937 resultados para 1127


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Drill cores are essential for the study of deep-sea sediments and on-land sites because often no suitable outcrop is available or accessible. These cores form the backbone of stratigraphical studies using and combining various dating techniques. Cyclostratigraphy is usually based on fast and inexpensive measurements of physical sediment properties. One indirect but highly valuable proxy for reconstructing the sediment composition and variability is sediment color. However, cracks and other disturbances in sediment cores may dramatically influence the quality of color data retrieved either directly from photospectrometry or derived from core image analysis. Here we present simple but powerful algorithms to extract color data from core images, and focus on routines to exclude cracks from these images. Results are discussed using the example of an ODP core from the Ceara Rise in the Central Atlantic. The crack correction approach presented highly improves the quality of color data and allows the easy incorporation of cracked cores into studies based on core images. This facilitates the quick and inexpensive generation of large color datasets directly from quantified core images, for cyclostratigraphy and other purposes.

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Quaternary sediments were recovered at all five sites drilled during Ocean Drilling Program (ODP) Leg 189 in the Tasmanian Gateway. Two of these sites lie north of the present-day Subtropical Front (STF), and three sites lie south of the STF. Quaternary sediments recovered at Sites 1168, 1170, 1171, and 1172 were studied in detail to determine the calcareous nannofossil biostratigraphy and construct an age model for these sediments. The Pliocene/Pleistocene boundary was identified by the last occurrence (LO) of Discoaster brouweri at Site 1172 and approximated by the LO of Calcidiscus macintyrei at the other sites because of a lack of discoasterids. A hiatus encompassing the entire Helicosphaera sellii Zone was tentatively identified at Sites 1168 and 1172 by the coincident LOs of C. macintyrei and H. sellii. Similar hiatuses have been noted at ODP Site 1127 on the Great Australian Bight, Deep Sea Drilling Project Site 282 off the Tasman subcontinent, and ODP Site 1165 in Prydz Bay, Antarctica.

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Acompaña plano:"Plano general de los edificios,obras,huerta,capilla y demás pertenencias del establecimiento de baños termales de las Caldas de Besaya...",firmado en Santander el 18 de junio de 1868.En tela,á dos tintas.Escala 1:500.31 x 1,64 cm.

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Mode of access: Internet.

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Also issued with t.p. reading: Yang cheng zhai shi quan ji [n.p.] Xiang xue cao lu cang ban, Jiaqing 5 [1800]

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Fine copy of al-Jaghmīnī's (d.1344) Qānūnchah, a compendium on medicine and an extract from Ibn Sīnā’s Qānūn. Brockelmann treats this author as distinct from an astronomer of the same name who died in 1221.

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Title from colophon

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Vol. 8 consists of "Appendix: parts 1 and 2. Report of the commissioner of corporations on the steel industry. Pt. I-II"; "General index to Hearings"; and "Investigation of United States steel corporation" (House rept. 1127, 62d Cong., 2d sess., submitted by Mr. Stanley, "Views of the minority" by Mr. Gardner and Mr. Young)

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A partir do estudo de caso de uma unidade pública de ensino, esta pesquisa almejou investigar a existência de mecanismos ideológicos presentes no discurso docente a cerca do fracasso escolar das camadas menos favorecidas, buscando captar algumas das estratégias acionadas pelos professores para se eximir de qualquer responsabilidade que possa recair sobre eles quanto ao baixo rendimento escolar dos alunos. Apoiado na conexão existente entre a valorização do capital cultural e os processo de seleção desempenhado pelo sistema escolar dentro do modelo capitalista e tendo como principais referenciais teóricos os autores Pierre Bourdieu & Jean Claude Passeron e Christian Baudelot & Roger Establet, os quais fazem uma crítica social ao sistema de ensino, pretendeu-se verificar a participação do professor enquanto agente social do sistema escolar, que contribui para a reprodução das relações sociais, buscando analisar como os docentes se reconhecem no sucesso ou fracasso escolar de seus aluno e os mecanismos ideológicos veiculados por eles para ocultar sua contribuição no processo de produção do fracasso escolar, em especial, dos alunos das classes sociais menos favorecidas, que muitas vezes são rotulados e estigmatizados como fracassados ou incapazes, por não conseguirem obter êxito nas atividades escolares.(AU)

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Objective: The aim of the study is to determine the effect of lutein combined with vitamin and mineral supplementation on contrast sensitivity in people with age-related macular disease (ARMD). Design: A prospective, 9-month, double-masked randomized controlled trial. Setting: Aston University, Birmingham, UK and a UK optometric clinical practice. Subjects: Age-related maculopathy (ARM) and atrophic age-related macular degeneration (AMD) participants were randomized (using a random number generator) to either placebo (n = 10) or active (n=15) groups. Three of the placebo group and two of the active group dropped out. Interventions: The active group supplemented daily with 6 mg lutein combined with vitamins and minerals. The outcome measure was contrast sensitivity (CS) measured using the Pelli-Robson chart, for which the study had 80% power at the 5% significance level to detect a change of 0.3log units. Results: The CS score increased by 0.07 ± 0.07 and decreased by 0.02 ± 0.18 log units for the placebo and active groups, respectively. The difference between these values is not statistically significant (z = 0.903, P = 0.376). Conclusion: The results suggest that 6 mg of lutein supplementation in combination with other antioxidants is not beneficial for this group. Further work is required to establish optimum dosage levels.

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This paper develops a theory of tourist satisfaction which is tested by using a consumerist gap scale derived from the Ragheb and Beard Leisure Motivation Scale. The sample consists of 1127 holiday makers from the East Midlands, UK. The results confirm the four dimensions of the original scale, and are used to develop clusters of holidaymakers. These clusters are found to be determinants of attitudes towards holiday destination attributes, and are independent of socio-demographic variables. Other determinants of holiday maker satisfaction are also examined. Among the conclusions drawn are the continuing importance of life cycle stages and previous holiday maker satisfaction. There is little evidence found for the travel career hypothesis developed by Professor Philip Pearce.

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We analyze the steady-state propagation of optical pulses in fiber transmission systems with lumped nonlinear optical devices (NODs) placed periodically in the line. For the first time to our knowledge, a theoretical model is developed to describe the transmission regime with a quasilinear pulse evolution along the transmission line and the point action of NODs. We formulate the mapping problem for pulse propagation in a unit cell of the line and show that in the particular application to nonlinear optical loop mirrors, the steady-state pulse characteristics predicted by the theory accurately reproduce the results of direct numerical simulations.

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Background - Our previous studies showed that the direct injection of an adenovirus construct expressing urokinase-type plasminogen activator (uPA) into experimental venous thrombi significantly reduces thrombus weight. The systemic use of adenovirus vectors is limited by inherent hepatic tropism and inflammatory response. As macrophages are recruited into venous thrombi, it is reasonable to speculate that these cells could be used to target the adenovirus uPA (ad-uPA) gene construct to the thrombus. The aims of this study were to determine whether macrophages transduced with ad-uPA have increased fibrinolytic activity and whether systemic injection of transduced cells could be used to target uPA expression to the thrombus and reduce its size. Methods - The effect of up-regulating uPA was examined in an immortalized macrophage cell line (MM6) and macrophages differentiated from human blood monocyte-derived macrophages (HBMMs). Cells were infected with ad-uPA or blank control virus (ad-blank). Fibrinolytic mediator expression, cell viability, and cytokine expression were measured by activity assays and enzyme-linked immunosorbent assays. Monocyte migration was measured using a modified Boyden chamber assay. A model of venous thrombosis was developed and characterized in mice with severe combined immunodeficiency (SCID). This model was used to study whether systemically administered macrophages over-expressing uPA reduced thrombus size. Uptake of HBMMs into the thrombus induced in these mice was confirmed by a combination of PKH2-labeled cell tracking and colocalization with human leukocyte antigen (HLA) by immunohistology. Results - Compared with ad-blank, treated HBMMs transduction with ad-uPA increased uPA production by >1000-fold (P = .003), uPA activity by 150-fold (P = .0001), and soluble uPA receptor (uPAR) by almost twofold (P = .043). Expression of plasminogen activator inhibitor (PAI-1) and PAI-2 was decreased by about twofold (P = .011) and threefold (P = .005), respectively. Up-regulation of uPA had no effect on cell viability or inflammatory cytokine production compared with ad-blank or untreated cells. Ad-uPA transduction increased the migration rate of HBMMs (about 20%, P = .03) and MM6 cells (>twofold, P = .005) compared with ad-blank treated controls. Human macrophage recruitment into the mouse thrombus was confirmed by the colocalization of HLA with the PKH2-marked cells. Systemic injection of uPA-up-regulated HBMMs reduced thrombus weight by approximately 20% compared with ad-blank (P = .038) or sham-treated controls (P = .0028). Conclusion - Transduction of HBBM with ad-uPA increases their fibrinolytic activity. Systemic administration of uPA up-regulated HBBMs reduced thrombus size in an experimental model of venous thrombosis. Alternative methods of delivering fibrinolytic agents are worth exploring.