990 resultados para Dengue - Paranavaí (PR) - 1999


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[Mazarinade. 1649]

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The people involved in opening Harrison Hall.

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Men's baseball team after winning the 1999 national championships.

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Harrison Hall holds the new Student Health Centre and Athletic Therapy Clinic. The centre provides the University's Health Services Department with a greater amount of space for students and staff, and the building is designed to make treatment more comfortable and efficient. The centre includes four examination rooms as part of the increased space. It is named after Bernard Harrison, a former Brock physics demonstrator who has donated over $1 million to the University.

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The building, which is attached to the Mackenzie Chown complex, holds facilities for Brock's Cool Climate Oenology and Viticulture Institute. The Institute, which studies grape growing and wine production, is the only one of its kind in Canada, and only the third of its kind in North America. It includes specialized research laboratories, a climate-controlled wine cellar, a wine library, and a museum. The building is named after a Niagara winery, Inniskillin Wines.

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Arabidopsis is a model plant used to study disease resistance; Solanum tuberosum or potato is a crop species. Both plants possess inducible defense mechanisms that are deployed upon recognition of pathogen invasion. Transcriptional reprogramming is crucial to the activation of defense responses. The Pathogenesis-Related (PR) genes are activated in these defense programs. Expression of Arabidopsis PR-l and potato PR-10a serve as markers for the deployment of defense responses in these plants. PR-l expression indicates induction of systemic acquired resistance (SAR). Activation of SAR requires accumulation of salicylic acid (SA), in addition to the interaction of the non-expressor of pathogenesis-related genes I (NPRI), with the TGA transcription factors. The PR-10a is activated in response to pathogen invasion, wounding and elicitor treatment. PR-10a induction requires recruitment of the Whirly I (Whyl) activator to the promoter. This locus is also negatively regulated by the silencer element binding factor (SEBF). We established that both the PR-l and PR-10a are occupied by repressors under non-inducing conditions. TGA2 was found to be a constitutive resident and repressor of PR-l, which mediates repression by forming an oligomeric complex on the promoter. The DNA-binding activity of this oligomer required the TGA2 N-terminus (NT). Under resting conditions we determined that the PR-10a is bound by a repressosome containing SEBF and curiously the activator Pto interacting protein 4 (Pti4). In the context of this repressosome, SEBF is responsible for PR-10a binding, yet rWe also showed that PR-l and PR-10a are activated by different means. In PR-l activation the NPRI NT domain alleviates TGA2-mediated repression by interacting with the TGA2 NT. TGA2 remains at the PR-l but adopts a dimeric conformation and forms an enhanceosome with NPRl. In contrast, the PR-10a is activated by evicting the repressosome and recruiting Why! to the promoter. These results advance our understanding of the mechanisms regulating PR-l and PR-10a expression under resting and inducing conditions. This study also revealed that the means of regulation for related genes can differ greatly between model and crop s

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On spine : The Grand Lodge of Canada in the Province of Ontario.

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Annual Convocation proceedings for the year 1999. The title varies slightly and convocation is held at different cities or towns in Canada. One hundred and forty-first annual convocation.

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A letter from the Honourable Sergio Marchi, Minister for International Trade to Donald Ziraldo to discuss the status of the EU Commission and wine issues. He commits to "opening markets for Canadian wine exports to the European Union". The letter is dated 23 April, 1999.