969 resultados para Beauvoir, Simone de, 1908-1986 -- Criticism and interpretation


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Subaerial debris flows, with water contents ranging from as little as 10 wt% up to no more than about 25 wt% (Pierson, 1986; Pierson and Costa, 1987), are non-Newtonian fluids that move as fairly coherent masses with yield strength (owing to bulk densities and viscosity that are much greater than those of clear water), which enables them to suspend and transport large clasts. Their flow behavior is thought to be predominantly laminar, although the relative importance of laminar and turbulent flow has not been established and is debatable. They leave deposits (debrites) that are characteristically poorly sorted with large clasts in their middle portions and commonly protruding from their tops. Although generally ungraded or normally graded in their upper portions, many have centimeter- to decimeter-thick inversely graded basal zones (Arguden and Rodolfo, 1990, doi:10.1130/0016-7606(1990)102<0865:SADDBH>2.3.CO;2).

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Particles of red brown to yellow brown semiopaque oxides (RSO) dominate the insoluble residue fraction of the sediments at Site 597. Unlike the X-ray amorphous particles in the Bauer Deep sediments, these particles are composed of mainly goethite; the amount of X-ray amorphous ferric hydroxide and poorly crystalline ferromanganese oxyhydroxides is generally small relative to the amount of goethite. A qualitative goethite crystallinity index was established. The variations observed in the crystallinity of goethite with increasing depth and changes in lithology suggest that aging and long-term exposure to seawater in a high water/sediment regime influence and increase the rate of recrystallization of the Fe-oxyhydroxides of the RSO particles. The percentage of organic carbon is low in these sediments; it varies primarily between 0.2 and 0.4 wt.%. Phillipsite is present throughout the sediment column and is more concentrated in the youngest clay layer and in the oldest basal sediments.

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To be kept up to date with loose leaf binder.

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Founded upon facts in the life of the Empress dowager of China.

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"This volume forms the second series of Froude's Short studies, as reprinted in Everyman's library. The first volume, originally issued in the series with the title Essays in literature and history, contains a general introduction by M. Belloc to Froude's work and critical attitude in the Short studies."--v. 2, p. vii.

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A criticism of Max Nordau's "Degeneration," originally pub. in "Liberty", ed. by R. B. Tucker, with some other essays.

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Bibliography: p. 603-[610]

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En el presente trabajo exploramos las consecuencias de la lectura del argumento del lenguaje privado realizada por Kripke en el terreno del pensamiento social y político. Ello reviste un interés particular, debido a que lleva a revisar el encuadre en el que usualmente se ha situado la discusión sobre la relevancia político-social del pensamiento de Wittgenstein. La discusión ha estado centrada en el rol del acuerdo comunitario, sus consecuencias conservadoras o relativistas, el ahogo de la crítica y el disenso que resultaría, y otras cuestiones conexas. En ello vemos el síntoma de una problemática epistemológica (la de las garantías del conocimiento) que no termina de superarse, a pesar de la jerga semántica. Mostraremos que el escenario que resulta de la lectura de Kripke, en cambio, rompe con esta problemática, habilitando nuevas preocupaciones, próximas, a nuestro juicio, con las de lo que en el pensamiento francés se han denominado las "filosofías de la sujeción del sujeto"

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Thesis (Master's)--University of Washington, 2016-06

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For most of the past century, the prospect of replacing lost or damaged cells in the central nervous system (CNS) was hampered by the opinion that the adult mammalian CNS was incapable of generating new nerve cells. This belief, Like most dogmas, was essentially founded on a lack of experimental evidence to the contrary. The overturning of this 'no new neuron' hypothesis began midway through the twentieth century with a series of reports documenting neurogenesis in the postnatal and adult brain(1), continued with the isolation and in vitro culture of neurogenic cells from the adult mammalian brain(2,3), and culminated in the discovery of a population of muttipotent, selfrenewing cells in the adult CNS (that is, bona fide neural stem cells)(3-5). Although a variety of techniques were initially used, the neurosphere assay (NSA)(3,6) rapidly emerged as the assay of choice and has since become a valuable toot for isolating, and understanding the biology of, embryonic and adult CNS stem cells. Like all technologies, it is not without its limitations. In this article we will hightight several shortcomings of the assay related to its application and interpretation that we believe have led to a significant body of research whose conclusions may well be misleading.

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The phosphosulfomannan 1 (PI-88) is a mixture of highly sulfated oligosaccharides that is currently undergoing clinical evaluation in cancer patients. As well as it's anticancer properties, 1 displays a number of other interesting biological activities. A series of analogues of 1 were synthesized with a single carbon (pentasaccharide) backbone to facilitate structural characterization and interpretation of biological results. In a fashion similar to 1, all compounds were able to inhibit heparanase and to bind tightly to the proangiogenic growth factors FGF-1, FGF-2, and VEGF. The compounds also inhibited the infection of cells and cell-to-cell spread of herpes simplex virus (HSV-1). Preliminary pharmacokinetic data indicated that the compounds displayed different pharmacokinetic behavior compared with 1. Of particular note was the n-octyl derivative, which was cleared 3 times less rapidly than 1 and may provide increased systemic exposure.