Monitoramento in vivo por imagem por ressonância magnética de células C6 de glioma marcadas com nanopartículas superparamagnéticas de óxido de ferro

OBJECTIVE: The aim of the current study was to monitor the migration of superparamagnetic iron oxide nanoparticle (SPION)-labeled C6 cells, which were used to induce glioblastoma tumor growth in an animal model, over time using magnetic resonance imaging (MRI), with the goal of aiding in tumor prognosis and therapy. METHODS: Two groups of male Wistar rats were used for the tumor induction model. In the first group (n=3), the tumors were induced via the injection of SPION-labeled C6 cells. In the second group (n=3), the tumors were induced via the injection of unlabeled C6 cells. Prussian Blue staining was performed to analyze the SPION distribution within the C6 cells in vitro. Tumor-inducing C6 cells were injected into the right frontal cortex, and subsequent tumor monitoring and SPION detection were performed using T2- and T2*-weighted MRI at a 2T field strength. In addition, cancerous tissue was histologically analyzed after performing the MRI studies. RESULTS: The in vitro qualitative evaluation demonstrated adequate distribution and satisfactory cell labeling of the SPIONs. At 14 or 21 days after C6 injection, a SPION-induced T2- and T2*-weighted MRI signal reduction was observed within the lesion located in the left frontal lobe on parasagittal topography. Moreover, histological staining of the tumor tissue with Prussian Blue revealed a broad distribution of SPIONs within the C6 cells. CONCLUSION: MRI analyses exhibit potential for monitoring the tumor growth of C6 cells efficiently labeled with SPIONs.

Imagem jornalística e representações sociais: a imagem dos Sertões

Este estudo tem o objetivo de analisar as representações sociais que a imprensa de circulação nacional faz dos Sertões do Nordeste nas reportagens de alcance nacional. A pesquisa está fundamentada na teoria das Representações Sociais, imagem fotográfica e jornalismo. Trata-se de um estudo de caso que analisa as imagens fotográficas disponíveis pela agência Globo e o jornal O Globo em seu portal online de notícias. São analisadas as temáticas, títulos e subtítulos de todas as fotografias disponíveis no site, correspondentes ao tema Sertão no período de 2003 a 2010. O estudo evidenciou que as imagens denotam uma representação do Sertão como local de isolamento, de seca, miséria, sem acesso a tecnologia, a saneamento, com sistema precário de transporte e rudimentares práticas agrícolas.

A complete CMOS UWB timed-array transmitter with a 3D Vivaldi antenna array for electronic high-resolution beam spatial scanning

We present a new Ultra Wide Band (UWB) Timed- Array Transmitter System with Beamforming capability for high-resolution remote acquisition of vital signals. The system consists of four identical channels, where each is formed of a serial topology with three modules: programmable delay circuit (PDC or τ), a novel UWB 5th Gaussian Derivative order pulse generator circuit (PG), and a planar Vivaldi antenna. The circuit was designed using 0.18μm CMOS standard process and the planar antenna array was designed with filmconductor on Rogers RO3206 substrate. Spice simulations results showed the pulse generation with 104 mVpp amplitude and 500 ps width. The power consumption is 543 μW, and energy consumption 0.27 pJ per pulse using a 2V power supply at a pulse repetition rate (PRR) of 100 MHz. Electromagnetic simulations results, using CST Microwave (MW) Studio 2011, showed the main lobe radiation with a gain maximum of 13.2 dB, 35.5º x 36.7º angular width, and a beam steering between 17º and -11º for azimuthal (θ) angles and 17º and -18º for elevation (φ) angles at the center frequency of 6 GHz

Diseño de un Amplificador de Bajo Ruido de Ultra Banda Ancha para un Receptor de UWB en CMOS 0.35 μm

Presentación del Proyecto Fin de Carrera titulado "Diseño de un Amplificador de Bajo Ruido de Ultra Banda Ancha para un Receptor de UWB en CMOS 0.35 μm"

Diseño, medida y verificación de un mezclador en CMOS 0.35 um para un receptor basado en el estándar IEEE 802.11a

Proyecto y presentación del Proyecto Fin de Carrera titulado "Diseño, medida y verificación de un mezclador en CMOS 0.35 um para un receptor basado en el estándar IEEE 802.11a"

Diseño de un mezclador pasivo en CMOS 0.35 um para un receptor basado en el estándar IEE802.11a

Memoria y presentación del Proyecto Fin de Carrera titulado "Diseño de un mezclador pasivo en CMOS 0.35 um para un receptor basado en el estándar IEE802.11a"

Diseño de un amplificador operacional totalmente integrado CMOS que funcione como driver para cargas capacitivas elevadas

Presentación del Proyecto Fin de Carrera titulado "Diseño de un Amplificador Operacional totalmente integrado CMOS que funcione como driver para cargas capacitivas elevadas"

Diseño de un convertidor de corriente en tecnología CMOS 0.35

Proyecto y presentación del Proyecto Fin de Carrera titulado "Diseño de un convertidor de corriente en tecnología CMOS 0.35"

Diseño del Amplificador de Bajo Ruido y del Mezclador para un Receptor de UWB en CMOS 0.18um

Especialidad: Sistemas electrónicos

Diseño de un mezclador basado en convertidores de corriente en tecnología CMOS 0.18UM

Proyecto y presentación del Proyecto Fin de Carrera titulado "DISEÑO DE UN MEZCLADOR BASADO EN CONVERTIDORES DE CORRIENTE EN TECNOLOGÍA CMOS 0.18UM"

Diseño de un filtro integrado sintonizable en tecnología CMOS 0.35μm

Especialidad: Sistemas Electrónicos