Terapia fotodinâmica e luz branca: aspectos analíticos e perspectivas da viabilidade do tratamento

Photodynamic Therapy (PDT) is a technique used to treat several types of lesions, such as cancer, microbial control, and esthetic dentistry cases. The performance of PDT involves the use of a photosensitizer (PS), which mainly will be located in cancer cells and is irradiated with visible light. This process, when it occurs in the presence of oxygen triggers the formation of reactive oxygen species that are cytotoxic to cells. These species cause cell death and subsequent tumor necrosis. The use of white light as a light source for multispectral Photodynamic Therapy and its consequences to the photodynamic effect is not yet completely established, and therefore there is interest in studying the parameters involved for analyzing the best conditions for applying treatment. The wavelength is crucial to improve the therapeutic effect, since both the optical properties of the biological tissue as the PS depend on these parameters. For FS studied in this work (Photogem®) are most often used wavelengths in the red region, due to their larger penetration depth in biological tissue. Thus, the light source becomes a fundamental aspect, their choice depends on the specific application and is based on the tumor location, light dose to be delivered and FS chosen. Despite all the advantages presented by lasers, the fact of having an emission spectrum essentially monochrome makes only one possible transition possible for the absorption of FS is used. Therefore, more extensive light sources such as light emitting diodes (LED), could be better used in some cases the laser, with the additional advantage of a reduced cost. Therefore, the choice of the white LED comes from an emission spectrum that still wider LED colors defined by allowing greater use of the several absorption bands and with varying depths of operation, according to the wavelength... (Complete abstract click electronic access below)

Remoção de N-amoniacal em baixas concentrações de oxigênio dissolvido a partir do efluente de frigorífico bovino

This work aimed to develop a biological system for removal of ammonia nitrogen operating at low concentrations of dissolved oxygen. Thus, a biological upflow vertical reactor was built, in which the affluent pass through the support media until the top. Sludge from an anaerobic stabilization pond of a slaughterhouse unit in the city of Presidente Prudente - SP was used as inoculum. Initially the system operated in batch and afterwards in a continuous flow with different HRT. For feeding the reactor, an initial phases was adopted a synthetic culture media, described by Martins (2007), in order to establish the ideal conditions for the development of Anammox bacteria and subsequently, submitted to the system a slugde effluent of slaughterhouse. The results showed significant removal efficiency of N-NH4+, especially in the phase without recirculation of culture media, with an average of 71% removal, with the proportion of removal of N-NH4 +:N-NO2- average 1: 1,69. For the period of operation with effluent from the slaughterhouse, were not obtained satisfactory results, without confirmation of the proliferation of Anammox bacteria in the system, due to the high presences of organic matter in the same confirmed by high concentrations of COD

Avaliação dos danos por fluência da serpentina da caldeira da REVAP

The determination of the remaining life of equipment operating at high temperatures has been a great challenge for their owners. The use of safety factors, often conservative, makes the replacement of equipment or of its components at the end of the life of design gets financially unviable. This study aimed to estimate the remaining life of the serpentine of the secondary superheater of one of REVAP’s boilers (Henrique Lage Refinery), through accelerated creep tests and comparison of the results with the techniques based on microstructure and hardness. When conducting a proper assessment it’s possible to increase the equipment reliability, ensuring operational continuity and physical integrity. The tests showed a minimal residual life of 12.7 years (111,252 hours), longer than the design life (100,000 hours), even after a period of operation of approximately 250,000 hours, confirming the conservatism of the project. The techniques based on microstructure and hardness did not show good correlation with the creep test, decreasing the reliability of these techniques in determining the residual life

Espectrometria de massa para análise isotópica dos bio-elementos

Mass spectrometry is an analytical technique widely used in several areas of academic research. It allows the knowledge of the information about the micro-world of atoms leading to significant advances in science today. The analysis of stable isotopes of carbon, hydrogen, oxygen, nitrogen and sulfur, also known as bio-elements, shows itself as a major area of interest in using the proposed method. The development of techniques and equipment coupled with mass spectrometry promises to deliver even greater progress in this field, in particular, for the biological sciences and related areas. The pyrolytic method in reduction of organic compounds at high temperatures provides simultaneous isotopic analysis of bio-elements H and O, by the gases released, H2 and CO after the pyrolitic process, significantly reducing analysis time and the amount of material to sample. This paper presents a review of mass spectrometry with its basic principles of operation, and pyrolytic method for reducing compounds at temperatures above 1400 ° C for isotopic analysis of bio-elements

Relações-Públicas 3.0: a atuação do profissional na sociedade conectada

This work aims to reflect on the role of professional public relations in the context of connected information society and, therefore, understand how the internet has changed life in society, evaluating their impact on organizations, communication and public relations. Certainly the communication as a whole is no longer the same after the arrival of the online universe. Organizations, in turn, also are not out of context and begin to feel the impacts of such changes. Perform a reflection on the current situation and the practices and functions of public relations is fundamental to that in the midst of many technological innovations, do not ignore the essence of humanistic profession

Estudos das condições da disposição final de resíduos sólidos domiciliares no aterro sanitário de Cachoeira Paulista – SP

In this assignment, will be assessed the conditions of operation for the final disposal of household solid waste landfill in the city of Cachoeira Paulista-SP. The theme chosen for research is of great social importance therefore is directly related to the well-being of the people, sustainable development, environmental protection and public health. Everyone should be aware of the problems related to improper final disposal of solid waste of any kind. The objectives of the study were: analyse the conditions of operation of the landfill; verify the treatment technology of percolating liquids (slurry) generated in the landfill; examine whether the landfill obey the rules; which cities in the region depend on the disposal system, verify that there are flaws in the final destination of solid waste in the municipality and in the cities of the region. The research is primarily a bibliographic review, obtained by querying the database and virtual libraries. Technical visits were also held at the study site, to check spot the methodology employed in the operation of landfill This work concluded that for the period under study, the landfill was as a landfill site, therefore, in accordance with the rules of operation

Otimização de altitude de vôo para aeronaves executivas para economia de combustível e tempo

This work approaches, in a simplified manner, the analysis of an aircraft’s trajectory through the 3 main flight phases, climb, cruise and descent, related to fuel consumption and elapsed time. From this analysis is developed a tool that aims optimize the flight planning operational procedure, providing an altitude that comply with fuel saving during the trip, or minimizes the trip time. The use of any altitude is an operator’s decision, that aims comply with their operational needs of each trip, getting the results provided by the tool as a primary approach to the flight profile that also bring up economics aspects of each possibility of decision to be taken. Since the aeronautical Market has singular problems, as the flight altitude optimization, there is the need to solutions very customized that many times can not attend every restriction for each operator and its related kind of operation. When we talk about executive aircrafts, is possible to note that its operators does not have enough engineering and logistic support, when compared to huge airlines companies, to analyze all exceptions of each singular operation, creating many times wastes that can be avoiding with a tool described herein in this work

Girl rising: ciberativismo como forma de engajamento social

This analysis sought to study the social history of women, education and practice of cyber-activism, which consists of the struggle for causes that benefit society as a manner of social engagement. Through thorough theoretical study it was possible to analyze the campaign, 10X10, and relate the importance of the practice of personal commitment to support causes of global interest. Thus, it is possible to ascertain the relevance of actions via the Internet, its reach, its effectiveness and method of operation, providing voice and force to altruistic causes

Ética e trabalho: Concepção de uma antítese social

Pós-graduação em Serviço Social - FCHS

Alocação de modem PLC utilizando SNR em uma rede elétrica de baixa tensão

Pós-graduação em Engenharia Elétrica - FEIS

A história da didática no Instituto de Educação Leônidas do Amaral Vieira - Santa Cruz do Rio Pardo (1953-1975)

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

A região do Médio Tietê e os primeiros acordes paulistas: o Cururu

Pós-graduação em Geografia - IGCE

O processo de construção da Unesp Corporativa

The article presents São Paulo State University Corporate Education Program – UNESPCorp – whose target is to evolve the staff of institution in order of their professional improvement, using distance education technologies (D-learning). The UNESPCorp pilot project started with the Improvement in Bidding and Public Employment curse. The curse was taught on the second semester of 2012 and received 130 employees representing all UNESP campuses. The text was divided in two parts, the first part recovers historical context which introduces the Corporate University. The second part presents challenges and advances represented for the first version of course, even as its pedagogical structure of operation.

A educação e a sustentabilidade: o desafio de um paradigma e a década da educação para o desenvolvimento sustentável da UNESCO (2005-2014)

This paper aims at proposing a discussion on the role of education in a pragmatic plot. It intends to offer some contributions to the consolidation in the essence of sustainable development and of a contextualized sustainability as well as its respective dimensions. Therefore, some conceptual evolutions of such expressions and the implications for when they are being used, especially parallel to the UN Decade of Education for Sustainable Development, UNESCO (2005-2014) are presented. This paper also intends to promote some reflection on how much environmental and general education are important with regard to the challenge of multidimensional balance proposed, as seen from the perspective of a paradigm that has been constantly shaped since the Stockholm Conference of 1972, going through the given contributions in 1992 by The Earth Summit in Rio de Janeiro – Eco 92 / Rio 92; and from there to the United Nations Conference on Sustainable Development, of Rio+20, in 2012.

Paixão, mito e formas de vida em textos publicitários

The passion, understood by Aristotle, as a contingency which causes a change in the essence of the subject, was object of research of the Greek philosopher as rhetorical strategy used by the speaker to touch its listeners. The greimasian semiotics, enlarging the concept of Aristotle’s passion, understands it as the soul states of a subject that can be gathered form the analysis of a text. Reflections towards the passion discursivization and its persuasion effects in advertisements lead us to establish the relationships between passion, myth and ways of life.