Martinsville : report of the Illinois Low-Level Radioactive Waste Disposal Siting Commission on its inquiry into the Martinsville alternative site /

Includes bibliographical references.

Proposed site-selection criteria for a low-level radioactive waste disposal facility /

"August 16, 1995."

Site-selection criteria for a low-level radioactive waste disposal facility /

"December 19, 1996."

Statewide screening activities for Illinois' low-level radioactive waste (LLRW) disposal facility : final report to the Illinois Low-Level Radioactive Waste Task Group and the director, Illinois Department of Nuclear Safety /

"This report was prepared under a contract with the Illinois Dept. of Nuclear Safety (IDNS) in support of the Illinois Low-Level Radioactive Waste Task Group. Numerous staff members of the Illinois State Geological Survey (ISGS) and the Illinois State Water Survey (ISWS) contributed to this report, which was compiled under the general administrative direction of Bill Shilts and Derek Winstanley, Chiefs of the ISGS and ISWS, respectively."--P. iv.

Summary of responses to issues raised by public comment in reference to Site selection criteria for a low-level radioactive waste disposal facility /

"December 19, 1996."

An historical account of the great level of the Fens, called Bedford level, and other fens, marshes and low-lands in this kingdom, and other places; with references to Leland's Itinerary, Dugdale's History of imbanking and draining, and others of the most approved authority.

Goldsmiths'-Kress no. 15577.

Operator, organizational, direct support, general support, and depot maintenance manual : device, low level signaling, TT-523/GGC (NSN 5815-00-937-6146) and TT-523A/GGC (NSN 5815-00-999-3048).

"October 1967."

Organizational maintenance manual (including repair parts and special tools lists) : 2.75-inch low spin, folding fin aircraft rockets, 66-mm light antitank weapon systems, 3.5-inch rockets, and M3A2E1 rocket motor (JATO).

"June 1973."

Direct support and general support maintenance manual (including repair parts and special tools list) for 2.75-inch low spin, folding fin aircraft rockets, 66-mm light antitank weapon systems, 3.5-inch rockets and M3A2E1 rocket motor (JATO).

"August 1974."

Organizational maintenance manual (including repair parts and special tools lists) : 2.75-inch low spin, folding fin aircraft rockets, 66-mm light antitank weapon systems, 3.5-inch rockets, and M3A2E1 rocket motor (JATO).

"June 1973."

Operator, organizational, direct support, general support, and depot maintenance manual : device, low level signaling, TT-523/GGC (NSN 5815-00-937-6146) and TT-523A/GGC (NSN 5815-00-999-3048).

"October 1967."

Quaternary geology of the Martinsville alternative site, Clark County, Illinois : a proposed low level radioactive waste disposal site /

Includes bibliographical references (p. 81-83).

Piloted flight simulation study of low-level wind shear : phase 2 : all weather landing systems, engineering services support project, task 2 /

Includes bibliographical references.

Adverse Health Effects of Chronic Exposure to Low-Level Cadmium in Foodstuffs and Cigarette Smoke

Cadmium is a cumulative nephrotoxicant that is absorbed into the body from dietary sources and cigarette smoking. The levels of Cd in organs such as liver and kidney cortex increase with age because of the lack of an active biochemical process for its elimination coupled with renal reabsorption. Recent research has provided evidence linking Cd-related kidney dysfunction and decreases in bone mineral density in nonoccupationally exposed populations who showed no signs of nutritional deficiency. This challenges the previous view that the concurrent kidney and bone damage seen in Japanese itai-itai disease patients was the result of Cd toxicity in combination with nutritional deficiencies, notably, of zinc and calcium. Further, such Cd-linked bone and kidney toxicities were observed in people whose dietary Cd intakes were well within the provisional tolerable weekly intake (PTWI) set by the Joint Food and Agriculture Organization/World Health Organization Expert Committee on Food Additives of 1 mug/kg body weight/day or 70 mug/day. This evidence points to the much-needed revision of the current PTWI for Cd. Also, evidence for the carcinogenic risk of chronic Cd exposure is accumulating and Cd effects on reproductive outcomes have begun to emerge.

Effects of chronic exposure to low-level cadmium on renal tubular function and CYP2A6-mediated coumarin metabolism in healthy human subjects

Relationships between cadmium (Cd) body burden, kidney function and coumarin metabolism were investigated using two groups of 197 and 200 healthy Thais with men and women in nearly equal numbers. A mean age of one group was 30.5 years and it was 39.3 years for the other group. Of 397, 20 subjects (5%) excreted urine Cd between 1.4 mug/g and 3.8 mug/g creatinine and these subjects faced 10-15% increase in the probability of having abnormal urinary excretion of N-acetyl-beta-D-glucosaminidase (NAG-uria). The prevalence of NAG-uria varied with Cd body burden in a dose-dependent manner (chi(2) = 22, P < 0.008). Also NAG-nuria was one of the three kidney effect markers tested that showed the greatest strength of correlation with urine Cd in both men and women (r = 0.48 P < 0.001). In addition, urine Cd excretion of men and women showed a positive correlation (r = 0.46 to 0.54. P < 0.001) with urine 7-hydroxycoumarin (7-OHC) excretion which was used as a marker of liver cytochrome P450 2A6 (CYP2A6) enzyme activity. Urinary CA excretion accounted for 25% of the total variation in urine 7-OHC excretion (P < 0.001). These data suggest that Cd may increase the expression of CYP2A6 in liver, resulting in enhanced coumarin metabolism in subjects with high Cd body burden. (C) 2003 Elsevier Ireland Ltd. All rights reserved.