestins regulate atherosclerosis and neointimal hyperplasia by controlling smooth muscle cell proliferation and migration.

Atherosclerosis and arterial injury-induced neointimal hyperplasia involve medial smooth muscle cell (SMC) proliferation and migration into the arterial intima. Because many 7-transmembrane and growth factor receptors promote atherosclerosis, we hypothesized that the multifunctional adaptor proteins beta-arrestin1 and -2 might regulate this pathological process. Deficiency of beta-arrestin2 in ldlr(-/-) mice reduced aortic atherosclerosis by 40% and decreased the prevalence of atheroma SMCs by 35%, suggesting that beta-arrestin2 promotes atherosclerosis through effects on SMCs. To test this potential atherogenic mechanism more specifically, we performed carotid endothelial denudation in congenic wild-type, beta-arrestin1(-/-), and beta-arrestin2(-/-) mice. Neointimal hyperplasia was enhanced in beta-arrestin1(-/-) mice, and diminished in beta-arrestin2(-/-) mice. Neointimal cells expressed SMC markers and did not derive from bone marrow progenitors, as demonstrated by bone marrow transplantation with green fluorescent protein-transgenic cells. Moreover, the reduction in neointimal hyperplasia seen in beta-arrestin2(-/-) mice was not altered by transplantation with either wild-type or beta-arrestin2(-/-) bone marrow cells. After carotid injury, medial SMC extracellular signal-regulated kinase activation and proliferation were increased in beta-arrestin1(-/-) and decreased in beta-arrestin2(-/-) mice. Concordantly, thymidine incorporation and extracellular signal-regulated kinase activation and migration evoked by 7-transmembrane receptors were greater than wild type in beta-arrestin1(-/-) SMCs and less in beta-arrestin2(-/-) SMCs. Proliferation was less than wild type in beta-arrestin2(-/-) SMCs but not in beta-arrestin2(-/-) endothelial cells. We conclude that beta-arrestin2 aggravates atherosclerosis through mechanisms involving SMC proliferation and migration and that these SMC activities are regulated reciprocally by beta-arrestin2 and beta-arrestin1. These findings identify inhibition of beta-arrestin2 as a novel therapeutic strategy for combating atherosclerosis and arterial restenosis after angioplasty.

Improving the use of asset-building financial services by Latino immigrants in Langley Park, Maryland

Gemstone Team ANSWER Poverty (Assessing the Need for Services Which Effectively Reduce Poverty)

Real-time decision aid display

Gemstone Team Future Firefighting Advancements

Online and Traditional Lectures: Evaluating Effects of Social Presence and Learner Control

Online courses are rapidly replacing traditional, face-to-face lectures in American universities (Allen & Seaman, 2011). As technology improves, this trend will likely continue and accelerate. Researchers must evaluate the impact of online courses compared to their traditional counterparts. This two-part study quantifies the effect of two variables – social presence and learner control – on students’ recall, application and perceived learning levels in different lecture formats. Students in introductory courses at a four-year, public, American university were randomly assigned into three groups to view distinct lecture formats, one in a traditional classroom and two via the Internet. Upon viewing the single lecture, the students were asked to fill out a test and survey to quantify teacher immediacy, recall and application, and perceived learning levels across lecture formats. The study found that different levels of social presence and learner control affected students’ perceived learning levels but did not impact recall or application.