Debates, resolutions and other proceedings of the convention of the commonwealth of Massachusetts : Convened at Boston, on the 9th of January, 1788, and continued until the 7th of February following, for the purpose of assenting to and ratifying the Constitution recommended by the grand federal convention. : Together with the yeas and nays on the decision of the grand question. : To which the federal Constitution is prefixed; and to which are added, the amendments which have been made therein.

Shaw & Shoemaker

Some of the points of difference between Unitarian and orthodox Christians /

Mode of access: Internet.

Efficacy and Safety of Natalizumab in Crohn’s Disease Patients Treated at 6 Boston Academic Hospitals

BACKGROUND: Despite trials demonstrating its efficacy, many physicians harbor concerns regarding the use of natalizumab in the treatment of patients with refractory Crohn's disease (CD). The purpose of this study was to perform a descriptive analysis of a series of CD patients not currently enrolled in a clinical trial. METHODS: A retrospective case review of patients treated with natalizumab at 6 sites in Massachusetts: Boston Medical Center, Beth Israel Deaconess Medical Center, Brigham & Women's Hospital, Lahey Clinic, Massachusetts General Hospital, and UMass Medical Center. RESULTS: Data on 69 CD patients on natalizumab were collected. At the start of treatment, patients' disease duration was 12 years. A high proportion of patients were women (68%), presented with perianal disease (65%) and upper gastrointestinal tract involvement (14%). Prior nonbiologic therapies were steroids (96%), thiopurines (94%), antibiotics (74%), methotrexate (58%), and at least two anti-tumor necrosis factor agent failures (81%). Sixty-nine percent (44 of 64 patients) with available medical evaluation had a partial or complete clinical response. Loss of response was 13% after an average of 1 year of treatment. Adverse events were infusion reactions, headaches, fever, and infections. No case of progressive multifocal leukoencephalopathy was observed. CONCLUSIONS: In our clinical experience outside the context of a clinical trial, natalizumab is largely reserved for CD patients with extensive ileocolonic disease who have failed conventional immunosuppressants and of at least 2 anti-tumor necrosis factor agents. This drug is, however, well tolerated and offers significant clinical improvement for more than a year in one-third of these difficult-to-treat CD patients.

A collection of the most approved pieces of music from various authors: transcribed while member of Harvard University, from July 1789 to July 1793

John Pierce kept this journal while he was a student at Harvard College. It consists of manuscript musical scores with annotations indicating the occasions at which the music was performed. These occasions included commencements, public exhibitions and Dudleian lectures. A note indicates that one anthem was prepared by Samuel Holyoke at Pierce's request, to be performed at Pierce's class commencement exercises, held on July 13, 1793. Several annotations were made in May 1794, the year following Pierce's graduation. There is a table of contents on the last page.

Notes on cases in Boston, 1784-1790

Notes on various cases, including cases of burglary, debt, fraud, libel, receiving stolen goods, and one case of attempted murder of an infant by his mother.

Indenture acknowledging sale of property, Boston, 1753

Document acknowledges the sale of the late Samuel Clark's house and property to Alexander Hill. Samuel Clark's executor, James Clark, was required by law to sell the property to the highest bidder in order to pay the debts of the deceased.

At a court of admiralty held at Boston ... the 22d day of 1704 was condemned the briggantine Charles whereof John Quelch was late commander ... , 1704

Attestation regarding the trial of Quelch and other defendants, who were convicted of piracy. Signed: John Valentine, registrar.

Deeds for properties in Boston [and Cambridge?], 1798-approximately 1945 (inclusive); approximately 1880-1920 (bulk)

This group of records contains deeds and related documents for a selection of properties owned by Harvard University in Boston and possibly Cambridge and other nearby communities through the mid 1940s. Documents include deeds, assignments of mortgages, receipts, correspondence, and other legal documents. Many of the documents record property transfers prior to Harvard's acquisition of the property, and often the documents do not fully identify Harvard's involvement with the property. The bulk of the documents date from the late 19th and early 20th centuries.

Boston 2000: harbor nodes, modes & links

Shows transportation network in and around the harbor.

Boston Harbor bathymetry

Shows soundings in Boston Harbor between Winthrop and Hingham.

Massachusetts Bay and Coastline, Nautical Chart, 1776 (Image 1 of 2) (Raster Image)

This layer is a georeferenced raster image of the untitled, historic nautical chart: [A chart of Massachusetts Bay & coast from Cape Ann to Cape Cod] (sheet originally published in 1776). The map is [sheet 15] from the Atlantic Neptune atlas Vol. 3 : Charts of the coast and harbors of New England, from surveys taken by Samuel Holland and published by J.F.W. Des Barres, 1781. Scale [ca. 1:125,000]. This layer is image 1 of 2 total images of the two sheet source map, representing the western portion of the map. Covers coast of Massachusetts, Boston Harbor, and portion of Massachusetts Bay. The image is georeferenced to the surface of the earth and fit to the 'World Mercator' (WGS 84) projected coordinate system. All map collar information is also available as part of the raster image, including any inset maps, profiles, statistical tables, directories, text, illustrations, or other information associated with the principal map. This map shows coastal features such as harbors, inlets, rocks, channels, points, coves, shoals, islands, and more. Includes also selected land features such as cities and towns. This layer is part of a selection of digitally scanned and georeferenced historic maps from The Harvard Map Collection. The entire Atlantic Neptune atlas Vol. 3 : Charts of the coast and harbors of New England has been scanned and georeferenced as part of this selection.

A record of the ceremony and oration on the occasion of the unveiling of the monument commemorating the Great Swamp fight : December 19, 1675, in the Narragansett country, Rhode Island : erected by the Societies of Colonial wars of Rhode Island and Massachusetts, October 20, 1906.

Compiled by Rowland G. Hazard.

Theological views : comprising the substance of teachings during a ministry of thirty-five years, in New Orleans /

The existence and attributes of God -- The Bible -- Christian miracles -- Objections to the miracles of the New Testament answered -- Thoughts on the subject of sin -- The teachings of Scripture concerning punishment -- An examination of some of the erroneous interpretations of Scripture with respect to future retribution -- Exposition of Matthew 25:41 -- Parable of Dives and Lazarus -- The teachings of Jesus and his Apostles concerning the Resurrection and a future state -- On grace.

Celebration of the introduction of the water of Cochituate Lake into the city of Boston : October 25, 1848.

"Ode" ("My name is water! I have sped ...) by James Russell Lowell: p. 21-22.

The claims of Puritanism : a sermon preached at the annual election, May 31, 1826 : before His Excellency, Levi Lincoln, governor, the honorable Council, and the legislature of Massachusetts /

Mode of access: Internet.