N-dimensional animal energetic niches clarify behavioural options in a variable marine environment

Animals respond to environmental variation by exhibiting a number of different behaviours and/or rates of activity, which result in corresponding variation in energy expenditure. Successful animals generally maximize efficiency or rate of energy gain through foraging. Quantification of all features that modulate energy expenditure can theoretically be modelled as an animal energetic niche or power envelope; with total power being represented by the vertical axis and n-dimensional horizontal axes representing extents of processes that affect energy expenditure. Such an energetic niche could be used to assess the energetic consequences of animals adopting particular behaviours under various environmental conditions. This value of this approach was tested by constructing a simple mechanistic energetics model based on data collected from recording devices deployed on 41 free-living Magellanic penguins (Spheniscus magellanicus), foraging from four different colonies in Argentina and consequently catching four different types of prey. Energy expenditure was calculated as a function of total distance swum underwater (horizontal axis 1) and maximum depth reached (horizontal axis 2). The resultant power envelope was invariant, irrespective of colony location, but penguins from the different colonies tended to use different areas of the envelope. The different colony solutions appeared to represent particular behavioural options for exploiting the available prey and demonstrate how penguins respond to environmental circumstance (prey distribution), the energetic consequences that this has for them, and how this affects the balance of energy acquisition through foraging and expenditure strategy.

Recognition from appearance subspaces across image sets of variable scale

Linear subspace representations of appearance variation are pervasive in computer vision. In this paper we address the problem of robustly matching them (computing the similarity between them) when they correspond to sets of images of different (possibly greatly so) scales. We show that the naïve solution of projecting the low-scale subspace into the high-scale image space is inadequate, especially at large scale discrepancies. A successful approach is proposed instead. It consists of (i) an interpolated projection of the low-scale subspace into the high-scale space, which is followed by (ii) a rotation of this initial estimate within the bounds of the imposed “downsampling constraint”. The optimal rotation is found in the closed-form which best aligns the high-scale reconstruction of the low-scale subspace with the reference it is compared to. The proposed method is evaluated on the problem of matching sets of face appearances under varying illumination. In comparison to the naïve matching, our algorithm is shown to greatly increase the separation of between-class and within-class similarities, as well as produce far more meaningful modes of common appearance on which the match score is based.

Allosteric Modulation of the HIV-1 gp120-gp41 Association Site by Adjacent gp120 Variable Region 1 (V1) N-Glycans Linked to Neutralization Sensitivity

The HIV-1 gp120-gp41 complex, which mediates viral fusion and cellular entry, undergoes rapid evolution within its external glycan shield to enable escape from neutralizing antibody (NAb). Understanding how conserved protein determinants retain functionality in the context of such evolution is important for their evaluation and exploitation as potential drug and/ or vaccine targets. In this study, we examined how the conserved gp120-gp41 association site, formed by the N- and Cterminal segments of gp120 and the disulfide-bonded region (DSR) of gp41, adapts to glycan changes that are linked to neutralization sensitivity. To this end, a DSR mutant virus (K601D) with defective gp120-association was sequentially passaged in peripheral blood mononuclear cells to select suppressor mutations. We reasoned that the locations of suppressors point to structural elements that are functionally linked to the gp120-gp41 association site. In culture 1, gp120 association and viral replication was restored by loss of the conserved glycan at Asn136 in V1 (T138N mutation) in
conjunction with the L494I substitution in C5 within the association site. In culture 2, replication was restored with deletion of the N139INN sequence, which ablates the overlapping Asn141-Asn142-Ser-Ser potential N-linked glycosylation sequons in
V1, in conjunction with D601N in the DSR. The 136 and 142 glycan mutations appeared to exert their suppressive effects by altering the dependence of gp120-gp41 interactions on the DSR residues, Leu593, Trp596 and Lys601. The 136 and/or 142
glycan mutations increased the sensitivity of HIV-1 pseudovirions to the glycan-dependent NAbs 2G12 and PG16, and also pooled IgG obtained from HIV-1-infected individuals. Thus adjacent V1 glycans allosterically modulate the distal gp120-
gp41 association site. We propose that this represents a mechanism for functional adaptation of the gp120-gp41 association site to an evolving glycan shield in a setting of NAb selection.

The dependent variable in social media use

What is the dependent variable in social media use? From a research perspective, this is a pertinent question to help explain and understand the behaviors that underpin the widespread adoption and use of social media throughout society. From a practical
perspective, the question is relevant for social media technology providers, for businesses that use social media, and community organizations that turn towards social media to reach out to their constituents. We propose the construct 'sense of community' as the dependent variable, which is reflected in four sub-constructs related to the behaviors of social media users. These behaviors are information seeking, hedonic activities, sustaining of strong ties and extending weak ties. Empirical evidence for these constructs comes from a survey of social media use by 18-25 year-olds in Indonesia, a ,country with exceptionally high utilization of social media. We outline practical implications of the  findings and areas for further theoretical development.

On some properties of weighted averaging with variable weights

Density-based means have been recently proposed as a method for dealing with outliers in the stream processing of data. Derived from a weighted arithmetic mean with variable weights that depend on the location of all data samples, these functions are not monotonic and hence cannot be classified as aggregation functions. In this article we establish the weak monotonicity of this class of averaging functions and use this to establish robust generalisations of these means. Specifically, we find that as proposed, the density based means are only robust to isolated outliers. However, by using penalty based formalisms of averaging functions and applying more sophisticated and robust density estimators, we are able to define a broader family of density based means that are more effective at filtering both isolated and clustered outliers. © 2014 Elsevier Inc. All rights reserved.