Efeitos preventivos do exercício físico sobre as proteínas ciclooxigenase-2 (COX-2) e fator de crescimento de vasos derivado do endotélio (VEGF) no músculo cardíaco em ratos tratados com dexametasona

Dexamethasone (DEXA) is a synthetic glucocorticoid widely used in the handling of several drugs, for its proven benefits in fighting inflammation and allergies. Despite their benefits, their chronic use leads to several side effects that include changes in the body in the metabolism of carbohydrates, lipids and proteins. Moreover, being an anti-inflammatory, acts on the arachidonic acid pathway, reducing the expression of the enzyme cyclooxygenase (COX-2) and growth factor derived from the endothelium of blood vessels (VEGF) in various tissues. However, its effects on the myocardium are still uncertain. The physical training (PT), in turn, promotes effects contrary to those caused by chronic use of DEXA, however, little is known about the preventive effects of TF in the side effects of Dexa in the myocardium. Therefore, the aim of this study was to determine if the TF has the ability to prevent and/or mitigate the effects of Dexa in protein expression of COX-2 and VEGF in the myocardium. Forty animals were divided into 4 groups: sedentary control (SC), sedentary treated with Dexa (SD), trained control (TC) and Trained treated with Dexa (TD) and submitted to a protocol of physical training on the treadmill for 70 days (1 h/day-5 days per week, 60% of physical capacity) or kept sedentary. Over the past 10 days, rats were treated with Dexa (Decadron, 0.5 mg/kg per day, ip) or saline. During training the animals were weighed weekly and during treatment daily. At the end of treatment was made to measure fasting glucose levels of animals. The rats were killed with excess anesthesia and cardiac muscle was removed, weighed, homogenized, centrifuged and stored at -20° C for analysis of protein expression of VEGF and COX-2 by Western blotting technique. Treatment with dexamethasone caused a weight loss of 18% in sedentary animals and 13% in trained as well as elevated levels of fasting glucose in sedentary (88%). The TF was unable to mitigate the loss in...

Estado nutricional e produtividade de algodoeiro em função de diferentes espaçamentos e aplicação de regulador de crescimento

Strategies of cotton growth as row spacing and use of growth regulator are efficient when the knowledge of crop production potential as well as the amounts of nutrients content. The objective of this study was to evaluate the nutritional status of cotton DeltaOpal cultivar through leaf analysis of macronutrient, chlorophyll index and yield in relation to plant arrangement and managements of the growth regulator. The treatments consisted of plant arrangement: arrangement 1: 88,900 plant ha(-1) and row spacing at 0.9m, arrangement 2: 114,300 plant ha(-1) and row spacing at 0.7m, arrangement 3: 178,000 plant ha(-1) and row spacing at 0.45m; management of growth regulator (mepiquat chloride) at 1.0 L ha(-1) dose, concentration was50g L-1: a-no regulator application; b-single application at 70 days after emergency (d.a.e.); c-split application into four stages (35, 45, 55, and 65 d.a.e.). The reading reviews SPAD chlorophyll, leaf analysis of macronutrients and cotton yield were conducted in three agricultural years 2006/07, 2007/08 and 2008/09, under the experimental design of completely randomized blocks, in a 3x3 factorial scheme totaling up nine treatments with four replications. The reduction of row spacing and increasing plant density gives less absorption of potassium and sulfur by cotton crop. A single application of mepiquat chloride increase calcium leaf content. The split application of mepiquat chloride provides increased SPAD reading index, higher foliar magnesium concentration and highest seed cotton yield.

Efeitos de doses e formas de aplicação de reguladores de crescimento em uvas sem sementes, cv. BRS Clara, em região tropical

O objetivo deste trabalho foi avaliar o efeito do uso dos reguladores vegetais, ácido giberélico e tidiazuron, no tamanho de bagas da cultivar BRS Clara em Região Tropical. Os experimentos foram conduzidos em 2006 e 2007, na Estação Experimental de Viticultura Tropical, em Jales-SP, região noroeste do Estado de São Paulo, em plantas da cv. BRS Clara. Foram testadas diferentes concentrações de GA3 aplicadas isoladamente, combinadas com Crop Set ou tidiazuron, em aplicações únicas ou sequênciais (2 e 4 vezes). As avaliações foram feitas por ocasião da maturação das uvas, considerando-se a massa fresca dos cachos, dos engaços e das bagas, determinadas por meio de balança analítica; o comprimento e o diâmetro médio das bagas, utilizando-se de paquímetro; e o teor de sólidos solúveis (SS), por meio de refratômetro manual. Os experimentos foram conduzidos em delineamento experimental de blocos casualizados, representados por uma planta, com 15 repetições, no ano de 2006, e 10 repetições, no ano de 2007. Os dados foram submetidos à análise de variância e, para a comparação das médias dos tratamentos, foi utilizado o teste Skott Nott, ao nível de 5% de probabilidade. Observou-se que o uso dos reguladores promoveu o crescimento das bagas na cultivar BRS Clara em todos os tratamentos, diferindo da testemunha.

Estudo sobre os determinantes do investimento na indústria de transformação brasileira: análise setorial para o período de 1996 a 2012

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Taxa de crescimento axial pós-operatório de olhos com catarata congênita e do desenvolvimento submetidos a facectomia com implante de lente intra-ocular

Pós-graduação em Pesquisa e Desenvolvimento (Biotecnologia Médica) - FMB

Aplicação da análise de jarabak, no estudo da relação entre a altura total facial anterior e posterior, em pacientes portadores de má-oclusão de classe I e classe II divisão 1 de angle, por meio de radiografias cefalométricas

ln order to predict the facial growth using Jarahak's analysis, cephalometric radiographies of 120 subjects during the mixed dentition and between 6 and 10 years of age were studied. From the total, 60 subjects (30 males and 30 females) were classified as Angle's Class I and 60 subjects (30 males and 30 females) were classified as Angle's Class II, Division 1. AIl subjects did not receive any orthodontic treatment. The proportion between anterior and posterior facial heigth (SGo-NMe) was studied, which is determined by the formula PFH x 100/ AFH = %, neither being straight (> 62% < 65), clockwise ( > 58% < 62%) and anti-clockwise ( > 65% - 80%). Mean average, standard deviation and facial height proportion (SGo - NMe) were determined for males and females according to Angle's classification of malocc!usion. Sexual dimorphism was examined with regard to different types of Angle's malocclusion and the direction of the facial growth, and the correlation of four cephalometrics measurements were analvsed

Análise sobre a importância do gerenciamento de resíduos de construção e demolição na universidade

With the growth of settlements and the consequent rise in civilian buildings, there was a need to allocate appropriately the waste arising from construction and demolition. Failure to meet the standards set about building waste generate social, economic and environmental impacts of remediation difficult. This study aimed to attend the importance of holding management programs involving the waste of construction and demolition at the University by the resulting environmental, economic and social benefits, and analysis of the main stages of Waste Management of Construction and Demolition, whose based on the National Solid Waste Policy, as well as verification of the importance of implementing these steps in the design of works, assisting in future studies of this type of waste and the problems accompanying the University

Análise do impacto do comércio eletrônico na economia: um estudo sobre o varejo de moda e o poder de influência dos blogs

This study addresses the topic of e-commerce as a competitive strategy for companies seeking innovation and to reach new markets. In last few years, the e-commerce has intensified in Brazil, as a result, many companies have adapted to that new market demand and have invested in new strategies. An example, is the use of social medias to promote the products, specifically the fashion retail industry, which promotes its products through partnerships with fashion blogs. To prove this new market trend, based on researches and indicators, this study will present growth data of e-commerce in Brazil, the fashion industry characteristics and the influence of blogs to increase sales, to further, understand its relation to the growth in e-commerce of fashion and future expectations

Descrição e análise de contingências presentes em legislações referentes à mobilidade urbana

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Sarcoma histiocítico: análise molecular pela técnica de hibridação genômica comparativa, microRNA e imunoistoquímica

Pós-graduação em Patologia - FMB

Carta de compartimentação fisiográfica na escala 1:50.000 a partir da análise integrada na bacia do Ribeirão de Araras (SP)

Pós-graduação em Geociências e Meio Ambiente - IGCE

Análise de desempenho de redes de comunicação wireless em aplicações de Smart Grid

Pós-graduação em Engenharia Elétrica - FEIS

Análise da Frequência de Polimorfismos nos genes IL28B e IL28R1 em pacientes acometidos por Meningioma

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Análise hormonal, imunolocalização e quantificação dos receptores de andrógenos (AR) e estrógenos (ER-α E ER-β) em ovário e útero de ratas submetidas a diferentes doses de decanoato de nandrolona: avaliação nos períodos pós-tratamento e pós-recuperação

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Efeito de parâmetros variáveis de fermentação sobre o crescimento celular e composição química do fermentado de batata-doce

This study aimed to evaluate the use of sweet potato as a substrate for the production of spirits. In order to promote an alternative technologically feasible, an experimental design was performed to minimize the operations of preparation, defining the most adequate conditions for the fermentation process. From sweet potato flour obtained by milling and dehydration process of the roots was carried out an enzymatic process of hydrolysis-saccharification of suspension of sweet potato flour with 18% dry matter. The hydrolyzate was used in the fermentation process which followed the 23 full factorial experimental design with central and axial points, and the independent variables were the concentration of reducing sugars, concentration of viable yeast and fermentation temperature. The dependent variables were viable cells, residual sugar, ethanol, glycerol and methanol. The dependent variables were quantified by liquid chromatography. The data analysis indicate that the best fermentation conditions among the tested conditions were: concentration of yeast 5 x 107-1 x 108 in number of viable cells, total reducing sugars from 12.5 to 13.5% and temperature between 33 -34ºC.