Sexual maturity of Eurytium limosum (say 1818) from a subtropical mangrove in Brazil

The size at onset of maturity of Eurytium limosum from a subtropical mangrove in Brazil was investigated. In this species, sexual maturity for males can be indicated by the allometric growth and gonopod length. For females, the morphological sexual maturity can only be externally verified through the relative quantity of setae along the abdominal margins and pleopods. Internally, gonad development was also examined. The size at which half of the population is physiologically mature was 11.6 mm of CW for females and 12.3 mm of CW for males. The values for the morphological and physiological maturity are very similar, indicating that the development of the secondary sexual characters is synchronized with the achievement of the physiological maturity for E. limosum.

Tissue-based proteomics reveals FXYD3, S100A11 and GSTM3 as novel markers for regional lymph node metastasis in colon cancer

Regional lymph node metastasis negatively affects prognosis in colon cancer patients. The molecular processes leading to regional lymph node metastasis are only partially understood and proteomic markers for metastasis are still scarce. Therefore, a tissue-based proteomic approach was undertaken for identifying proteins associated with regional lymph node metastasis. Two complementary tissue-based proteomic methods have been employed. MALDI imaging was used for identifying small proteins (≤25 kDa) in situ and label-free quantitative proteomics was used for identifying larger proteins. A tissue cohort comprising primary colon tumours without metastasis (UICC II, pN0, n = 21) and with lymph node metastasis (UICC III, pN2, n = 33) was analysed. Subsequent validation of identified proteins was done by immunohistochemical staining on an independent tissue cohort consisting of primary colon tumour specimens (n = 168). MALDI imaging yielded ten discriminating m/z species, and label-free quantitative proteomics 28 proteins. Two MALDI imaging-derived candidate proteins (FXYD3 and S100A11) and one from the label-free quantitative proteomics (GSTM3) were validated on the independent tissue cohort. All three markers correlated significantly with regional lymph node metastasis: FXYD3 (p = 0.0110), S100A11 (p = 0.0071), and GSTM3 (p = 0.0173). FXYD3 and S100A11 were more highly expressed in UICC II patient tumour tissues. GSTM3 was more highly expressed in UICC III patient tumour tissues. By our tissue-based proteomic approach, we could identify a large panel of proteins which are associated with regional lymph node metastasis and which have not been described so far. Here we show that novel markers for regional lymph metastasis can be identified by MALDI imaging or label-free quantitative proteomics and subsequently validated on an independent tissue cohort. Copyright © 2012 Pathological Society of Great Britain and Ireland. Published by John Wiley & Sons, Ltd.

Drought risk assessment as changes in the potential stand yield classes and potential forest production for Sitka spruce, Scots pine, and pedunculate oak over the next 80 years in the Great Britain

Probabilistic climate data have become available for the first time through the UK Climate Projections 2009, so that the risk of tree growth change can be quantified. We assess the drought risk spatially and temporally using drought probabilities and tree species vulnerabilities across Britain. We assessed the drought impact on the potential yield class of three major tree species (Picea sitchensis, Pinus sylvestris, and Quercus robur) which presently cover around 59% (400,700 ha) of state-managed forests, across lowland and upland sites. Here we show that drought impacts result mostly in reduced tree growth over the next 80 years when using b1, a1b and a1fi IPCC emissions scenarios. We found a maximum reduction of 94% but also a maximum increase of 56% in potential stand yield class in the 2080s from the baseline climate (1961-1990). Furthermore, potential production over the national forest estate for all three species in the 2080s may decrease due to drought by 42% in the lowlands and 32% in the uplands in comparison to the baseline climate. Our results reveal that potential tree growth and forest production on the national forest estate in Britain is likely to reduce, and indicate where and when adaptation measures are required. Moreover, this paper demonstrates the value of probabilistic climate projections for an important economic and environmental sector.

Account books of Thomas Cradock, 1786-1818 (inclusive)

Account books listing patients, medicines administered, and fees charged by Dr. Thomas Cradock (1752-1821), primarily in Maryland, from 1786 to 1818. In addition to recording names, Cradock occasionally noted demographic information, the patient's location, or their occupation: from 1813 to 1816, he treated Richard Gent, a free African-American man; in 1813, he attended to John Bell, who lived in the Foggy Bottom neighborhood of Washington, D.C. Cradock further noted if the patient was a slave and the name of his or her owner. He would also administer care on behalf of corporate entities, such as Powhatan Factory, which apparently refused him payment. He also sometimes included a diagnosis: in the cases of a Mr. Rowles and Mrs. Violet West, he administered unspecified medicines for gonorrhea at a cost of ten dollars. Commonly prescribed drugs included emetics, cathartics, and anodynes. Cradock also provided smallpox vaccination for his patients. He accepted both cash and payment-in-kind. Tipped into the first volume is an envelope containing a letter from the Medical and Chirurgical Faculty of Maryland to Mrs. Thomas Craddock in 1899 requesting a loan of portrait of Dr. Thomas Craddock [sic]. The three volumes also each contain an index to patient names.

A selected bibliography on municipal government in Great Britain,

Mode of access: Internet.

Poor laws--Ireland. Three reports

Disbound Original Held in Oak Street Library Facility.

The Law reports.

Edited by G.W. Hemming.

Songs of greater Britain : and other poems /

Mode of access: Internet.

British manufactures.

[Vols. 4-6] are called "Series IV-VI."

Coates's herd book.

Vols. - include the Shorthorn Society's Grading register for beef Shorthorn cattle; v. - include the society's Herd book of poll shorthorns.

A guide to the antiquities of Roman Britain in the Department of British and Mediæval Antiquities.

At head of title: British Museum.

Great Britain, an empire in transition,

"Selected bibliography": p. 339-342.

The Prince's ball. A brochure. From "Vanity fair."

A satirical poem on the Prince of Wales' visit to America in 1860.

Architectura canonica, or, Canons for church architecture : comprising observations thereon, plans, sketches, and illustrations ... with an epistle explanatory to Her Majesty's commissioners for building churches & chapels in Great Britain, Ireland and the colonies /

Mode of access: Internet.

Endgame for the West in Afghanistan? : explaining the decline in support for the war in Afghanistan in the United States, Great Britain, Canada, Australia, France and Germany /

Analyses of the War in Afghanistan frequently mention the declining or shaky domestic support for the conflict in the United States and among several U.S. allies. This paper dates the beginning of this decline back to the resurgence of the Taliban in 2005-06 and suggests that the deteriorating course of the war on the ground in Afghanistan itself along with mounting casualties is the key reason behind this drop in domestic support for the war.