Efeito da água ozonizada e gluconato de clorexidina sobre propriedades mecânicas e microbiológicas de materiais utilizados para confecção de próteses odontológicas

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Cytotoxic and genotoxic effects of ethanolic extract of Euphorbia hyssoptfolia L. on HepG2 cells

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

C-2, N-dimethylbenzylamine cyclopalladated compounds: evaluation of cytotoxic, mutagenic and antitubercular activities

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Produção de chapas de partículas com resíduos de madeira Cordia goeldiana

The aim of this research consisted in the use of wastes from tropical wood (Cordia goeldiana) with low density and the polyurethane resin (mono and bicomponent) castor oil based in the manufacture of particleboards, generating subsidies as application in rural and civil construction, as well in the furniture industry. The particleboards were manufactured with 15% of polyurethane resin content (one part of pre-polymer and one part of polyol), compaction pressure of 4MPa, pressing temperature of 90 degrees C and press time of 7 minutes. The physical and mechanical properties investigated were density, moisture content, strength modulus in bending and internal bond, both obtained according to the recommendations of the Brazilian standard ABNT NBR 14810:2002. The mean values obtained for these properties were systematically superior to the Brazilian standard requirement. This point showed that it is possible the use of Cordia goeldiana wastes in the particleboard production. We confirmed the hypothesis of a significant linear relation between density and the internal bond of the panels, allowing the estimation of the internal bond of particleboards.

Thermal study and characterization of nicotinates of some alkaline earth metals using TG-DSC-FTIR and DSC-system photovisual

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Andropogon grass consortium with stylo in two times: the forage response and sources of phosphorus rates

The use of legumes intercropped with forage in the Brazilian savannah (Cerrado) region is an alternative to reverse the process of pasture degradation. The natural phosphorus deficiency in this region and the high retention capacity of this nutrient in the soil are factors that directly affect the sustainability of the production system. The objective of this study was to evaluate the effect of a phosphate with medium solubility (Arad) compared to more soluble sources such as triple superphosphate and mono-ammonium phosphate, on the formation and maintenance of pastures of Andropogon gayanus with or without the introduction of Stylosantes guianensis in pasture already established in the Brazilian savannah. Two experiments were carried out under field conditions in an Oxisol using a randomized block design with split plots, plots with two sources of phosphorus (Arad and super-triple or MAP) and subplots with different levels of phosphorus. The study showed that andropogon grass, even though characterised as forage requiring low fertilization, responded to increased fertilization, especially with the use of more soluble sources of P at planting. From the second year on, with the introduction of Stylosantes guianensis, verified effects were seen on legumes in their efficiency of utilization of residual fertilization from the first year; however, this didn't affect legume dry matter production resulting from the P sources used for the andropogon grass. The mixed stands of andropogon grass and Stylosantes guianensis made it more advantageous to increase the P sources using phosphate fertilizer with lower solubility (Arad), when compared to MAP.

Degradabilidade ruminal da matéria seca de folhas e colmo de genótipos de Cynodon spp. em quatro idades de rebrota

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

Características morfogênicas e estruturais da Brachiaria brizantha cv. Marandu submetida a diferentes doses de nitrogênio e alturas de resíduos

The objective of this study was to evaluate the rate of leaf appearance, leaf elongation rate, number of green leaves, length of blade and stem of Brachiaria brizantha cv. Marandu under different nitrogen levels and two residue heights. A randomized block design was used in a 4 x 2 factorial scheme, four doses of nitrogen (100, 200, 300 and 400 kg N ha(-1) year(-1)) and two residue heights (5 and 15 cm). There was significant interaction between residue height and nitrogen levels for leaf appearance rate of signal grass, which was influenced negatively and linearly by the residue heights being observed an average reduction of 28.20% from lower to higher residue. There was no interaction between the levels of nitrogen x residue height on the number of green leaves. The dosage that provided the highest stalk in the residue height of 5 cm was of 271.5 kg N ha(-1). An increase of 0.0745 cm tiller(-1) day(-1) for 1 kg of N ha(-1) applied to height of 15 cm of residue was observed. Nitrogen fertilization contributes positively to growth and development of rates of appearance and leaf extension. The management of pasture of Brachiaria brizantha cv. Marandu with 5 cm of residue and fertilization with 100 kg N ha(-1) provided better answer morphogenic traits.

Application of reverse Monte Carlo simulations to diatomic molecules. Part 1. Noncomplete radial distribution functions

The reverse Monte Carlo (RMC) method generates sets of points in space which yield radial distribution functions (RDFS) that approximate those of the system of interest. Such sets of configurations should, in principle, be sufficient to determine the structural properties of the system. In this work we apply the RMC technique to fluids of hard diatomic molecules. The experimental RDFs of the hard-dimer fluid were generated by the conventional MC method and used as input in the RMC simulations. Our results indicate that the RMC method is only satisfactory in determining the local structure of the fluid studied by means of only mono-variable RDF. Also we suggest that the use of multi-variable RDFs would improve the technique significantly. However, the accuracy of the method turned out to be very sensitive to the variance of the input experimental RDF. © 1995.

Direct retrospective comparison of adalimumab and infliximab in preventing early postoperative endoscopic recurrence after ileocaecal resection for crohn's disease: results from the MULTIPER database

Both adalimumab [ADA] and infliximab [IFX] seem to be effective in the prevention of early postoperative endoscopic recurrence [EPER] after ileocaecal resection in Crohn's disease [CD] patients. There is lack of data with direct comparison between the two agents in the postoperative scenario. The aim of this study was to compare the rates of EPER in patients treated with ADA and IFX after ileocaecal resection for CD. This was a multicentre retrospective analysis of EPER rates in CD patients after ileocaecal resections, from seven referral centres in three countries. Endoscopic recurrence was defined as Rutgeerts' score ≥ i2. The patients were allocated according to treatment to two groups: ADA or IFX. The EPER rates were compared between the two treatment groups. Among the 168 patients included in the database, 96 received anti-tumour necrosis factor [TNF] agents after resection [37 in the ADA and 59 in the IFX groups] and were included in this comparative study. The groups were comparable in all baseline characteristics, mainly age, gender, previous resections, perianal CD, and mono or combination therapy. EPER was identified in 9/37 [24.32%] in the ADA group vs 16/59 [27.12%] in the IFX group [p = 0.815]. In this retrospective direct comparison between ADA and IFX therapy after ileocaecal resection, there was no significant difference between the two anti-TNF agents in terms of EPER rates. However, prospective randomised studies are needed to confirm these data and better define the role of each agent in the prevention of EPER.

Organização de DNAs microssatélites nos cromossomos do gafanhoto Abracris flavolineata, com ênfase em cromossomos supranumerários

Com o propósito de se obter um conhecimento aprofundado sobre DNAs repetitivos e sua organização nos cromossomos de gafanhotos, nós utilizamos a técnica citogenética de Hibridização in situ fluorescente (FISH) para o mapeamento da distribuição de dezesseis sequências de microssatélites, incluindo mono-, di-, tri- e tetra-nucleotídeos, nos cromossomos da espécie Abracris flavolineata (Acrididae), que comporta um cromossomo B (supranumerário). A FISH (Hibridização in situ fluorescente) revelou pelo menos dois padrões distintos: (i) sinais exclusivamente espalhados, e (ii) sinais espalhados e específicos, formando blocos evidentes. O enriquecimento foi observado em ambas áreas de eucromatina e heterocromatina e também apenas o motivo (C)30 apresentou ausência na heterocromatina. Os cromossomos A e B se apresentaram enriquecidos com todos os elementos mapeados, sendo observado para o cromossomo a presença de blocos mais distintivos para (GA)15 e (GAG)10. Para o complemento A blocos distintos foram observados para (A)30, (CA)15, (CG)15, (GA)15, (CAC)10, (CAA)10, (CGG)10, (GAA)10, (GAC)10 e (GATA)8. Estes resultados revelaram um intenso espalhamento dos microssatélites no genoma de Abracris flavolineata independentemente de enriquecimento de A+T ou G+C de cada uma das sequências. Os dados indicam que os microssatélites compõem o cromossomo B e que poderiam estar envolvidos na evolução deste elemento na espécie em estudo, embora nenhuma relação específica com qualquer cromossomo A tenha sido observado para discutir sobre sua origem. A análise sistemática apresentada neste trabalho contribui para o conhecimento sobre DNAs repetitivos e sua organização nos cromossomos dos gafanhotos, incluindo os cromossomos B

Compostos de paládio(II) contendo ligantes sulfurados: síntese, caracterização e investigação da atividade biológica

This work deals with the synthesis, spectroscopic characterization of mono and polynuclear Pd(II) compounds obtained from the reaction between [PdCl2(MeCN)2] precursor and imidazolidine-2-thione (L1) and benzimidazoline-2-thione (L2). The interaction between [PdCl2(MeCN)2] and imidazolidine-2-thione, in the 1:2 molar ratio, using MeOH as solvent, yielded compound [Pd2Cl4(L1)4]Cl2 (1) whereas the complex [Pd2Br4(L1)4]Br2 (2) was obtained from the reaction between 1 and Br- ions. Binuclear compounds of general formulae [Pd2(L2)4]X23/2 MeOH {X= Cl-(3), Br-(4)} were synthesized using benzimidazoline-2-thione as ligand, employing the same procedure used in the synthesis of 1 and 2, respectively. The new complexes 1-4 are crystalline, air stable and soluble in methanol and dmso. The compounds were characterized by elemental analysis, IR spectroscopy, ESI/MS mass spectrometry and thermogravimetry. Coordination of the ligands L1 and L2 via sulphur atom was evidenced by the shift of the CS band (~499 cm-1, 1 and 2; ~620 cm-1, 3 and 4) to lower frequencies in comparison with those found in the free ligands (510 cm-1, L1; 660 cm-1, L2), indicating the weakening of the CS bom after coordination. ESI/EM mass spectra (positive mode) of the complexes 1-4 allowed atribute the molecular formulae [Pd2X4(L1)4]X2 {X= Cl-(1), Br-(2)} and [Pd2(L2)4]X2 {X= Cl-(3), Br-(4)} by the appearance of the peaks at m/z 794,61 [(1) + MeOH]+, m/z 836,77 [(2) - 2H - L1]+, m/z 810 [(3) - 2Cl]+, m/z 810 [(4) - 2Br]+. The TG-DTA curves showed that the complexes 1 and 2 are thermally stable up to 212 and 169º C, respectively, and further decompose to metallic palladium at 527º C (1, obt. 28,46 %; calcd. 27,88%) and 895º C (2, obt. 22,85 %; calcd. 22,62%). Compounds 3 and 4 exhibited an initial mass loss of ~5% between 25 -146º C related to the release of metanol molecules. The complexes 3...Fujimura Leite.

Avaliação de polimorfismos genéticos na progressão da infecção de pacientes monoinfectados e coinfectados com os Vírus da Imunodeficiência Humana (HIV) e Vírus da Hepatite C (VHC)

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Avaliação Histológica e histomorfométrica do reparo ósseo em tíbias osteotomizadas de ratos (rattus novergicus albinus), submetidos a tratamento com ultrassom, frente à presença e ausência de carga

The response of bone metabolism is directly related to hormonal factors and mechanical stimuli that the bone is exposed. The ultrasonic energy on bone healing have been shown to be crucial for the stimulation and improvement in quality of newly formed tissue. The aim of this study was to analyze the action of low intensity ultrasound on bone healing of tibial osteotomy in rats subjected to tail suspension, through histological analysis and histomorphometry. Eighteen Rattus norvegicus albinos, Wistar, adults were divided into three groups, arranged as follows: G1 (n = 6), who remained free for a period of 15 days, G2 (n = 5), suspended by the tail for a period of 15 days and G3 (n = 7), suspended by the tail for a period of 36 days. In all three groups, both tibias were subjected to mono-cortical bone injury 4X2 mm in the medial region of the diaphysis, and the left limb was used as control and the right limb undergoing treatment with ultrasound (U.S.). The right tibia was treated with pulsed ultrasound at a frequency of 1.5 MHz, duty cycle 1:4, 30mW/cm2, for 12 sessions of 20 minutes each. Samples of tibia were subjected to histological analysis, blindly, with light microscopy and histomorphometric analysis by specific software Image-Pro 6.1. The average percentage of new bone formation were subjected to analysis of variance in subdivided parcels and multiple comparison test "Student-Newman-Keuls (SNK), with a significance level of 5%. The average values and standard deviations of the percentage of newly formed bone for the groups showed the least amount of bone repair G1t (13.62% ± 4.88%) - G1c (8.68% ± 4.16%) compared G2t groups (27.17% ± 11.36%) - G2c (10.10% ± 7.90%) and G3t (23.19% ± 5.61%) - G3c (15.74% ± 7 08%). However, the mean values and standard deviations of the percentage of newly formed bone repair in the tibia treated G2t and G3t were significantly higher when compared to the repair of tibia in the control group (G2c and G3c). Consequently, we conclude that ultrasound has helped to accelerate bone repair in both the presence and absence of cargo.

Perfil de aptidão cardiorrespiratória em corredores jovens pela cinética do VO2 em testes progressivos e retangulares

Pós-graduação em Desenvolvimento Humano e Tecnologias - IBRC