Adolpf Molling, Janet Krakauer nee McColl, Hymie Joachim and Thomas Krakauer (l-r); Weggis, Switzerland Portraits Groups

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Audience members watching the opening ceremonies of the Heidelberg festival, with opening speech given by Thomas Mann.

Typed caption: Festakt in der Stadthalle zur Eroeffnung der Heidelberger Festpiele 1929. Thomas Mann hielt die Festrede. Unsere Aufnahme zeigt einen Ausschnitt aus der Festversammlung, an der die geistige Prominenz Heidelbergs und zahlreiche bedeutende Persoenlichkeiten des deutschen Kulturlebends teilnahmen. Von links nach rechts in der 1. Reihe: Rene Schickele, Rudolf Rittner, Gustav Hargung, Prof. Dr. Martin Dibelius, Gerhart Hauptmann, Dr. Rudolf H. Goldschmidt, Oberbuergermeister Dr. Neinhaus, Thomas Mann und Frau, Kultusminister Leers, Rudolf G. Binding; In der 3. Reihe: Oberbaurat L. Schmieder, Nobelpreistraeger Dr. F. Bergius, Bankdirektor Fremerey, Prof. Hellpach, Prof. Radbruch

Plan zemelʻnogo otvoda s.kh. arteli "Krasnyĭ Pakharʻ" Krivorogskogo okruga Sofievskogo raĭona ploshchadi︠u︡ 1380 desi︠a︡tin

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Plan zemelʻnogo otvoda s.-kh. arteli "Krasnyĭ Pakharʻ" Krivorogskogo okruga, Sofievskogo raĭona ploshchadiʻ︠u︡ 1380 desi︠a︡tin

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Letter from Thomas Hope, architect, regarding drawings for ark of new synagogue

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Implications of high level pseudogene transcription in Mycobacterium leprae

Background: The Mycobacterium leprae genome has less than 50% coding capacity and 1,133 pseudogenes. Preliminary evidence suggests that some pseudogenes are expressed. Therefore, defining pseudogene transcriptional and translational potentials of this genome should increase our understanding of their impact on M. leprae physiology. Results: Gene expression analysis identified transcripts from 49% of all M. leprae genes including 57% of all ORFs and 43% of all pseudogenes in the genome. Transcribed pseudogenes were randomly distributed throughout the chromosome. Factors resulting in pseudogene transcription included: 1) co-orientation of transcribed pseudogenes with transcribed ORFs within or exclusive of operon-like structures; 2) the paucity of intrinsic stem-loop transcriptional terminators between transcribed ORFs and downstream pseudogenes; and 3) predicted pseudogene promoters. Mechanisms for translational ``silencing'' of pseudogene transcripts included the lack of both translational start codons and strong Shine-Dalgarno (SD) sequences. Transcribed pseudogenes also contained multiple ``in-frame'' stop codons and high Ka/Ks ratios, compared to that of homologs in M. tuberculosis and ORFs in M. leprae. A pseudogene transcript containing an active promoter, strong SD site, a start codon, but containing two in frame stop codons yielded a protein product when expressed in E. coli. Conclusion: Approximately half of M. leprae's transcriptome consists of inactive gene products consuming energy and resources without potential benefit to M. leprae. Presently it is unclear what additional detrimental affect(s) this large number of inactive mRNAs has on the functional capability of this organism. Translation of these pseudogenes may play an important role in overall energy consumption and resultant pathophysiological characteristics of M. leprae. However, this study also demonstrated that multiple translational ``silencing'' mechanisms are present, reducing additional energy and resource expenditure required for protein production from the vast majority of these transcripts.

Thomas-Fermi Method For Particles Obeying Generalized Exclusion Statistics

We use the Thomas-Fermi method to examine the thermodynamics of particles obeying Haldane exclusion statistics. Specifically, we study Calogero-Sutherland particles placed in a given external potential in one dimension. For the case of a simple harmonic potential (constant density of states), we obtain the exact one-particle spatial density and a {\it closed} form for the equation of state at finite temperature, which are both new results. We then solve the problem of particles in a $x^{2/3} ~$ potential (linear density of states) and show that Bose-Einstein condensation does not occur for any statistics other than bosons.

Variational Approach to the Thomas-Fermi Equation

By the semi-inverse method, a variational principle is obtained for the Thomas-Fermi equation, then the Ritz method is applied to solve an analytical solution, which is a much simpler and more efficient method.

Las escenas espejo en el teatro isabelino : el jardín de Isabel en “La tragedia española” de Thomas Kyd

Resumen: Este trabajo busca demostrar cómo la escena de “El Jardín de Isabel” (acto IV, escena ii) en la obra La tragedia española de Thomas Kyd es un ejemplo de una escena espejo. Inicialmente se observa cómo esta escena está laxamente conectada con el resto de la obra y la misma no sufriría un cambio significativo de ser la escena eliminada; la característica de “prescindible” de ésta, es propia de una escena espejo. La escena del Jardín de Isabel es luego estudiada en profundidad para dejar en evidencia cómo resume la obra y la simboliza. El personaje de Isabel es examinado en detalle, siguiendo una sensibilidad pictórica y, a través de una interpretación temática y simbólica, Isabel es presentada como Piedad, Testigo de Justicia Divina y Venganza. Finalmente el espacio es también analizado como locus amoenus al ser inicialmente un lugar de encuentro de los enamorados y locus eremus luego de la maldición de Isabel. Luego del estudio de estos aspectos de esta escena espejo, se pone en evidencia cómo la misma “refleja” los temas centrales de la obra: la verdad se revela con el tiempo, hay que ser paciente y esperar la justicia divina y, por último, la venganza sólo condena al vengador.

Restauracion de la ciudad del Salvador, i Baia de Todos-Santos, en la provincia del Brasil :por las armas de Don Philippe IV, el Grande, Rei Catholico de las Espanas i Indias, [et]c. A su Magestad : Don Thomas Tamaio de Vargas, su cronista

Tomás Tamayo de Vargas, historiador espanhol, nasceu em 1588 e morreu em 1641. Cronista do Reino, escreveu essa obra por ordem real, que foi publicada em 1628, utilizando documentação oficial e informações que as relações da época lhe proporcionavam. ‘Restauracion de la ciudad del Salvador, i Baia de Todos-Sanctos, en la Provincia del Brasil’ reflete a opinião oficial espanhola sobre a restauração da Bahia e mostra a repercussão que o acontecimento teve na metrópole espanhola que, na época, dominava o Brasil. Rodrigues considera essa uma edição ‘rara’ e Brunet afirma ser ‘muito rara’. Há uma edição brasileira, difícil de encontrar, publicada em Salvador pela Tipografia de Epifanio Pedroza (1847)

Celiac disease in the Mediterranean area

Background: The World Gastroenterology Organization recommends developing national guidelines for the diagnosis of Celiac Disease (CD): hence a profile of the diagnosis of CD in each country is required. We aim to describe a cross-sectional picture of the clinical features and diagnostic facilities in 16 countries of the Mediterranean basin. Since a new ESPGHAN diagnostic protocol was recently published, our secondary aim is to estimate how many cases in the same area could be identified without a small intestinal biopsy. Methods: By a stratified cross-sectional retrospective study design, we examined clinical, histological and laboratory data from 749 consecutive unselected CD children diagnosed by national referral centers. Results: The vast majority of cases were diagnosed before the age of 10 (median: 5 years), affected by diarrhea, weight loss and food refusal, as expected. Only 59 cases (7.8%) did not suffer of major complaints. Tissue transglutaminase (tTG) assay was available, but one-third of centers reported financial constraints in the regular purchase of the assay kits. 252 cases (33.6%) showed tTG values over 10 times the local normal limit. Endomysial antibodies and HLA typing were routinely available in only half of the centers. CD was mainly diagnosed from small intestinal biopsy, available in all centers. Based on these data, only 154/749 cases (20.5%) would have qualified for a diagnosis of CD without a small intestinal biopsy, according to the new ESPGHAN protocol. Conclusions: This cross-sectional study of CD in the Mediterranean referral centers offers a puzzling picture of the capacities to deal with the emerging epidemic of CD in the area, giving a substantive support to the World Gastroenterology Organization guidelines.

Da impossibilidade da lucidez: a dissolução do Século XX em O arco-íris da gravidade, de Thomas Pynchon

Esta tese analisa a relação entre a ficcionalização da História Moderna e o desenvolvimento de uma ética da vida cotidiana no romance O arco-íris da gravidade, do norte-americano Thomas Pynchon. Para a sua análise e interpretação, será desenvolvido, no primeiro capítulo, um aporte teórico-metodológico que coteje a complexidade formal da narrativa (que dificulta a sua síntese temática) para se estabelecer, a partir daí, as condições de possibilidade de detecção de núcleos temáticos recorrentes que, numa rede de interconexões não-concêntrica ou dispersiva , perspectivizam no romance uma totalização fraturada do sistema-mundo moderno e contemporâneo. No segundo capítulo a ficcionalização do século XX é apresentada em suas configurações metafísica e intra-mundana, e no capítulo final são analisadas as condições que ela impõe para a formação, dentro do real ficcional, de rotinas e modos de vida eticamente positivos