Report of the Workshop on Development and Application of Sampling Frames and Sample Designs for Integrated Household Survey Programmes in the Caribbean

Includes bibliography

Procedimientos de la Consulta sobre el Desarrollo de las Industrias Forestales y de la Pulpa y Papel en América Latina = Proceedings of the Consultation on Development of the Forest and Pulp and Paper Industries in Latin America

Incluye Bibliografía

Note on United Nations Interregional Workshop on Development Planning for Small Island Countries

Informe de la reunion cuyo objetivo fue definir los problemas economicos de las Islas del Caribe y las acciones especificas a tomar para resolver sus necesidades particulares en la planificacion del desarrollo.

Comparative study of policies on technology and industry in the Caribbean and their effects on development

Includes bibliography

El maremoto de septiembre de 1992 en Nicaragua y sus efectos sobre el desarrollo = The tsunami of September 1992 in Nicaragua and its effects on development

Incluye Bibliografía

Diagnosis of constraints on development and on further economic integration

The purpose of the present document is to set forth the diagnosis of infrastructure services in Latin America and the Caribbean carried out by the Infrastructure Services Unit of ECLAC. Although much of the diagnosis presented is applicable to all economic infrastructure services, this document places a strong emphasis on transport infrastructure and services, as their characteristics make them a potential constraint on the region’s economic and social development and on its continuing integration.

Reflections on the need for a new discourse on development

This issue of the FAL bulletin reflects on the need to place a new discourse at the centre of the academic, social and political debate, in relation to developing infrastructure services in a sustainable way.

Neonatally induced mild diabetes: influence on development, behavior and reproductive function of female Wistar rats

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Effects of therapeutic approach on the neonatal evolution of very low birth weight infants with patent ductus arteriosus

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

A new approach on the stability analysis in ELKO cosmology

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

Neonatally induced mild diabetes: influence on development, behavior and reproductive function of female Wistar rats

Abstract Background Neonatal STZ treatment induces a state of mild hyperglycemia in adult rats that disrupts metabolism and maternal/fetal interactions. The aim of this study was investigate the effect of neonatal STZ treatment on the physical development, behavior, and reproductive function of female Wistar rats from infancy to adulthood. Methods At birth, litters were assigned either to a Control (subcutaneous (s.c.) citrate buffer, n = 10) or STZ group, (streptozotocin (STZ) - 100 mg/kg-sc, n = 6). Blood glucose levels were measured on postnatal days (PND) 35, 84 and 120. In Experiment 1 body weight, length and the appearance of developmental milestones such as eye and vaginal opening were monitored. To assess the relative contribution of the initial and long term effects of STZ treatment this group was subdivided based on blood glucose levels recorded on PND 120: STZ hyperglycemic (between 120 and 300 mg/dl) and STZ normoglycemic (under 120 mg/dl). Behavioral activity was assessed in an open field on PND 21 and 75. In Experiment 2 estrous cyclicity, sexual behavior and circulating gonadotropin, ovarian steroid, and insulin levels were compared between control and STZ-hyperglycemic rats. In all measures the litter was the experimental unit. Parametric data were analyzed using one-way or, where appropriate, two-way ANOVA and significant effects were investigated using Tukey’s post hoc test. Fisher’s exact test was employed when data did not satisfy the assumption of normality e.g. presence of urine and fecal boli on the open field between groups. Statistical significance was set at p < 0.05 for all data. Results As expected neonatal STZ treatment caused hyperglycemia and hypoinsulinemia in adulthood. STZ-treated pups also showed a temporary reduction in growth rate that probably reflected the early loss of circulating insulin. Hyperglycemic rats also exhibited a reduction in locomotor and exploratory behavior in the open field. Mild hyperglycemia did not impair gonadotropin levels or estrous cylicity but ovarian steroid concentrations were altered. Conclusions In female Wistar rats, neonatal STZ treatment impairs growth in infancy and results in mild hyperglycemia/hypoinsulinemia in adulthood that is associated with changes in the response to a novel environment and altered ovarian steroid hormone levels.