1000 resultados para Vasco Graça Moura (1942-2014)
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This paper has approached the coastal and Atlantic characters of such commercial activity in the port of Santos between 1808 and 1822 and the contradictions arising of this double condition, which is unique in the Southern coast of Portuguese America. This discussion was based on data collected in importation and exportation maps produced by customs of Santos to the Royal Board of Trade.
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O objetivo desta comunicação foi descrever a detecção de coexistência de variantes HIV-1 com inserções de dois aminoácidos entre os códons 69 e 70 da transcriptase reversa. Tais variantes foram isoladas de paciente do sexo masculino, 16 anos de idade, em tratamento no interior do estado de São Paulo. Após confirmação de falha terapêutica, foi realizado teste de resistência a antirretrovirais, a partir do qual foram detectadas duas variantes contendo inserções dos aminoácidos Ser-Gly/Ser-Ala no códon 69 da transcriptase reversa, além da mutação T69S. Tais inserções possuem baixa prevalência, não foram relatadas em caráter de coexistência no Brasil e estão relacionadas com a resistência a múltiplas drogas, tornando o achado relevante do ponto de vista epidemiológico.
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Pós-graduação em Engenharia Elétrica - FEIS
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Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
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Septins (SEPTs) form a family of GTP-binding proteins implicated in cytoskeleton and membrane organization, cell division and host/pathogen interactions. The precise function of many family members remains elusive. We show that SEPT6 and SEPT7 complexes bound to F-actin regulate protein sorting during multivesicular body (MVB) biogenesis. These complexes bind AP-3, an adapter complex sorting cargos destined to remain in outer membranes of maturing endosomes, modulate AP-3 membrane interactions and the motility of AP-3-positive endosomes. These SEPT-AP interactions also influence the membrane interaction of ESCRT (endosomal-sorting complex required for transport)-I, which selects ubiquitinated cargos for degradation inside MVBs. Whereas our findings demonstrate that SEPT6 and SEPT7 function in the spatial, temporal organization of AP-3- and ESCRT-coated membrane domains, they uncover an unsuspected coordination of these sorting machineries during MVB biogenesis. This requires the E3 ubiquitin ligase LRSAM1, an AP-3 interactor regulating ESCRT-I sorting activity and whose mutations are linked with Charcot-Marie-Tooth neuropathies.
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The present work has as objective the development of ceramic pigments based in iron oxides and cobalt through the polymeric precursor method, as well as study their characteristics and properties using methods of physical, chemical, morphological and optical characterizations.In this work was used iron nitrate, and cobalt citrate as precursor and nanometer silica as a matrix. The synthesis was based on dissolving the citric acid as complexing agent, addition of metal oxides, such as chromophores ions and polymerization with ethylene glycol. The powder obtained has undergone pre-ignition, breakdown and thermal treatments at different calcination temperatures (700 °C, 800 °C, 900 °C, 1000 °C and 1100 °C). Thermogravimetric analyzes were performed (BT) and Differential Thermal Analysis (DTA), in order to evaluate the term decomposition of samples, beyond characterization by techniques such as BET, which classified as microporous materials samples calcined at 700 ° C, 800 º C and 900 º C and non-porous when annealed at 1000 ° C and 1100 º C, X-ray diffraction (XRD), which identified the formation of two crystalline phases, the Cobalt Ferrite (CoFe2O4) and Cristobalite (SiO2), Scanning Electron Microscopy (SEM) revealed the formation of agglomerates of particles slightly rounded;and Analysis of Colorimetry, temperature of 700 °C, 800 °C and 900 °C showed a brown color and 1000 °C and 1100 °C violet
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Recoger datos que puedan ser utlizados un día en la realización de la historia del fenómeno de la Ikastola. Historia de la Educación. En la primera parte de este estudio se realiza un esbozo de la historia de la Ikastola en San Sebastián entre los años 1942 y 1969. La segunda parte se refiere a la labor desempeñada por la Andereño Elvira Cipitria entre los años 1942 y 1969 en San Sebastián, realizada mediante entrevistas -efectuadas en Euskera- y documentos acreditativos de aquello que se reseña. Entrevistas de carácter oral constituidas por las vivencias y los recuerdos de personas que conocieron de cerca a Elvira Cipitria. Documentos Oficiales. Análisis teórico.
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Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
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521 p.
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Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
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Dissertação para obtenção do grau de Mestre em Engenharia Civil na Área de especialização de Vias de Comunicação e Transportes