An die rechtlichen und verständigen Bewohner Wiens: Alle Folgen einer fürchterlichen Anarchie sind in der schrecklichsten Gestalt an Euch vorüber gezogen ...

Welsch (Projektbearbeiter): Aufruf des Militärgouverneurs Welden an die "rechtlichen und verständigen Bewohner Wiens" zur Unterstützung seiner Politik der Wiederherstellung von "Ordnung und Gesetz". "Ihr werdet die Stimme der Vernunft ... erkennen, und mich nicht zwingen, im Donner der Geschütze die Ordnung zu verkünden."

The Character of Christian-Muslim Encounter: Essays in Honour of David Thomas

The Character of Christian-Muslim Encounter is a Festschrift in honour of David Thomas, Professor of Christianity and Islam, and Nadir Dinshaw Professor of Inter Religious Relations, at the University of Birmingham, UK. The Editors have put together a collection of over 30 contributions from colleagues of Professor Thomas that commences with a biographical sketch and representative tribute provided by a former doctoral student, and comprises a series of wide-ranging academic papers arranged to broadly reflect three dimensions of David Thomas’ academic and professional work – studies in and of Islam; Christian-Muslim relations; the Church and interreligious engagement. These are set in the context of a focussed theme – the character of Christian-Muslim encounters – and cast within a broad chronological framework.

"Citizenship Lite" revisited

In a small book and article published in 2010, I argued that citizenship in the West was undergoing a process of "lightening": it has become easier to obtain, connotes fewer rights exclusively attached to it, and is capped by thin and thinning identities. In my presentation, I review the `citizenship lite` hypothesis in light of recent trends and scholarship.

Studies of the structure and function of a fibrinogen binding MSCRAMM(RTM) from Staphylococcus epidermidis

Coagulase-negative staphylococci (CNS) are recognized as important pathogens and are particularly associated with foreign body infections. S. epidermidis accounts for approximately 75% of the infections caused by CNS. Three genes, sdrF, sdrG, and sdrH, were identified by screening a S. epidermidis genomic library with a probe encompassing the serine-aspartate dipeptide repeat-encoding region (region R) of clfA from S. aureus. SdrG has significant amino acid identity to ClfA, ClfB and other surface proteins of S. aureus. SdrG is also similar to a protein (Fbe) recently described by Nilsson, et al. (Infection and Immunity, 1998, 66:2666–73) from S. epidermidis. The N-terminal domain (A region) of SdrG was expressed as a his-tag fusion protein in E. coli. In an ELISA, this protein, rSdrG(50-597) was shown to bind specifically to fibrinogen (Fg). Western ligand blot analysis showed that SdrG binds the Bβ chain of Fg. To further characterize the rSdrG(50-597)-Fg interaction, truncates of the Fg Bβ chain were made and expressed as recombinant proteins in E. coli. SdrG was shown to bind the full-length Bβ chain (1462), as well as the N-terminal three-quarters (1-341), the N-terminal one-half (1-220) and the N-terminal one-quarter (1-95) Bβ chain constructs. rSdrG(50-597) failed to bind to the recombinant truncates that lacked the N-terminal 25 amino acid residues of this polypeptide suggesting that SdrG recognizes a site within this region of the Bβ chain. Inhibition ELISAs have shown that peptide mimetics, including β1–25, and β6–20, encompassing this 25 residue region can inhibit binding of rSdrG(50-597) to Fg coated wells. Using fluorescence polarization we were able to determine an equilibrium constant (KD) for the interaction of rSdrG(50-597) with the Fg Bβ chain peptide β1–25. The labeled peptide was shown to bind to rSdrG(50-597) with a KD of 0.14 ± 0.01μM. Because rSdrG(50-597) recognizes a site in the Fg Bβ chain close to the thrombin cleavage site, we investigated the possibility of the rSdrG(50-597) site either overlapping or lying close to this cleavage site. An ELISA showed that rSdrG(50-597) binding to thrombin-treated Fg was significantly reduced. In a clot inhibition assay rSdrG(50-597) was able to inhibit fibrin clot formation in a concentration dependent manner. Furthermore, rSdrG(50-597) was able to inhibit clot formation by preventing the release of fibrinopeptide B as determined by HPLC. To further define the interaction between rSdrG(50-597) and peptide β6–20, we utilized an alanine amino acid replacement strategy. The residues in β6–20 that appear to be important in rSdrG(50-597) binding to Fg, were confirmed by the rSdrG(273-597)-β6–20 co-crystal structure that was recently solved by our collaborators at University of Alabama-Birmingham. Additionally, rSdrG(50-597) was not able to bind to Fg from different animal species, rather it bound specifically to human Fg in an ELISA. This suggests that the sequence variation between Fg Bβ chains of different species, specifically with in the N-terminal 25 residues, affects the ability of rSdrG(50-597) binding to Fg, and this may explain why S. epidermidis is primarily a human pathogen. ^

Ms. Ff. Mus. 1587 - [Arien und Duette]

[Georg Philipp Telemann]

Gruss aus Bayreuth : komm komm! holder Knabe

lass mich Dir blüh'n

Statins and myasthenia gravis

Introduction. 3-hydroxy-3-methylglutaryl CoA reductase inhibitor ("statin") have been widely used for hypercholesteroremia and Statin induced myopathy is well known. Whether Statins contribute to exacerbation of Myasthenia Gravis (MG) requiring hospitalization is not well known. ^ Objectives. To determine the frequency of statin use in patients with MG seen at the neuromuscular division at University of Alabama in Birmingham (UAB) and to evaluate any association between use of statins and MG exacerbations requiring hospitalization in patients with an established diagnosis of Myasthenia Gravis. ^ Methods. We reviewed records of all current MG patients at the UAB neuromuscular department to obtain details on use of statins and any hospitalizations due to exacerbation of MG over the period from January 1, 2003 to December 31, 2006. ^ Results. Of the 113 MG patients on whom information was available for this period, 40 were on statins during at least one clinic visit. Statin users were more likely to be older (mean age 60.2 vs 53.8, p = 0.029), male (70.0% vs 43.8%, p = 0.008), and had a later onset of myasthenia gravis (mean age in years at onset 49.8 versus 42.9, p = 0.051). The total number of hospitalizations or the proportion of subjects who had at least one hospitalization during the study period did not differ in the statin versus no-statin group. However, when hospitalizations which occurred from a suspected precipitant were excluded ("event"), the proportion of subjects who had at least one such event during the study period was higher in the group using statins. In the final Cox proportional hazard model for cumulative time to event, statin use (OR = 6.44, p <0.01) and baseline immunosuppression (OR = 3.03, p = 0.07) were found to increase the odds of event. ^ Conclusions. Statin use may increase the rate of hospitalizations due to MG exacerbation, when excluding exacerbations precipitated by other suspected factors.^

Notable College Experiences Through Original Still Photography

http://lib.dr.iastate.edu/carver_narratives/1000/thumbnail.jpg

Estructura y libertad : Sobre las afinidades entre el Free Cinema y los Estudios Culturales

Esta ponencia se concentra en un análisis del Free Cinema, procurando identificar las modificaciones que introdujo en el proceso de producción cinematográfica, su dimensión política y su afinidad con la reformulación crítica del marxismo emprendida por la Escuela de Birmingham. El Free Cinema es una corriente cinematográfica surgida en Gran Bretaña a mediados de la década de 1950, cuyas intenciones originales fueron explicitadas a través de una serie de manifiestos que acompañaron las primeras proyecciones del grupo. El manifiesto, punto de encuentro de las pasiones políticas y los impulsos estéticos, constituye un corpus privilegiado para iniciar un estudio de la articulación entre ambas dimensiones que luego se concentrará en las producciones audiovisuales. En primera instancia, la ponencia da cuenta de las rupturas formales y temáticas que caracterizan la irrupción del Free Cinema dentro del cine británico. A continuación, explora particularmente las transformaciones que supuso en los modos de representar y relacionarse con la clase obrera. Nos interesa rastrear cómo se manifiesta, en ese vínculo, un conjunto de asociaciones valorativas ligadas a formas específicas de alineamiento y compromiso político que colocan al Free Cinema en las proximidades de los Estudios Culturales

Estructura y libertad : Sobre las afinidades entre el Free Cinema y los Estudios Culturales

Esta ponencia se concentra en un análisis del Free Cinema, procurando identificar las modificaciones que introdujo en el proceso de producción cinematográfica, su dimensión política y su afinidad con la reformulación crítica del marxismo emprendida por la Escuela de Birmingham. El Free Cinema es una corriente cinematográfica surgida en Gran Bretaña a mediados de la década de 1950, cuyas intenciones originales fueron explicitadas a través de una serie de manifiestos que acompañaron las primeras proyecciones del grupo. El manifiesto, punto de encuentro de las pasiones políticas y los impulsos estéticos, constituye un corpus privilegiado para iniciar un estudio de la articulación entre ambas dimensiones que luego se concentrará en las producciones audiovisuales. En primera instancia, la ponencia da cuenta de las rupturas formales y temáticas que caracterizan la irrupción del Free Cinema dentro del cine británico. A continuación, explora particularmente las transformaciones que supuso en los modos de representar y relacionarse con la clase obrera. Nos interesa rastrear cómo se manifiesta, en ese vínculo, un conjunto de asociaciones valorativas ligadas a formas específicas de alineamiento y compromiso político que colocan al Free Cinema en las proximidades de los Estudios Culturales

Estructura y libertad : Sobre las afinidades entre el Free Cinema y los Estudios Culturales

Esta ponencia se concentra en un análisis del Free Cinema, procurando identificar las modificaciones que introdujo en el proceso de producción cinematográfica, su dimensión política y su afinidad con la reformulación crítica del marxismo emprendida por la Escuela de Birmingham. El Free Cinema es una corriente cinematográfica surgida en Gran Bretaña a mediados de la década de 1950, cuyas intenciones originales fueron explicitadas a través de una serie de manifiestos que acompañaron las primeras proyecciones del grupo. El manifiesto, punto de encuentro de las pasiones políticas y los impulsos estéticos, constituye un corpus privilegiado para iniciar un estudio de la articulación entre ambas dimensiones que luego se concentrará en las producciones audiovisuales. En primera instancia, la ponencia da cuenta de las rupturas formales y temáticas que caracterizan la irrupción del Free Cinema dentro del cine británico. A continuación, explora particularmente las transformaciones que supuso en los modos de representar y relacionarse con la clase obrera. Nos interesa rastrear cómo se manifiesta, en ese vínculo, un conjunto de asociaciones valorativas ligadas a formas específicas de alineamiento y compromiso político que colocan al Free Cinema en las proximidades de los Estudios Culturales

Polar light on Iceland and Faroer

Gelegentlich einer Diskussion über die Perioden der Polarlichterscheinungen und damit in Zusammenhang stehender Phänomene wurde die Meinung geäußert, daß die in verschiedenen Arbeiten abgeleiteten Perioden (insbesondere der Jahresgang der Nordlichthäufigkeit) möglicherweise nur örtlichen Charakter haben. Ich sah mich daher veranlaßt, bevor ich an eine zusammenfassende Darstellung des aus verschiedenen Gegenden der Nord- und Süd-Halbkugel stammenden Materials gehe, noch die aus Island und den Faer Oern vorliegenden Beobachtungen gesondert zu behandeln. Da die Bearbeitung nach dem gleichen Schema erfolgen kann wie die von mir in der "Polarforschung", Jahrgang 1948, veröffentlichte Arbeit über die in Grönland beobachteten Nordlichter, soll sie hier in stichwortartiger Kürze wiedergegeben werden.