984 resultados para Hager, Giuseppe, 1757-1819


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v. 1. ano de 1808 a 1811. 1836 -- v. 2. ano de 1812 a 1818 -- v. 3. ano de 1819 a 1822. 1837 -- v. 4 ano de 1823 a 1824. 1838 -- v. 5. ano a 1826. 1838 -- v. 6. ano de 1827 a 1828. 1841 -- v. 7. ano de 1829 a 1831 e índice. 1844.

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As Voyages... são estudos completos, abrangendo todos os aspectos das regiões percorridas; servem de subsídio ao estudo das condições de vida no Brasil no século passado. "Fonte primordial de informações sobre os prédios coloniais do Rio de Janeiro, Minas Gerais, São Paulo, Santa Catarina e Goiás. Poucas obras no gênero atingem o valor de Saint-Hilarire. São clássicas e indispensáveis para o estudo do sul do Brasil, antes da Independência" segundo Borba de Moraes.

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A Bibliografia da Impressão Régia do Rio de Janeiro diz: "Terminada a publicação dos Estudos do comum... (1819-1820), José da Silva Lisboa planejou publicar uma coletânia dos escritos do Padre Vieira como apêndice à obra...'

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A bibliografia da Impressão Régia do Rio de Janeiro diz: "Terminada a publicação dos EStudos do bem comum... (1819-1820), José da Silva Lisboa planejou publicar uma coletânea dos esccritos do Padre Vieira como apêndice à obra..."

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Aborda, sob o aspecto econômico, temas relacionados com a morte.

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Contém uma relação de todos os deputados brasileiros desde as cortes portuguesas e a constituinte até a 14ª legislatura ordinária.

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A primeira guerra mundial aconteceu entre 1757 e 1763 e é a única guerra que tem diversos nomes nos países que atingiu. Envolveu a Prússia, de Frederico II, o Império Austro-Húngaro, a Rússia, a França, a Espanha, a Inglaterra e o seu tradicional aliado, Portugal.

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Background: The World Gastroenterology Organization recommends developing national guidelines for the diagnosis of Celiac Disease (CD): hence a profile of the diagnosis of CD in each country is required. We aim to describe a cross-sectional picture of the clinical features and diagnostic facilities in 16 countries of the Mediterranean basin. Since a new ESPGHAN diagnostic protocol was recently published, our secondary aim is to estimate how many cases in the same area could be identified without a small intestinal biopsy. Methods: By a stratified cross-sectional retrospective study design, we examined clinical, histological and laboratory data from 749 consecutive unselected CD children diagnosed by national referral centers. Results: The vast majority of cases were diagnosed before the age of 10 (median: 5 years), affected by diarrhea, weight loss and food refusal, as expected. Only 59 cases (7.8%) did not suffer of major complaints. Tissue transglutaminase (tTG) assay was available, but one-third of centers reported financial constraints in the regular purchase of the assay kits. 252 cases (33.6%) showed tTG values over 10 times the local normal limit. Endomysial antibodies and HLA typing were routinely available in only half of the centers. CD was mainly diagnosed from small intestinal biopsy, available in all centers. Based on these data, only 154/749 cases (20.5%) would have qualified for a diagnosis of CD without a small intestinal biopsy, according to the new ESPGHAN protocol. Conclusions: This cross-sectional study of CD in the Mediterranean referral centers offers a puzzling picture of the capacities to deal with the emerging epidemic of CD in the area, giving a substantive support to the World Gastroenterology Organization guidelines.

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Background: The presence of EGFR kinase domain mutations in a subset of NSCLC patients correlates with the response to treatment with the EGFR tyrosine kinase inhibitors gefitinib and erlotinib. Although most EGFR mutations detected are short deletions in exon 19 or the L858R point mutation in exon 21, more than 75 different EGFR kinase domain residues have been reported to be altered in NSCLC patients. The phenotypical consequences of different EGFR mutations may vary dramatically, but the majority of uncommon EGFR mutations have never been functionally evaluated. Results: We demonstrate that the relative kinase activity and erlotinib sensitivity of different EGFR mutants can be readily evaluated using transfection of an YFP-tagged fragment of the EGFR intracellular domain (YFP-EGFR-ICD), followed by immunofluorescence microscopy analysis. Using this assay, we show that the exon 20 insertions Ins770SVD and Ins774HV confer increased kinase activity, but no erlotinib sensitivity. We also show that, in contrast to the common L858R mutation, the uncommon exon 21 point mutations P848L and A859T appear to behave like functionally silent polymorphisms. Conclusion: The ability to rapidly obtain functional information on EGFR variants of unknown relevance using the YFP-EGFR-ICD assay might prove important in the future for the management of NSCLC patients bearing uncommon EGFR mutations. In addition, our assay may be used to determine the response of resistant EGFR mutants to novel second-generation TKIs.

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The control role of the relative phase between the probe and driving fields on gain, dispersion and populations in an open V-type three-level system with spontaneously generated coherence is studied. The result shows that by adjusting the value of the relative phase, the transformation between lasing with inversion and lasing without inversion (LWI) can be realized and high dispersion (refractive index) without absorption can be obtained. The shape and value range of the dispersion curve are similar to those of the gain curve, and this similarity is closely related to the relative phase. The effects of the atomic exit and injection rates and the incoherent pump rate on the control role of the relative phase are also analysed. It is found easier to get LWI by adjusting the value of the relative phase using the open system rather than the closed system, and using an incoherent pump rather than without using the incoherent pump. Moreover the open system can give a larger LWI gain than the closed system.