Ein offener Brief an Rothschild: Zu den merkwürdigen Veränderungen der letzten Zeit, welche ganz Europa umstalteten, gehört auch der große Verlust, den das Haus Rothschild erlitten ...

Welsch (Projektbearbeiter): Vergleich der gemeinnützigen Aktivitäten des Bankiers Rothschild mit denen des verstorbenen Wiener Industriellen und Philanthropen Herman Tedesco: "... jeder Bedrängte erhielt da eine Unterstützung; den Herrn Baron aber [Rothschild] kann man nur in Geschäftsangelegenheiten sprechen ... Eine Vergrößerung der jährlichen Spenden mit 100.000 fl. Conv. Münze würde diesem Manne [Rothschild] auch jetzt nichts schaden und sehr viel Elend von den Leidenden abwenden"

Aufklärung und Judenfrage

Hannah Arendt

Eine sozialtopographische Analyse der Wohngebiete von Nuzi

The archaeological evidence from Late Bronze Age Nuzi has ever since the publication of R.F.S. Starr’s final report in 1939 experienced few attention, leaving the interpretation of the inner structure of this extraordinarily extensively excavated settlement to a thriving philological research. This paper presents a macroscopic spatial analysis of mobile inventories in the domestic areas. Based on the comparison with stationary installations and the formal architectural structure a revised socio-topography is proposed. The combination with the evidence from the investigations of the private archives elucidates the great potential for the consideration of multiple approaches in the future research on the function, meaning and sociology of spaces in Near Eastern Archaeology.

Fieldwork in Upstate New York: Methods

production and perception experiments for the NCS and Low Back Merger in Ogdensburg, NY

Hs. Rothschild 4° 35 - Katalog der Bibliothek des Musikdirektors Dr. H. Henkel zu Frankfurt am Main

Vorbesitzer: Dr. H. Henkel; Freiherrlich Carl von Rothschild'sche Bibliothek Frankfurt am Main (Bibliothek für Neuere Sprachen und Musik, Frankfurt am Main); alte Signatur: Hs in 4° 35; Akzessionsnummer: 20229

Hs. Rothschild 4° 37 - Bibliothèque de Madame la Baronne Adélaïde de Rothschild [Catalogue]

Vorbesitzer: Adélaïde de Rothschild; Freiherrlich Carl von Rothschild'sche Bibliothek Frankfurt am Main; alte Signatur: 81; Hs in 4° 37; Akzessionsnummer: X19125

Hs. Rothschild 4° 38 - Bibliothèque de Madame la Baronne Adélaïde de Rothschild [Catalogue]

Vorbesitzer: Adélaïde de Rothschild; Freiherrlich Carl von Rothschild'sche Bibliothek Frankfurt am Main; alte Signatur: 82; Hs in 4° 38; Akzessionsnummer: X19126

STXBP1 encephalopathy: A neurodevelopmental disorder including epilepsy

OBJECTIVE To give a comprehensive overview of the phenotypic and genetic spectrum of STXBP1 encephalopathy (STXBP1-E) by systematically reviewing newly diagnosed and previously reported patients. METHODS We recruited newly diagnosed patients with STXBP1 mutations through an international network of clinicians and geneticists. Furthermore, we performed a systematic literature search to review the phenotypes of all previously reported patients. RESULTS We describe the phenotypic features of 147 patients with STXBP1-E including 45 previously unreported patients with 33 novel STXBP1 mutations. All patients have intellectual disability (ID), which is mostly severe to profound (88%). Ninety-five percent of patients have epilepsy. While one-third of patients presented with Ohtahara syndrome (21%) or West syndrome (9.5%), the majority has a nonsyndromic early-onset epilepsy and encephalopathy (53%) with epileptic spasms or tonic seizures as main seizure type. We found no correlation between severity of seizures and severity of ID or between mutation type and seizure characteristics or cognitive outcome. Neurologic comorbidities including autistic features and movement disorders are frequent. We also report 2 previously unreported adult patients with prominent extrapyramidal features. CONCLUSION De novo STXBP1 mutations are among the most frequent causes of epilepsy and encephalopathy. Most patients have severe to profound ID with little correlation among seizure onset, seizure severity, and the degree of ID. Accordingly, we hypothesize that seizure severity and ID present 2 independent dimensions of the STXBP1-E phenotype. STXBP1-E may be conceptualized as a complex neurodevelopmental disorder rather than a primary epileptic encephalopathy.

Schreiben Sr. Excellenz des Kaiserl. Österreichischen Finanzministers Herrn Grafen von Stadion an die Herren Finanzräthe Amschel und Salomon Mayer von Rothschild in Frankfurt am Main

Johann Philipp von Stadion

Hs. Rothschild 2° 63 Bd. 2 - Sammlung von Costümblättern

Vorbesitzer: Freiherrlich Carl von Rothschild'sche Bibliothek Frankfurt am Main; Akzessionsnummer: x18722; Bemerkung: Maße ohne Passepartout

Metabolic and hormonal response to intermittent high-intensity and continuous moderate intensity exercise in individuals with type 1 diabetes: a randomised crossover study.

AIMS/HYPOTHESIS To investigate exercise-related fuel metabolism in intermittent high-intensity (IHE) and continuous moderate intensity (CONT) exercise in individuals with type 1 diabetes mellitus. METHODS In a prospective randomised open-label cross-over trial twelve male individuals with well-controlled type 1 diabetes underwent a 90 min iso-energetic cycling session at 50% maximal oxygen consumption ([Formula: see text]), with (IHE) or without (CONT) interspersed 10 s sprints every 10 min without insulin adaptation. Euglycaemia was maintained using oral (13)C-labelled glucose. (13)C Magnetic resonance spectroscopy (MRS) served to quantify hepatocellular and intramyocellular glycogen. Measurements of glucose kinetics (stable isotopes), hormones and metabolites complemented the investigation. RESULTS Glucose and insulin levels were comparable between interventions. Exogenous glucose requirements during the last 30 min of exercise were significantly lower in IHE (p = 0.02). Hepatic glucose output did not differ significantly between interventions, but glucose disposal was significantly lower in IHE (p < 0.05). There was no significant difference in glycogen consumption. Growth hormone, catecholamine and lactate levels were significantly higher in IHE (p < 0.05). CONCLUSIONS/INTERPRETATION IHE in individuals with type 1 diabetes without insulin adaptation reduced exogenous glucose requirements compared with CONT. The difference was not related to increased hepatic glucose output, nor to enhanced muscle glycogen utilisation, but to decreased glucose uptake. The lower glucose disposal in IHE implies a shift towards consumption of alternative substrates. These findings indicate a high flexibility of exercise-related fuel metabolism in type 1 diabetes, and point towards a novel and potentially beneficial role of IHE in these individuals. TRIAL REGISTRATION ClinicalTrials.gov NCT02068638 FUNDING: Swiss National Science Foundation (grant number 320030_149321/) and R&A Scherbarth Foundation (Switzerland).

Endovascular stent reconstruction of a chronic total occlusion of the inferior vena cava using bidirectional wire access and a balloon puncture by a re-entry device.

Venous angioplasty with stenting of iliac veins is an important treatment option for patients suffering from post-thrombotic syndrome due to chronic venous obstruction. Interventional treatment of a chronically occluded vena cava, however, is challenging and often associated with failure. We describe a case of a chronic total occlusion of the entire inferior vena cava that was successfully recanalized using bidirectional wire access and a balloon puncture by a re-entry catheter to establish patency of the inferior vena cava.

Dysphagia in Acute Stroke: Incidence, Burden and Impact on Clinical Outcome.

BACKGROUND Reported frequency of post-stroke dysphagia in the literature is highly variable. In view of progress in stroke management, we aimed to assess the current burden of dysphagia in acute ischemic stroke. METHODS We studied 570 consecutive patients treated in a tertiary stroke center. Dysphagia was evaluated by using the Gugging Swallowing Screen (GUSS). We investigated the relationship of dysphagia with pneumonia, length of hospital stay and discharge destination and compared rates of favourable clinical outcome and mortality at 3 months between dysphagic patients and those without dysphagia. RESULTS Dysphagia was diagnosed in 118 of 570 (20.7%) patients and persisted in 60 (50.9%) at hospital discharge. Thirty-six (30.5%) patients needed nasogastric tube because of severe dysphagia. Stroke severity rather than infarct location was associated with dysphagia. Dysphagic patients suffered more frequently from pneumonia (23.1% vs. 1.1%, p<0.001), stayed longer at monitored stroke unit beds (4.4±2.8 vs. 2.7±2.4 days; p<0.001) and were less often discharged to home (19.5% vs. 63.7%, p = 0.001) as compared to those without dysphagia. At 3 months, dysphagic patients less often had a favourable outcome (35.7% vs. 69.7%; p<0.001), less often lived at home (38.8% vs. 76.5%; p<0.001), and more often had died (13.6% vs. 1.6%; p<0.001). Multivariate analyses identified dysphagia to be an independent predictor of discharge destination and institutionalization at 3 months, while severe dysphagia requiring tube placement was strongly associated with mortality. CONCLUSION Dysphagia still affects a substantial portion of stroke patients and may have a large impact on clinical outcome, mortality and institutionalization.