Of property, and of its equal distribution, as promoting virtue, population, abundance,

"Works by the late George Ensor," p. [6] at beginning.

Compiled and revised ordinances of the City of East Orange: published by the City of East Orange under authority of the Legislature by virtue of chapter 123 of the laws of 1915, approved March 30, 1915.

Includes index.

The English reader : or, Pieces in prose and poetry, selected from the best writers : designed to assist young persons to read with propriety and effect, to improve their language and sentiments; and to inculcate some of the more important principles of piety and virtue : with a few preliminary observations on the principles of good reading /

Mode of access: Internet.

Sequel to the English reader : or, Elegant selections in prose and poetry : designed to improve the highest class of learners in reading, to establish a taste for just and accurate composition, and to promote the interests of piety and virtue /

Mode of access: Internet.

The visitation of the county of Warwick, begun by Thomas May, Chester, and Gregory King, Rouge dragon, in Hilary vacacōn, 1682. Reviewed by them in the Trinity vacacōn following, and finished by Henry Dethick Richmond, and said rouge dragon pursuiv in Trinity vacation, 1683, by virtue of several deputations from Sir Henry St. George, Clarenceux king of arms.

Report of the society for the year 1910 (3 p.) appended.

The blindness of virtue,

Drama.

Blowing the virtue-ethics whistle: Response to Faunce

The author elaborates some issues raised in the theoretical basis of whistleblowing put forward by Faunce. The author considers the relationship between bioethics teaching and professional behaviour and the role of principlism in teaching bioethics and medical ethics.

The importance of character : virtue ethics and psychology

Mémoire numérisé par la Direction des bibliothèques de l'Université de Montréal.

From project ontologies to communities of virtue

Projects, as an organizing principle, can provide exciting contexts for innovative work. Thus far, project management discourse has tended to privilege the vital need to deliver projects ‘on time, on budget, and to specification’. In common with the call for papers for this workshop we suggest that perhaps the “instrumental rationality” underpinning this language of characterising project activity may create more problems than it solves. In this paper we suggest that such questions (and language) frame project contexts in a partial way. We argue that such concerns stem from a particular worldview or ontology, which we identify as a ‘being’ ontology. Here we contrast being and becoming project ontologies, to explore the questions, methods and interventions that each foregrounds. In an attempt to move this dialogue further than simply another contrast of modern and postmodernist accounts of project organising, we go on to consider some possible ethical concomitants of valuing being and becoming ontologies in project contexts.

The importance of character : virtue ethics and psychology

Mémoire numérisé par la Direction des bibliothèques de l'Université de Montréal.

Mandevillian Intelligence: From Individual Vice to Collective Virtue

Abstract Mandevillian intelligence is a specific form of collective intelligence in which individual cognitive vices (i.e., shortcomings, limitations, constraints and biases) are seen to play a positive functional role in yielding collective forms of cognitive success. In this talk, I will introduce the concept of mandevillian intelligence and review a number of strands of empirical research that help to shed light on the phenomenon. I will also attempt to highlight the value of the concept of mandevillian intelligence from a philosophical, scientific and engineering perspective. Inasmuch as we accept the notion of mandevillian intelligence, then it seems that the cognitive and epistemic value of a specific social or technological intervention will vary according to whether our attention is focused at the individual or collective level of analysis. This has a number of important implications for how we think about the cognitive impacts of a number of Web-based technologies (e.g., personalized search mechanisms). It also forces us to take seriously the idea that the exploitation (or even the accentuation!) of individual cognitive shortcomings could, in some situations, provide a productive route to collective forms of cognitive and epistemic success. Speaker Biography Dr Paul Smart Paul Smart is a senior research fellow in the Web and Internet Science research group at the University of Southampton in the UK. He is a Fellow of the British Computer Society, a professional member of the Association of Computing Machinery, and a member of the Cognitive Science Society. Paul’s research interests span a number of disciplines, including philosophy, cognitive science, social science, and computer science. His primary area of research interest relates to the social and cognitive implications of Web and Internet technologies. Paul received his bachelors degree in Psychology from the University of Nottingham. He also holds a PhD in Experimental Psychology from the University of Sussex.

O papel da propriocepção no desenvolvimento da força muscular e da flexibilidade

Universidade Estadual de Campinas . Faculdade de Educação Física

A Vaccine Encoding Conserved Promiscuous HIV CD4 Epitopes Induces Broad T Cell Responses in Mice Transgenic to Multiple Common HLA Class II Molecules

Current HIV vaccine approaches are focused on immunogens encoding whole HIV antigenic proteins that mainly elicit cytotoxic CD8+ responses. Mounting evidence points toward a critical role for CD4+ T cells in the control of immunodeficiency virus replication, probably due to cognate help. Vaccine-induced CD4+ T cell responses might, therefore, have a protective effect in HIV replication. In addition, successful vaccines may have to elicit responses to multiple epitopes in a high proportion of vaccinees, to match the highly variable circulating strains of HIV. Using rational vaccine design, we developed a DNA vaccine encoding 18 algorithm-selected conserved, ""promiscuous"" ( multiple HLA-DR-binding) B-subtype HIV CD4 epitopes - previously found to be frequently recognized by HIV-infected patients. We assessed the ability of the vaccine to induce broad T cell responses in the context of multiple HLA class II molecules using different strains of HLA class II-transgenic mice (-DR2, -DR4, -DQ6 and -DQ8). Mice displayed CD4+ and CD8+ T cell responses of significant breadth and magnitude, and 16 out of the 18 encoded epitopes were recognized. By virtue of inducing broad responses against conserved CD4+ T cell epitopes that can be recognized in the context of widely diverse, common HLA class II alleles, this vaccine concept may cope both with HIV genetic variability and increased population coverage. The vaccine may thus be a source of cognate help for HIV-specific CD8+ T cells elicited by conventional immunogens, in a wide proportion of vaccinees.

A DNA Vaccine Encoding Multiple HIV CD4 Epitopes Elicits Vigorous Polyfunctional, Long-Lived CD4(+) and CD8(+) T Cell Responses

T-cell based vaccines against HIV have the goal of limiting both transmission and disease progression by inducing broad and functionally relevant T cell responses. Moreover, polyfunctional and long-lived specific memory T cells have been associated to vaccine-induced protection. CD4(+) T cells are important for the generation and maintenance of functional CD8(+) cytotoxic T cells. We have recently developed a DNA vaccine encoding 18 conserved multiple HLA-DR-binding HIV-1 CD4 epitopes (HIVBr18), capable of eliciting broad CD4(+) T cell responses in multiple HLA class II transgenic mice. Here, we evaluated the breadth and functional profile of HIVBr18-induced immune responses in BALB/c mice. Immunized mice displayed high-magnitude, broad CD4(+)/CD8(+) T cell responses, and 8/18 vaccine-encoded peptides were recognized. In addition, HIVBr18 immunization was able to induce polyfunctional CD4(+) and CD8(+) T cells that proliferate and produce any two cytokines (IFN gamma/TNF alpha, IFN gamma/IL-2 or TNF alpha/IL-2) simultaneously in response to HIV-1 peptides. For CD4(+) T cells exclusively, we also detected cells that proliferate and produce all three tested cytokines simultaneously (IFN gamma/TNF alpha/IL-2). The vaccine also generated long-lived central and effector memory CD4(+) T cells, a desirable feature for T-cell based vaccines. By virtue of inducing broad, polyfunctional and long-lived T cell responses against conserved CD4(+) T cell epitopes, combined administration of this vaccine concept may provide sustained help for CD8(+) T cells and antibody responses-elicited by other HIV immunogens.