Síntese e avaliação biológica de novos derivados anti-inflamatórios esteroides

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Redes de apoio às famílias de dependentes de álcool e outras drogas: uma interface com as políticas públicas intersetoriais

Pós-graduação em Serviço Social - FCHS

Estudo dos compostos voláteis da decomposição térmica dos anti-helmínticos Albendazol e Mebendazol

The albendazole and mebendazole drugs are benzimidazole derivatives and belong to the anthelmintic class. These drugs are particularly recommended for the treatment against worms present in the gastrointestinal tract of animals and humans, by acting directly on the worm metabolism. The need for thermally study drugs is related to all the parameters that these analyzes include: presence or absence of polymorphs, possible changes in the crystallinity of the drugs, as well as the quality control during the manufacturing process thereof. In this study the thermal behavior of anthelmintic albendazole and commercial mebendazole and its recrystallisation in organic solvents, such as acetic acid and formic acid in dimethylformamide to mebendazole, and albendazole were studied using TG-DSC techniques, TG-FTIR, FTIR and XRD. TG-DSC techniques were used so it could collect information about the thermal stability of the compounds steps for thermal decomposition process and also prove its melting temperature. For recrystallization of drugs in organic solvents, the TG-DSC curves were analyzed to compare and determine that the occurrence of polymorphs. The coupled TG-FTIR technique allowed the analysis of volatile products which were released during the thermal decomposition of the commercial mebendazole. The absorption spectroscopy in the infrared region was performed to mebendazole, and albendazole in order to show the difference in functional groups of both, comparing the spectra with commercial drugs and see if there was recrystallized changes in the absorption band where the drug was recrystallized or when heated. The diffraction technique by powder X-ray method was used for comparison of the crystal structures of commercial drugs and recrystallization in organic solvents to identify changes in crystallinity both, which might suggest the formation of polymorphs

Tecnologias virtuais e análise videográfica: o YouTube® como recurso de pesquisa para compreensão sobre a imagem do idoso brasileiro = Virtual technologies and videographic analysis : YouTube® as research resource for understanding about brazilian elderly imagem

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Obtenção e caracterização de nanopartículas lipídicas sólidas como sistema de transporte para ibuprofeno

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Tom e Vinícius na Alvorada: um prisma geográfico

This article has been generated by the interface between geography and music. Methodologically, we have used a multidisciplinary bibliography that contemplates cultural geography, history, music, linguistics, literature, anthropology, for we understand that, for the understanding of a polysemous code, as it is in music, we need a diversity of looks. Our main document for an analysis of the construction of Brasília is the “Sinfonia da Alvorada” (Symphony of the Dawn), composed by Antônio Carlos Jobim and Vinícius de Moraes. Here, we attempt mainly to do a textual analysis of the work under an external perspective of the symphonic work, we mean, analyzing more its semantics (considering the product between interlocution and interpretation), and less its instrumental aesthetics, although the latter is also present. Finally, we attempt to understand the connection that exists between the actors and the spaces which are metamorphosing along with the construction of the city and which puts into evidence the idea of social circularity, proposed by the “Sinfonia da Alvorada”. This piece captures social and cultural elements related to the construction of Brasília and repositions and rearranges it through the execution of the music, in such a way that this arrangement can provide a change in the senses which are constructed from the urban experience in Brasília.