Evaluation of CA-125 and soluble CD-23 in patients with pelvic endometriosis: a case-control study

Objective: To evaluate serum concentrations of CA-125 and soluble CD-23 and to correlate them with clinical symptoms, localization and stage of pelvic endometriosis and histological classification of the disease. Methods: Blood samples were collected from 44 women with endometriosis and 58 without endometriosis, during the first three days (1st sample) and during the 7th, 8th and 9th day (2nd sample) of the menstrual cycle. Measurements of CA-125 and soluble CD-23 were performed by ELISA. Mann-Whitney U test was used for age, pain evaluations (visual analog scale) and biomarkers concentrations. Results: Serum levels Of CA-125 were higher in endometriosis patients when compared to the control group during both periods of the menstrual cycle evaluated in the study. This marker was also elevated in women with chronic pelvic pain, deep dyspareunia (2nd sample), dysmenorrhea (both samples) and painful defecation during the menstrual flow (2nd sample). CA-125 concentration was higher in advanced stages of the disease in both samples and also in women with ovarian endometrioma. Concerning CD-23, no statistically significant differences were observed between groups. Conclusion: The concentrations of CA-125 were higher in patients with endometriosis than in patients without the disease. No significantly differences were observed for soluble CD-23 levels between groups.

Celebración del Día del Libro (23 de abril de 2010) en el programa de radio Hoy por hoy

Emisión en directo, desde la Sala Polivalente del Edificio Central de la Biblioteca Universitaria del programa de radio de la cadena Ser "Hoy por hoy", el viernes 23 de abril de 2010, de 11.15 a 13 horas. Este programa estuvo dedicado al Día del libro y al servicio público que presta la Biblioteca Universitaria. Contó con la presencia de la Vicerrectora de Cultura y Deporte, doña Isabel Pascua Febles, la Directora de la Biblioteca Universitaria, doña María del Carmen Martín Marichal y los bibliotecarios Fernando Barrera Luján, María Dolores Orihuela Millares, Víctor Macías Alemán y Avelina Fernández Manrique de Lara. En la primera parte del programa se anunció a los ganadores del "Primer Premio de Relato Corto" organizado por la Biblioteca Universitaria de Las Palmas de Gran Canaria y se les hizo entrega de sus respectivos premios. El Primero recayó en la obra titulada "El Pacto" de Fernando Fernández Rodríguez, presentada bajo el seudónimo Agustín. El segundo lo obtuvo la obra "Subtítulo" de José Iván Rodríguez Macario firmado con el seudónimo León Miranda. Ambos premios serán incluidos en el Repositorio Institucional Acceda.

Damage tolerance analysis for Blackshape BS 115 programme, EASA CS VLA & CS-23

The thesis project has been developed in partnership with the Design Department of Blackshape Spa, a carbon – fiber ultra – light airplane company in Monopoli (Bari, Italy). The main goal is the assessment of a starting point for a damage tolerant concept during the design and certification phases of the Blackshape BS 115 airplane, with respect to EASA CS VLA & CS 23 Regulations. This approach has been carried out starting from an initial literary review as far as the way of modeling composites fractures is concerned. Further on, three finite element models have been generated and implemented in order to simulate defects occurring during manufacturing and service phases. At last, the procedures of non - destructive inspections have been taken into account, in order to establish how to investigate primary structures defects and delaminations during maintenance.