994 resultados para Fluoreto de sódio, administração
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Fundao de Amparo Pesquisa do Estado de So Paulo (FAPESP)
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Fundao de Amparo Pesquisa do Estado de So Paulo (FAPESP)
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Objectives: Epidemiological studies have shown a relationship between long-term use of proton pump inhibitors and bone metabolism. However, this relationship has not yet become established. The aim of the present study was to analyze the mechanical properties and bone mineral density (BMD) of rats that were subjected to long-term omeprazole use. Methods: Fifty wistar rats weighing between 200 and 240 g were divided equally into five groups: OMP300 (omeprazole intake at a dose of 300 moL/kg/day); OMP200 (200 moL/ kg/day); OMP40 (40 moL/kg/day); OMP10 (10 moL/kg/day); and Cont (control group; intake of dilution vehicle). The solutions were administered for 90 consecutive days. After the rats had been sacrificed, their BMD, the mechanical properties of the dissected femurs and their serum Ca++ levels were analyzed. Results: The BMD of the OMP300 group was lower than that of the controls (p = 0.006). There was no difference in comparing the OMP200, OMP40 and OMP10 groups with the controls. The maximum strength and rigidity of the femur did not differ in the experimental groups in comparison with the controls. The OMP300 group had a statistically lower serum Ca++ concentration than that of the controls (p = 0.049), but the other groups did not show any difference in relation to the controls. Conclusion: Daily intake of 300moL/kg/day of omeprazole decreased the BMD of the femur, but without changes to the rigidity and strength of the femur in adult rats. 2
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Foi atendido no Hospital Veterinrio Luiz Quintiliano de Oliveira, o felino Nick, SRD, de quatro meses de idade, pesando 700 gramas, com histrico de trauma por arranhadura em bulbo ocular esquerdo. Ao exame fsico especfico, evidenciou-se lcera profunda e prolapso de ris, sendo ento indicada a enucleao. Ao exame fsico geral, observou-se freqncia cardaca (FC) de 160 batimentos.min-1, frequncia respiratria (f) de 80 movimentos.min-1, tempo de preenchimento capilar menor do que dois segundos, temperatura retal (TR) de 39,2oC e mucosas normocoradas. Como medicao pr-anestsica, empregou-se acepromazina (0,04 mg.kg-1) e metadona (0,3 mg.kg-1), administradas pela via intramuscular. A veia femoral esquerda foi cateterizada com cateter 24G para administração de Ringer com Lactato de sdio (10 mL.kg-1.h- 1 ). A induo foi realizada por mscara facial tendo-se como agente o isofluorano em fluxo diluente de 100 mL.kg-1.min-1 de oxignio a 100%, seguida de intubao orotraqueal com sonda n o 2,5 sem cuff. Seguiu-se a manuteno anestsica com a mesma mistura da induo, administrada por meio de circuito anestsico sem reinalao de gases, do tipo Baraka, mantendose o paciente sob ventilao assistida. Ato contnuo, realizou-se a tcnica anestsica peribulbar de puno nica inferior, utilizando-se lidocana 2% com vasoconstritor (3mg.kg-1) associada a bupivacana 0,5% sem vasoconstritor (0,8mg.kg-1), perfazendo um volume total de 0,3ml.kg-1 . Uma agulha 13x4,5 foi introduzida em todo o seu comprimento com o bisel voltado para a rbita, no tero lateral do frnice conjuntival inferior da rbita esquerda, administrando-se a associao dos agentes anestsicos locais, seguida de compresso manual da rea para facilitar a difuso dos mesmos. Durante o procedimento anestsico, realizou-se a monitorao da FC, f, presso arterial sistlica (PAS), TR e saturao perifrica da hemoglobina (SpO2). O tempo total de anestesia e cirurgia foi de 30 e 20 minutos, respectivamente, e a SpO2, concentrao de isofluorano e TR mantiveram-se em 991%, 1,70,8% e 37,41,5oC, respectivamente. O plano anestsico manteve-se estvel, sem a necessidade de resgate analgsico. No houve a ocorrncia de reflexo culo-cardaco (ROC) frente manipulao do nervo ptico, o que pode ser atribuda provavelmente ao bloqueio peribulbar. A anestesia regional frequentemente empregada para cirurgias oftlmicas em humanos, como a facoemulsificao, sendo que o manejo anestsico pode contribuir para o sucesso do procedimento. Pode-se concluir que, tambm na espcie felina, o bloqueio peribulbar pode ser uma boa alternativa para a realizao de protocolos de anestesia balanceada para procedimentos oftlmicos.
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Introduo: a eliminao de bactrias dos canais radiculares essencial no tratamento endodntico de dentes com polpas necrosadas, desde que bactrias no s causam, mas tambm mantm, as leses periapicais. Objetivo: analisar in vivo a influncia de solues irrigantes (NaOCl 1%, NaOCl 2,5%, soluo salina estril 0,9%) no tratamento de dentes de ces com leso periapical crnica em sesso nica. Mtodos: quarenta canais radiculares de trs ces da raa Beagle permaneceram expostos cavidade bucal para permitir a contaminao e a formao de leses periapicais crnicas. Em seguida, os canais radiculares foram preparados biomecanicamente. Durante a instrumentao, trs solues irrigantes foram utilizadas: G1 NaOCl 2,5%; G2 NaOCl 1%; G3 soluo salina estril 0,9%. O grupo controle (G4) no recebeu tratamento nem selamento coronrio. Os canais radiculares foram obturados com cones de guta-percha e Sealapex. As aberturas coronrias foram seladas com IRM e amlgama. Aps 6 meses, os animais foram sacrificados e blocos de tecido processados histologicamente para serem corados com hematoxilina e eosina, ou Brown e Brenn. Resultados: no houve diferena histolgica significativa entre a utilizao de hipoclorito de sdio a 1% ou 2,5% (p>0,05), mas houve entre eles e a soluo salina estril a 0,9% (p<0,05). Concluso: concluiu-se que o uso de solues irrigantes com potencial antibacteriano (hipoclorito de sdio a 1% e 2,5%) proveu condies mais favorveis ao processo de reparo.
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Sodium cyclamate contents in the widely consumed low calorie soft drinks were determined. Low calorie soft drinks made from cola, guarana, orange, lemon and grape were analyzed following the technique described by Sjrberg and Alanko (1987), with some modifications. The methodology recovery assays were carried out at three spiked levels, and the average recovery of 92.5% and 110.3% were found in cola and guarana, respectively; and the relative standard deviation was of 3.7%. The average sodium cyclamate contents ranged from 27.1 1.1 (cola A) to 127.3 1.5 mg.100 mL-1 (lemon B), indicating that the acceptable daily intake of the sweetener can be easily exceeded after drinking low calorie beverages. All of the analyzed low calorie soft drinks showed sodium cyclamate contents higher than those stated on the label, ranging from 12.9% (cola A) to 19.0% (lemon B). Among 18 low calorie soft drinks analyzed, only four showed the average sodium cyclamate contents in accordance with the maximum limit permitted by Brazilian legislation, that is 40 mg.100 mL-1 of beverage; and in other samples the sweetener exceeded ranging from 74.8% (orange) to 218.3% (lemon B) above of the limit permitted.
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Ps-graduao em Enfermagem - FMB
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Coordenao de Aperfeioamento de Pessoal de Nvel Superior (CAPES)
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Fundao de Amparo Pesquisa do Estado de So Paulo (FAPESP)
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Coordenao de Aperfeioamento de Pessoal de Nvel Superior (CAPES)
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Harassment at work is not a recent phenomenon. However, have been widened-discussions on the question, its causes and factors organizational intimately linked to it. This article brings to light the concept of harassment moral the scope of work and makes reflections on the management models and leadership, and how to trigger this process, at the same time, it questions the alternatives to minimize the impact of this problem through a conscious and participative management, by creating and of spaces and educational policies, valuing if the worker and building an environment ethic of work. In addition, propose alternatives of prevention of harassment, by means of leadership with the contribution of psychologist organizational and work.
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This research leads to a meta-analysis of scientific production in energy efficiency in industrial sectors, recorded in ten (10) leading journals in Administration and Engineering Production in Brazil, between 2001 and 2011. To this end, this scholarship was examined based on the following parameters: a) the total contribution and journal articles, b) methods used in studies, and c) the theoretical gaps to exploit. The diagnosis is that one infers: academic work in energy efficiency industries accounted for only twenty-nine (29) published articles, and only eight (8) have energy efficiency as a central theme of the work. Although the results still showed a rising trend in the number of publications since the last five (5) years analyzed showed 65.5% of all published files relating to energy efficiency. It contributes, therefore, the systematization of the academic production in the area of energy efficiency and business subsidies are provided for this field of research in Brazil.
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Conselho Nacional de Desenvolvimento Cientfico e Tecnolgico (CNPq)
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Fundao de Amparo Pesquisa do Estado de So Paulo (FAPESP)
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Coordenao de Aperfeioamento de Pessoal de Nvel Superior (CAPES)
