Avaliação da toxicidade da vinhaça tratada quimicamente utilizando Oreochromis niloticus (Perciformes: Cichlidae) como organismo teste

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Efeitos de perfurações artificiais no processo de decomposição em Sus Scrofa (L.) e confecção de uma check-list da entomofauna de Diptera visitante, durante inverno e verão, na região sudeste

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Estudo da adsorção de níquel (II) e zinco (II) em soluções aquosas por lama vermelha natural e ativada: influência do PH, isotermas, cinética e termodinâmica

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Efeito da adição de açúcares e do processo de envelhecimento na qualidade sensorial de amostras de cachaça obtidas tradicionalmente e por redestilação

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Avaliação comparativa do processo de incorporação de bloco sintético bifásico, e do osso autógeno: estudo histológico, histométrico e imunoistoquímico em coelhos

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Delayed tooth replantation after treatment of necrotic periodontal ligament with citric acid

Objective: to evaluated the effect of treating root-adhered necrotic periodontal ligament (PDL) with citric acid on the healing process in delayed rat tooth replantation. Material and Methods: Forty Wistar rats, assigned to 4 groups (n=10), had their upper right incisor extracted and kept dry on a workbench. For Group I (control), the teeth were replanted after a 5 min extra-alveolar time. For the other groups, replantation was hydroxide-based paste and the teeth were replanted with no root surface treatment. In Group III, the teeth were immersed in citric acid (pH 1) for replanted. In Group IV, instead of the immersion, the roots were scrubbed with gauze soaked in citric acid and the teeth were replanted. The animals difference (p > 0.05) was found among the groups regarding the areas difference (p < 0.05) between the control group and Group IV regarding ankylosis. The control group showed the least replacement resorption percent means compared to the other groups (p < 0.05). The root structure was more affected by replacement resorption and ankylosis in Group IV statistically (p > 0.05). Conclusion: the treatment of root surface-adhered necrotic periodontal ligament with citric acid was not able to prevent the delayed rat tooth replantation.

Delayed tooth repalantetion after treatment of necrotic periodontal ligament with citric acid

Objective: to evaluated the effect of treating root-adhered necrotic periodontal ligament (PDL) with citric acid on the healing process in delayed rat tooth replantation. Material and Methods: Forty Wistar rats, assigned to 4 groups (n=10), had their upper right incisor extracted and kept dry on a workbench. For Group I (control), the teeth were replanted after a 5 min extra-alveolar time. For the other groups, replantation was done after 60 min. In Group II, the root canals were filled with a calcium hydroxide-based paste and the teeth were replanted with no root surface treatment. In Group III, the teeth were immersed in citric acid (pH 1) for 3 min, the canals were filled with calcium hydroxide and the teeth were replanted. In Group IV, instead of the immersion, the roots were scrubbed with gauze soaked in citric acid and the teeth were replanted. The animals were sacrificed 60 days postoperatively. Results: Regarding replacement resorption, there was statistically significant difference (p < 0.05) between the control group and the other three groups. No statistically significant difference (p > 0.05) was found among the groups regarding the areas of inflammatory resorption. There was also a statistically significant difference (p < 0.05) between the control group and Group IV regarding ankylosis. The control group showed the least replacement resorption percent means compared to the other groups (p < 0.05). The root structure was more affected by replacement resorption and ankylosis in Group IV compared to the Groups II and III, but this difference was not significant statistically (p > 0.05). Conclusion: the treatment of root surface-adhered necrotic periodontal ligament with citric acid was not able to prevent the occurrence of ankylosis, root resorption and inflammatory resorption in delayed rat tooth replantation.

Ozônioterapia no controle da infecção em cirurgia oral

The objective of the literature review showing their main biological properties involved in the tissue repair process and its therapeutic potential in the prevention , control and treatment of infection in oral surgeries . To carry out this study , a search of the PubMed database . 13 articles that met the inclusion criteria were found . Antimicrobial properties , antiálgicas , anti-inflammatory , imunu - stimulants , oxygenation and neoangiogenesis were attributed to ozone in several studies . And indications such as the treatment of alveolitis , osteomyelitis , osteonecrosis , wound healing in skin and mucosa and antisepsis been suggested. However , many of its effects have not been well understood. The doses and concentrations for their use are not standardized . Studies to establish doses and periods of administration are still needed for increasingly traumatic and biologically effective therapies are found to practice dentistry .

Impacto do controle glicêmico sobre as complicações associadas ao diabetes mellitus na osseointegração

The increased prevalence of diabetic individuals has become a public health problem. Diabetes Mellitus is a metabolic disorder characterized by an increase in plasma glucose levels. It impairs the physiological equilibrium in utilization of carbohydrate by tissues. The persistent hyperglycemia can produce deleterious effects on bone formation due the microvascular complication. The present paper reviews the bibliography linking the impact of glycemic control at complications associated at diabetes mellitus on osseointegration. In experimental models of diabetes it was observed a reduced level of bone-implant contact. This failure can be reduced by means of hyperglycemia control. Also, several studies point the beneficial effect of coated implant on osseointegration process. It is necessary to take special care into account for the placement of implants in diabetic patient and improve the percentages of implant survival. A rigorous control of plasma glycaemia, together with other measures, like as absence of chronic complications, good oral hygiene and regular medical follow-up has been related to rising the percentages of successful in diabetic patients.

Efeito de diferentes gomas de mascar sobre o pH salivar de crianças

Objective: To evaluate the effect of different chewing gum brands on the salivary pH of children with primary dentition. Method: Forty children were selected and assigned to four groups: control (no chewing gum); sugarless chewing gum; chewing gum with casein phosphopeptide-amorphous calcium phosphate; and chewing gum with xylitol. The first saliva collection was made after supervised tooth brushing for stabilization of the oral pH. Next, all children were instructed to drink slowly 100 mL of a cola-based soft drink (Coca-Cola®) and a new saliva collection was made 10 min later. Then, each group chewed on the chewing gum for 5 min and discarded it after this time. Saliva was collected again at 5, 10 and 15 min intervals after start using the chewing gum. Measurement of salivary pH was made with colorimetric test papers and a digital pH-meter. Data were analyzed statistically by analysis of variance and Tukey’s test at a 5% significance level. Results: The use of chewing gums accelerated the increase of salivary pH to considerably alkaline levels after consumption of an acidic beverage, especially within the first minutes. The highest levels were obtained in the groups of children that used chewing gums containing xylitol and casein phosphopeptide-amorphous calcium phosphate. Conclusion: Children that used the chewing gums after ingestion of an acidic soft drink presented an increase in salivary pH, with the best results in the groups that used chewing gums containing casein phosphopeptide-amorphous calcium phosphate and xylitol.

Influência do hipoclorito de sódio no processo de reparo de dentes de cães tratados em sessão única

Introdução: a eliminação de bactérias dos canais radiculares é essencial no tratamento endodôntico de dentes com polpas necrosadas, desde que bactérias não só causam, mas também mantêm, as lesões periapicais. Objetivo: analisar in vivo a influência de soluções irrigantes (NaOCl 1%, NaOCl 2,5%, solução salina estéril 0,9%) no tratamento de dentes de cães com lesão periapical crônica em sessão única. Métodos: quarenta canais radiculares de três cães da raça Beagle permaneceram expostos à cavidade bucal para permitir a contaminação e a formação de lesões periapicais crônicas. Em seguida, os canais radiculares foram preparados biomecanicamente. Durante a instrumentação, três soluções irrigantes foram utilizadas: G1 – NaOCl 2,5%; G2 – NaOCl 1%; G3 – solução salina estéril 0,9%. O grupo controle (G4) não recebeu tratamento nem selamento coronário. Os canais radiculares foram obturados com cones de guta-percha e Sealapex. As aberturas coronárias foram seladas com IRM e amálgama. Após 6 meses, os animais foram sacrificados e blocos de tecido processados histologicamente para serem corados com hematoxilina e eosina, ou Brown e Brenn. Resultados: não houve diferença histológica significativa entre a utilização de hipoclorito de sódio a 1% ou 2,5% (p>0,05), mas houve entre eles e a solução salina estéril a 0,9% (p<0,05). Conclusão: concluiu-se que o uso de soluções irrigantes com potencial antibacteriano (hipoclorito de sódio a 1% e 2,5%) proveu condições mais favoráveis ao processo de reparo.

Controle do crescimento e da seleção folicular por fatores locais e sistêmicos na espécie bovina

The regulation of ovarian activity is an integrated process involving extraovarian signals and intrafollicular factors. In such process, gonadotropins have an important role, but not always crucial. The initiation of primordial follicle growth and the early stages of folliculogenesis can occur without gonadotropins, however FSH may affect the rate of preantral follicle growth. On the other hand, the antral follicle development from 1 to 4 mm in diameter is completely gonadotropin-dependent in bovine, and the alternation of dependency from FSH to LH may be part of the mechanism involved in follicular selection. Locally produced growth factors, such as the IGF system, work in association with gonadotropins throughout the follicular growth and can influence follicular selection. Thus, the integration of these extraovarian signals and intrafollicular factors seems to determine whether a follicle will continue to develop or go atretic. This review focuses on the interaction between gonadotropins and intrafollicular factors in follicular development and selection in cattle.

Avaliação do potencial biológico de extratos hidroetanólicos de Astronium sp incorporados ou não em sistemas nanoestruturados: in vitro e in vivo: in vitro e in vivo

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Processo de obtenção da enzima lacase por fungo marinho, enzima lacase e uso da mesma

A presente invenção está relacionada com a otimização das condições de cultivo para produção de lacase por um 5 fungo derivado de ambiente marinho. Tais condições permitiram a obtenção de quantidades significativas de lacase após a purificação (1.300 U/L) com atividade enzimática ótima em PH 3,0 e 60ºC e com peso molecular na faixa de 60 a 70 KDa. Nas condições de cultivo otimizadas a 10 enzima apresentou eficiente estabilidade frente a diferentes valores de pH e temperatura, com manutenção de 100% da estabilidade térmica após 1 h mesmo em temperatura de 62ºC, e da estabilidade frente a diferentes PHs após 48h, além da resistência a íons metálicos.

Micropartículas de goma gelana revestidas com filmes de amido resistente/pectina como estratégia para administração oral de insulina

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)