998 resultados para Soufrie`re Hills volcano
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Rituximab is an effective treatment of rheumatoid arthritis (RA), which has been approved for the treatment of moderate to severe disease in patients with an inadequate response to anti-TNF therapies. Rituximab differs from other available biological agents for RA by way of its unique mode of action and unrivalled long dosing interval. The efficacy of rituximab subsides progressively over time and re-therapy is generally required to maintain long term disease control. The timing of re-treatment is currently not well established and varies widely in clinical practice. The present document is a concise recommendation regarding re-treatment with rituximab, based on validated outcomes such as the DAS28 and the EULAR response criteria. The recommendation was established through consensus between practitioners familiar with rituximab therapy in RA. Optimisation of the rituximab re-treatment schedule may improve patient outcomes and balance risks and benefits for the individual patient.
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Patients affected with intra-thoracic recurrences of primary or secondary lung malignancies after a first course of definitive radiotherapy have limited therapeutic options, and they are often treated with a palliative intent. Re-irradiation with stereotactic ablative radiotherapy (SABR) represents an appealing approach, due to the optimized dose distribution that allows for high-dose delivery with better sparing of organs at risk. This strategy has the goal of long-term control and even cure. Aim of this review is to report and discuss published data on re-irradiation with SABR in terms of efficacy and toxicity. Results indicate that thoracic re-irradiation may offer satisfactory disease control, however the data on outcome and toxicity are derived from low quality retrospective studies, and results should be cautiously interpreted. As SABR may be associated with serious toxicity, attention should be paid for an accurate patients' selection.
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[Acte royal. 1574-09-10. Lyon]
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Contient : « Ci commance en françois le livre du noble Végèce, touchant le fait de la chose militaire, ordonné en quatre parties par tiltres et par chapitres. [L]e premier livre ensaigne à eslire les jouvenceaux... » ; « Ci commence les prologues du premier livre. [L]es anciens ont esté coustumier de mettre en escript... » ; «... treuve plus de l'art en ces choses, que l'ancienne dottrine ne nous en a monstré. Explicit »
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[Entrée. Henri III (roi de France). [15??]. Mantoue]
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Puteanus
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D. Dufresne